Detailed information NTG0368530

Bioinformatically predicted

Overview

• Name: ciaR
• Type: Regulator
• Locus tag: SSPS47_RS23775
• Genome accession: NZ_CP048397
• Coordinates: 5294148..5294810 (+)
• Length: 220 a.a.
• NCBI ID: WP_164252800.1
• Uniprot ID: -
• Organism: Streptomyces sp. S4.7
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 5289148..5299810

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SSPS47_RS23755 (SSPS47_24035)	mce	5290078..5290515 (-)	438	WP_164252797.1	methylmalonyl-CoA epimerase	-
SSPS47_RS23760 (SSPS47_24040)	-	5290657..5291859 (+)	1203	WP_164252798.1	acetyl-CoA C-acetyltransferase	-
SSPS47_RS23765 (SSPS47_24045)	meaB	5291941..5292900 (+)	960	WP_147873811.1	methylmalonyl Co-A mutase-associated GTPase MeaB	-
SSPS47_RS23770 (SSPS47_24050)	-	5293275..5294033 (-)	759	WP_164252799.1	PepSY domain-containing protein	-
SSPS47_RS23775 (SSPS47_24055)	ciaR	5294148..5294810 (+)	663	WP_164252800.1	response regulator transcription factor	Regulator
SSPS47_RS23780 (SSPS47_24060)	-	5294807..5296435 (+)	1629	WP_164252801.1	HAMP domain-containing sensor histidine kinase	-
SSPS47_RS23785 (SSPS47_24065)	-	5296385..5296861 (-)	477	WP_164252802.1	MarR family transcriptional regulator	-
SSPS47_RS23790 (SSPS47_24070)	-	5296996..5297772 (-)	777	WP_164252803.1	AIM24 family protein	-
SSPS47_RS23795 (SSPS47_24075)	-	5297769..5298419 (-)	651	WP_147873805.1	AIM24 family protein	-
SSPS47_RS23800 (SSPS47_24080)	-	5298419..5299057 (-)	639	WP_203557911.1	AIM24 family protein	-
SSPS47_RS23805 (SSPS47_24085)	-	5299225..5299569 (+)	345	WP_147873804.1	DUF3817 domain-containing protein	-

Sequence

Protein

• Length: 220 a.a.
• Molecular weight: 23786.45 Da
• Isoelectric Point: 5.7144

>NTDB_id=368530 SSPS47_RS23775 WP_164252800.1 5294148..5294810(+) (ciaR) [Streptomyces sp. S4.7]
MRLLIVEDEKRLAVSLAKGLRAEGFAVDVVHDGLEGLHLAGEGAYDLIVLDIMLPGMNGYRLCAALRAAGNDVPILMLTA
KDGEYDEAEGLDTGADDYLTKPFSYVVLVARVKALLRRRGSAGASPVLRVGTLSVDTATRRVHRGDTEITLTAKEFAVLE
QLAIRAGQVVGKPEILEHVWDFAYDGDPNIIEVYISALRRKLGATTIQTVRGAGYRLVAV

Nucleotide

• Length: 663 bp

>NTDB_id=368530 SSPS47_RS23775 WP_164252800.1 5294148..5294810(+) (ciaR) [Streptomyces sp. S4.7]
ATGCGCCTGTTGATTGTTGAGGACGAGAAGCGGCTCGCGGTGTCGCTGGCCAAGGGCCTGCGGGCCGAGGGCTTCGCCGT
GGACGTCGTGCACGACGGCCTCGAAGGGCTCCATCTGGCCGGTGAGGGCGCGTACGACCTGATCGTGCTCGACATCATGC
TGCCCGGCATGAACGGCTACCGCCTCTGCGCCGCCCTGCGCGCCGCCGGCAACGACGTACCGATCCTGATGCTGACGGCC
AAGGACGGCGAGTACGACGAGGCCGAGGGCCTGGACACCGGCGCCGACGACTATCTGACCAAGCCGTTCTCGTACGTCGT
GCTCGTCGCGCGGGTCAAGGCGCTCCTGCGCCGCAGGGGTTCCGCCGGGGCCTCGCCCGTTCTGCGCGTCGGCACACTCA
GCGTCGACACCGCGACCCGGCGCGTCCACCGGGGGGACACCGAGATCACCCTCACCGCCAAGGAGTTCGCGGTGCTGGAG
CAGCTCGCGATCCGGGCGGGACAGGTCGTCGGCAAGCCCGAGATCCTGGAGCACGTCTGGGACTTCGCGTACGACGGCGA
CCCCAACATCATCGAGGTCTACATCAGCGCGCTGCGCCGCAAGCTCGGCGCCACGACGATCCAGACGGTGCGCGGCGCCG
GATACCGGCTGGTCGCCGTATGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-217)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
covR	Streptococcus salivarius strain HSISS4	41.441	100	0.418
ciaR	Streptococcus mutans UA159	41.441	100	0.418
vicR	Streptococcus mutans UA159	38.696	100	0.405
covR	Lactococcus lactis subsp. lactis strain DGCC12653	40.271	100	0.405
ciaR	Streptococcus pneumoniae D39	39.64	100	0.4
ciaR	Streptococcus pneumoniae Rx1	39.64	100	0.4
ciaR	Streptococcus pneumoniae R6	39.64	100	0.4
ciaR	Streptococcus pneumoniae TIGR4	39.64	100	0.4
micA	Streptococcus pneumoniae Cp1015	37.991	100	0.395