Detailed information NTG0367235

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: FDP16_RS08585
• Genome accession: NZ_CP040798
• Coordinates: 1724426..1725469 (-)
• Length: 347 a.a.
• NCBI ID: WP_176799333.1
• Uniprot ID: A0A7H8V2C4
• Organism: Streptococcus sanguinis strain CGMH058
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1719426..1730469

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FDP16_RS08565 (FDP16_08925)	trpB	1720356..1721537 (-)	1182	WP_002929642.1	tryptophan synthase subunit beta	-
FDP16_RS08570 (FDP16_08930)	-	1721928..1722443 (-)	516	WP_176799331.1	VanZ family protein	-
FDP16_RS08575 (FDP16_08935)	rlmN	1722430..1723518 (-)	1089	WP_176799332.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
FDP16_RS08580 (FDP16_08940)	-	1723515..1724096 (-)	582	WP_002921990.1	YutD-like domain-containing protein	-
FDP16_RS08585 (FDP16_08945)	sepM	1724426..1725469 (-)	1044	WP_176799333.1	SepM family pheromone-processing serine protease	Regulator
FDP16_RS08590 (FDP16_08950)	coaD	1725456..1725950 (-)	495	WP_176799334.1	pantetheine-phosphate adenylyltransferase	-
FDP16_RS08595 (FDP16_08955)	rsmD	1725940..1726488 (-)	549	WP_176799335.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
FDP16_RS08600 (FDP16_08960)	-	1726559..1727047 (-)	489	WP_176799336.1	YcxB family protein	-
FDP16_RS08605 (FDP16_08965)	-	1727190..1727867 (+)	678	WP_176799337.1	XRE family transcriptional regulator	-
FDP16_RS08610 (FDP16_08970)	-	1727871..1729286 (+)	1416	WP_176799338.1	Y-family DNA polymerase	-
FDP16_RS08615 (FDP16_08975)	-	1729283..1729654 (+)	372	WP_176799339.1	hypothetical protein	-
FDP16_RS08620 (FDP16_08980)	-	1729635..1729925 (+)	291	WP_176799340.1	DUF5960 family protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 37866.12 Da
• Isoelectric Point: 5.0223

>NTDB_id=367235 FDP16_RS08585 WP_176799333.1 1724426..1725469(-) (sepM) [Streptococcus sanguinis strain CGMH058]
MKRIKKFILPTVIGVTIVLFLAALCVRLPYYIEVPGGAEDVRQVLLVDNKADKEAGSYNFVTVGVEQATFAHLVYAWLTP
FTDIYSAKDMTGGSTDDEFNRINQFYMETSQNMAKYQGLTTAGKEIKMDYLGVYVLQVADNSTFKGVLNIADTVTGVNDK
TFESSEELVKYVNSQKLGDKVKVTFQEDGQEKSATGKIIKLENGKNGIGISLIDRTEVSSNIPITFSTEGIGGPSAGLMF
SLAIYTQLADPTLRDGRDIAGTGSISREGEVGEIGGIDKKVVSAAQSGADIFFAPNNELTEEEKKLSPNGKNNYQTALET
AKKIKTDMKIVPVKTLQDAIDYLKKNK

Nucleotide

• Length: 1044 bp

>NTDB_id=367235 FDP16_RS08585 WP_176799333.1 1724426..1725469(-) (sepM) [Streptococcus sanguinis strain CGMH058]
ATGAAAAGAATTAAGAAGTTTATATTGCCGACGGTCATTGGCGTCACTATTGTACTTTTTCTAGCAGCTCTTTGCGTTCG
TCTGCCTTATTATATAGAAGTTCCTGGTGGTGCCGAGGATGTTCGGCAGGTCTTGCTGGTTGATAATAAGGCTGACAAGG
AAGCGGGCTCCTACAACTTTGTCACGGTCGGAGTAGAGCAGGCAACCTTTGCTCATCTGGTCTATGCTTGGCTAACCCCT
TTTACAGATATTTATTCCGCTAAGGATATGACAGGTGGCTCCACGGACGATGAGTTTAATCGGATCAACCAGTTTTACAT
GGAAACATCGCAAAACATGGCCAAATATCAGGGGTTGACGACGGCCGGTAAAGAGATTAAAATGGACTATTTGGGGGTTT
ATGTCCTGCAGGTAGCTGATAACTCAACCTTCAAAGGAGTTCTCAATATTGCTGATACGGTAACTGGTGTCAATGATAAG
ACATTTGAAAGCTCTGAAGAGCTGGTCAAGTATGTCAACTCGCAGAAGCTTGGGGATAAGGTCAAGGTGACTTTCCAAGA
AGATGGTCAGGAGAAATCAGCAACTGGAAAGATTATCAAGCTAGAGAACGGCAAGAACGGGATTGGGATTAGTCTGATAG
ACAGGACGGAAGTCAGCAGTAATATTCCGATTACATTTTCAACTGAGGGTATCGGCGGTCCTAGTGCTGGCCTTATGTTC
AGTCTAGCCATTTATACCCAGTTGGCTGATCCGACTCTTCGTGACGGCCGCGATATTGCAGGGACCGGCAGCATCAGCCG
CGAAGGTGAAGTTGGCGAAATCGGCGGAATCGATAAGAAAGTCGTTTCAGCGGCCCAAAGCGGAGCAGATATCTTCTTTG
CACCGAACAATGAACTTACAGAGGAAGAGAAGAAACTTTCTCCTAATGGGAAAAACAACTACCAAACGGCTCTGGAGACA
GCCAAGAAGATTAAAACGGATATGAAAATTGTTCCAGTTAAAACGCTGCAGGATGCCATTGACTATCTGAAAAAGAACAA
GTAA

Domains

Predicted by InterproScan.

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (232-300)

• PDZ domain (PDZ_2) (128-195)

3D structure

• AlphaFold DB: A0A7H8V2C4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	58.382	99.712	0.582