Detailed information NTG0036878

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: SAA6159_RS13065
• Genome accession: NC_017338
• Coordinates: 2631454..2633562 (+)
• Length: 702 a.a.
• NCBI ID: WP_001063335.1
• Uniprot ID: -
• Organism: Staphylococcus aureus subsp. aureus JKD6159
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2626454..2638562

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SAA6159_RS13040 (SAA6159_02439)	-	2626520..2626738 (+)	219	WP_000011686.1	sterile alpha motif-like domain-containing protein	-
SAA6159_RS13045 (SAA6159_02440)	-	2627128..2627559 (+)	432	WP_000455861.1	CHAP domain-containing protein	-
SAA6159_RS13050 (SAA6159_02441)	-	2627699..2628979 (-)	1281	WP_001180322.1	hydroxymethylglutaryl-CoA reductase, degradative	-
SAA6159_RS13055 (SAA6159_02442)	-	2629233..2630399 (+)	1167	WP_000151987.1	hydroxymethylglutaryl-CoA synthase	-
SAA6159_RS13060 (SAA6159_02443)	-	2630570..2631091 (-)	522	WP_000262595.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
SAA6159_RS13065 (SAA6159_02444)	clpE	2631454..2633562 (+)	2109	WP_001063335.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
SAA6159_RS13070 (SAA6159_02445)	-	2633629..2633799 (-)	171	WP_000111367.1	FeoB-associated Cys-rich membrane protein	-
SAA6159_RS13075 (SAA6159_02446)	feoB	2633812..2635806 (-)	1995	WP_000432890.1	ferrous iron transport protein B	-
SAA6159_RS13080 (SAA6159_02447)	-	2635818..2636045 (-)	228	WP_000932073.1	FeoA family protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78194.80 Da
• Isoelectric Point: 4.7188

>NTDB_id=36878 SAA6159_RS13065 WP_001063335.1 2631454..2633562(+) (clpE) [Staphylococcus aureus subsp. aureus JKD6159]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELAQFTQQGGNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDGLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNTVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFEEHHQVKLPDDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAIDKVATEKRISELEHDKRKAVSAEKYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDANDIERLKNISSRLRSKIIGQDKAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNTIIICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRDKITDYYLDHTDVKHVDLDIEDNELLVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=36878 SAA6159_RS13065 WP_001063335.1 2631454..2633562(+) (clpE) [Staphylococcus aureus subsp. aureus JKD6159]
ATGAATAACAATTTTTTCAATAGTGACTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTAGCACAATTTACGCAACAAGGTGGTAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACGGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAACGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCGTCGCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATACTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGAAACAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTGCTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGTATTCGCGAAAAATTCGAAGAACACCATCAAGTCAAATTACCAGATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCTTATTACCTGACAAAGCAATCGATGTATTAGATATTACAGCT
GCACATTTATCTGCACAAAGCCCTGCTATTGATAAAGTCGCGACTGAAAAACGTATTTCTGAATTGGAACATGATAAACG
TAAAGCTGTAAGTGCTGAAAAATATAAAAAAGCAGATGACATTCAAAATGAAATCAAATCTCTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCAGTAGCAACGGTGCATGATATTTCTGATACCATTCAACGATTAACTGGTATTCCTGTA
TCTCAAATGGATGCCAATGACATTGAACGTTTAAAAAATATTTCTAGTCGTTTAAGAAGTAAAATCATCGGTCAAGATAA
AGCTGTAGAAATGGTTTCTCGTGCCATTCGTCGTAATCGAGCTGGTTTTGATGATGGCAATCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAAGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTACAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACACAATCATTATTTGTACGTCAAATGCTGGATTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGCCCTGAATTTCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AATCACTACAGGAAATCATTAATTTATTGTTGGATGATGTACAAGTTACATTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAATTAGGTGCGCGTCCATTAAGACGCATTGTTGA
ACAACAAGTGCGTGACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ACGAATTACTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (264-363)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	48.331	89.601	0.433
clpE	Streptococcus pneumoniae Rx1	47.326	87.892	0.416
clpE	Streptococcus pneumoniae D39	47.326	87.892	0.416
clpE	Streptococcus pneumoniae R6	47.326	87.892	0.416
clpE	Streptococcus pneumoniae TIGR4	47.326	87.892	0.416
clpC	Lactococcus lactis subsp. cremoris KW2	46.044	90.028	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	43.731	93.162	0.407
clpC	Streptococcus thermophilus LMD-9	44.64	89.031	0.397
clpC	Streptococcus thermophilus LMG 18311	44.48	89.031	0.396
clpC	Streptococcus pneumoniae TIGR4	43.77	89.174	0.39
clpC	Streptococcus pneumoniae Rx1	43.77	89.174	0.39
clpC	Streptococcus pneumoniae D39	43.77	89.174	0.39
clpC	Streptococcus mutans UA159	43.74	87.607	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	42.215	88.746	0.375