Detailed information NTG0368789

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FIU19_RS08950
• Genome accession: NZ_CP041010
• Coordinates: 1675612..1676655 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain FDAARGOS_766
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1670612..1681655

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FIU19_RS08920 (FIU19_08915)	-	1671030..1672286 (-)	1257	WP_001795438.1	aminopeptidase	-
FIU19_RS08925 (FIU19_08920)	-	1672289..1672489 (-)	201	WP_000180461.1	DUF1128 family protein	-
FIU19_RS08930 (FIU19_08925)	-	1672636..1673100 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FIU19_RS08935 (FIU19_08930)	-	1673107..1673382 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FIU19_RS08940 (FIU19_08935)	-	1673660..1674877 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
FIU19_RS08945 (FIU19_08940)	vraR	1674993..1675622 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
FIU19_RS08950 (FIU19_08945)	vraS	1675612..1676655 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FIU19_RS08955 (FIU19_08950)	liaF	1676652..1677353 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FIU19_RS08960 (FIU19_08955)	-	1677368..1677754 (-)	387	WP_001110179.1	hypothetical protein	-
FIU19_RS08965 (FIU19_08960)	map	1677971..1678729 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FIU19_RS08970 (FIU19_08965)	-	1679257..1680243 (+)	987	WP_000999713.1	FUSC family protein	-
FIU19_RS08975 (FIU19_08970)	-	1680674..1681087 (-)	414	WP_001549145.1	hypothetical protein	-
FIU19_RS08980 (FIU19_08975)	-	1681116..1681226 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=368789 FIU19_RS08950 WP_001017131.1 1675612..1676655(-) (vraS) [Staphylococcus aureus strain FDAARGOS_766]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=368789 FIU19_RS08950 WP_001017131.1 1675612..1676655(-) (vraS) [Staphylococcus aureus strain FDAARGOS_766]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1