Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FY149_RS12080 Genome accession   NZ_CP048493
Coordinates   366591..368423 (-) Length   610 a.a.
NCBI ID   WP_099086150.1    Uniprot ID   -
Organism   Agrobacterium tumefaciens strain Tul001     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 361591..373423
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FY149_RS12055 (FY149_12000) - 362281..362520 (+) 240 WP_003503155.1 DUF4170 domain-containing protein -
  FY149_RS12060 (FY149_12005) waaA 362735..364057 (+) 1323 WP_003503153.1 lipid IV(A) 3-deoxy-D-manno-octulosonic acid transferase -
  FY149_RS12065 (FY149_12010) - 364051..364788 (+) 738 WP_003503151.1 HAD family hydrolase -
  FY149_RS12070 (FY149_12015) lpxK 364938..365984 (+) 1047 WP_099085618.1 tetraacyldisaccharide 4'-kinase -
  FY149_RS12075 (FY149_12020) - 366218..366439 (-) 222 WP_003503147.1 DUF2093 domain-containing protein -
  FY149_RS12080 (FY149_12025) hexB 366591..368423 (-) 1833 WP_099086150.1 DNA mismatch repair endonuclease MutL Machinery gene
  FY149_RS12085 (FY149_12030) - 368833..370452 (+) 1620 WP_060726390.1 response regulator -
  FY149_RS12090 (FY149_12035) - 370539..371891 (+) 1353 WP_003503140.1 putative bifunctional diguanylate cyclase/phosphodiesterase -
  FY149_RS12095 (FY149_12040) - 372076..372963 (-) 888 WP_099086149.1 SMP-30/gluconolactonase/LRE family protein -

Sequence

Protein


Download         Length: 610 a.a.        Molecular weight: 65574.44 Da        Isoelectric Point: 6.0819

>NTDB_id=368969 FY149_RS12080 WP_099086150.1 366591..368423(-) (hexB) [Agrobacterium tumefaciens strain Tul001]
MAIKQLSETLINQIAAGEVIERPSSATKELVENAIDAGATRIEIATAGGGKGLVRITDNGSGMSPADLELAVRRHCTSKI
SDTLDDIRTLGFRGEALPSIGSVAKLTITSRQQGAEQGSVISVTGGKVSDVRPAASNAGTIVEVRDLFFATPARLKFLKT
ERAEAAAITEVVKRMAIAFPHIRFVLSGTDRSTLEIPSTGDDHLARMAQILGAEFKDNAIEIDAGREDVTLTGFAGVPTF
NRGNSAHQYVFVNGRPVQDKLLLSAIRGAYAETVPHGRYPVAVLSITLDPAFVDVNVHPAKSDVRFRDPGLIRGLIVGAI
RQALTRDGDRAATTGASQMMNAFRPGYSPSGIRPSPSMAAAAPWSAATSPSRPLAVSGDMQFAEAVQSRFSDITMPTARA
EPREIYETATSPSPEPVLYPLGAARAQLHENYIIAQTENGLVIVDQHAAHERLVFEEMRNALHSRRPPSQVLLIPEIIDL
PEEDCDRLMDHAAGFDALGLVIERFGPGAVAVRETPAMLGEVNVQGLVRQLADEIAEWDAASTLANKLEYVAATMACHGS
VRSGRRMRPEEMNALLRQMENTPGSGQCNHGRPTYIELKLSDIERLFGRS

Nucleotide


Download         Length: 1833 bp        

>NTDB_id=368969 FY149_RS12080 WP_099086150.1 366591..368423(-) (hexB) [Agrobacterium tumefaciens strain Tul001]
ATGGCCATCAAGCAGCTTTCAGAAACCCTTATCAACCAGATCGCCGCCGGCGAGGTCATCGAGAGACCCTCCAGCGCCAC
GAAGGAACTGGTGGAAAACGCCATCGACGCTGGCGCGACCAGGATCGAGATCGCCACGGCGGGCGGCGGCAAGGGGCTGG
TGCGGATTACCGATAACGGTTCCGGCATGTCACCTGCCGACCTGGAGCTTGCGGTCAGGCGTCACTGCACCTCGAAAATT
TCCGATACGCTGGATGATATCCGCACGCTCGGGTTTCGTGGGGAGGCGCTGCCCTCCATCGGCTCTGTCGCCAAGCTGAC
GATTACCAGCCGCCAACAGGGCGCGGAACAGGGTTCGGTGATTTCCGTCACCGGCGGCAAGGTTTCCGATGTCCGGCCCG
CCGCCTCGAATGCCGGTACAATCGTCGAGGTGCGCGACCTGTTTTTCGCCACCCCCGCGCGGCTGAAATTCCTGAAGACG
GAACGGGCCGAGGCGGCCGCGATTACCGAAGTCGTCAAGCGCATGGCGATCGCCTTCCCGCATATCCGTTTCGTGCTATC
AGGCACCGACCGTTCGACGCTCGAAATTCCTTCGACCGGCGACGATCATCTGGCCCGCATGGCGCAGATTCTGGGTGCCG
AGTTCAAGGACAACGCCATCGAGATCGATGCCGGGCGCGAGGATGTGACGCTGACCGGTTTTGCCGGTGTTCCGACCTTC
AATCGCGGCAACTCGGCGCATCAATATGTCTTCGTCAATGGCCGCCCGGTGCAGGACAAGCTGCTTTTATCCGCCATTCG
CGGCGCTTATGCCGAAACCGTGCCGCATGGGCGATATCCGGTCGCGGTGCTGTCCATCACGCTTGACCCCGCCTTTGTGG
ATGTGAACGTGCATCCGGCGAAATCCGACGTGCGTTTTCGTGATCCCGGCCTCATTCGCGGGCTGATCGTCGGCGCGATC
CGCCAGGCGCTGACGCGCGACGGCGACAGGGCCGCGACGACGGGCGCGAGCCAGATGATGAATGCGTTCCGCCCCGGCTA
TAGCCCGTCCGGCATCAGGCCCTCGCCTTCCATGGCAGCAGCCGCGCCGTGGTCCGCCGCCACCTCACCGTCGCGGCCGC
TTGCGGTTTCCGGGGACATGCAATTTGCCGAGGCGGTGCAATCGCGCTTTTCCGACATCACCATGCCGACGGCGCGGGCC
GAGCCTCGGGAGATCTACGAGACCGCCACGAGCCCCTCGCCGGAACCCGTGCTTTACCCGCTCGGCGCTGCGCGGGCGCA
GCTGCACGAGAACTACATCATCGCCCAGACGGAAAACGGCCTTGTCATCGTCGACCAGCATGCCGCGCATGAGCGGCTGG
TGTTTGAGGAAATGCGCAATGCACTGCATTCCCGGCGTCCGCCGTCGCAGGTGCTGCTCATCCCTGAAATCATCGATTTG
CCGGAAGAGGATTGCGACCGGCTGATGGATCACGCCGCCGGGTTCGATGCACTAGGGCTCGTCATCGAACGTTTCGGGCC
GGGCGCGGTCGCCGTCCGGGAAACGCCTGCCATGCTGGGTGAGGTCAATGTGCAGGGGCTGGTGCGTCAGCTTGCCGACG
AGATCGCCGAATGGGACGCCGCCTCCACGCTTGCCAACAAGCTGGAATATGTCGCGGCCACCATGGCCTGCCACGGCTCG
GTGCGTTCCGGCCGGCGTATGCGGCCGGAAGAGATGAACGCGCTTCTACGGCAGATGGAAAACACGCCGGGTTCCGGTCA
ATGCAATCATGGCCGACCGACCTATATCGAACTGAAACTTTCCGATATAGAACGGCTCTTCGGCCGCAGCTGA

Domains

Predicted by InterProScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(24-122)

MutL C terminal dimerisation domain (MutL_C)

(420-566)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(208-324)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

34.003

100

0.361

Multiple sequence alignment