Detailed information NTG0369099

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FIV54_RS00740
• Genome accession: NZ_CP041037
• Coordinates: 161218..162105 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain NP66
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 156218..167105

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIV54_RS00710 (FIV54_00710)	-	156950..157711 (+)	762	WP_000323447.1	alpha/beta hydrolase family protein	-
FIV54_RS00715 (FIV54_00715)	-	157956..158411 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FIV54_RS13980 (FIV54_00720)	-	158533..158634 (+)	102	WP_000731976.1	SE2200 family small protein	-
FIV54_RS00725 (FIV54_00725)	-	158694..160118 (-)	1425	WP_000953747.1	alkaline phosphatase	-
FIV54_RS00730 (FIV54_00730)	-	160316..160516 (+)	201	WP_000604727.1	hypothetical protein	-
FIV54_RS00735 (FIV54_00735)	braR	160542..161207 (+)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FIV54_RS00740 (FIV54_00740)	braS	161218..162105 (+)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FIV54_RS00745 (FIV54_00745)	-	162213..162968 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FIV54_RS00750 (FIV54_00750)	-	162965..164965 (+)	2001	WP_000776751.1	ABC transporter permease	-
FIV54_RS00755 (FIV54_00755)	-	165624..165737 (+)	114	WP_011447078.1	hypothetical protein	-
FIV54_RS00765 (FIV54_00765)	-	166119..166379 (+)	261	WP_001789910.1	hypothetical protein	-
FIV54_RS00770 (FIV54_00770)	-	166389..166886 (+)	498	WP_001065268.1	glutathione peroxidase	-
FIV54_RS00775 (FIV54_00775)	-	166994..167086 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=369099 FIV54_RS00740 WP_000143419.1 161218..162105(+) (braS) [Staphylococcus aureus strain NP66]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=369099 FIV54_RS00740 WP_000143419.1 161218..162105(+) (braS) [Staphylococcus aureus strain NP66]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997