Detailed information NTG0367233

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: FDP16_RS08385
• Genome accession: NZ_CP040798
• Coordinates: 1685946..1688216 (+)
• Length: 756 a.a.
• NCBI ID: WP_176799302.1
• Uniprot ID: -
• Organism: Streptococcus sanguinis strain CGMH058
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1680946..1693216

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FDP16_RS08355 (FDP16_08700)	-	1681009..1681221 (-)	213	WP_002896137.1	exodeoxyribonuclease VII small subunit	-
FDP16_RS08360 (FDP16_08705)	xseA	1681199..1682537 (-)	1339	Protein_1635	exodeoxyribonuclease VII large subunit	-
FDP16_RS12075 (FDP16_08710)	-	1682503..1682717 (-)	215	Protein_1636	initiator RepB protein	-
FDP16_RS08365 (FDP16_08715)	-	1682693..1683535 (-)	843	WP_176799299.1	NAD(P)H-hydrate dehydratase	-
FDP16_RS08370 (FDP16_08720)	-	1683646..1684416 (-)	771	WP_176799300.1	HAD hydrolase family protein	-
FDP16_RS08375 (FDP16_08725)	-	1684413..1685267 (-)	855	WP_176799301.1	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	-
FDP16_RS08380 (FDP16_08730)	-	1685466..1685696 (-)	231	WP_002896146.1	DUF1797 family protein	-
FDP16_RS08385 (FDP16_08735)	clpE	1685946..1688216 (+)	2271	WP_176799302.1	ATP-dependent Clp protease ATP-binding subunit	Regulator
FDP16_RS08390 (FDP16_08740)	-	1688394..1689008 (-)	615	WP_176799303.1	GyrI-like domain-containing protein	-
FDP16_RS08395 (FDP16_08745)	-	1689068..1689967 (-)	900	WP_176799304.1	YafY family protein	-
FDP16_RS08400 (FDP16_08755)	-	1690193..1690642 (+)	450	WP_176799305.1	NUDIX hydrolase	-
FDP16_RS08405 (FDP16_08760)	-	1690710..1691012 (+)	303	WP_002919443.1	DUF1827 family protein	-
FDP16_RS08410 (FDP16_08765)	-	1691083..1692477 (-)	1395	WP_176799306.1	IS1182 family transposase	-
FDP16_RS08415 (FDP16_08770)	-	1692599..1693033 (-)	435	WP_176799307.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 756 a.a.
• Molecular weight: 83723.78 Da
• Isoelectric Point: 5.0175

>NTDB_id=367233 FDP16_RS08385 WP_176799302.1 1685946..1688216(+) (clpE) [Streptococcus sanguinis strain CGMH058]
MLCQNCKINESTIHLYTNVNGHKQQVDLCQNCYQIMKTDPEHSLFGGIANANNHGTDPIDDFFNSLSNFQQPQEPPTPPT
QSGGAYGGGGGYGSNPSKGGQPQPSPQKPKGLLEEFGINVTELARRGEIDPVIGRDEEIVRVIEILNRRTKNNPVLIGEP
GVGKTAVVEGLAQKIVDGDVPHKLQGKEVIRLDVVSLVQGTGIRGQFEERMQKLIDEIRSRQDVILFIDEIHEIVGAGSA
GDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQPVKVDEPTVEETITILKGIQKKYEDYHHVKYTDAA
IEAAALLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPKVIDQRLIEAENLKAQATRDEDFEKAAYFRDQIAKYKEL
QQTSVLDKDTPIISEKTIEHIVEQKTNIPVGDLKEKEQSQLVNLSSDLKAHVIGQDDAVDKIAKAIRRNRVGLGSPNRPI
GSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHSVAKLVGAPPGYVGYDEAGQLTERVRRNPYSLILLDE
VEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKSEASVGFGAAREGRTNSVLGELGNFFSPEFMNRF
DGIIEFQALSKDNLLQIVNLMLDDVNQRLATNDIHLDVTEKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAITDFYLEHP
SEKELKAIMTSNGKILIKSAKKTESTESVNSSQEEK

Nucleotide

• Length: 2271 bp

>NTDB_id=367233 FDP16_RS08385 WP_176799302.1 1685946..1688216(+) (clpE) [Streptococcus sanguinis strain CGMH058]
ATGCTTTGCCAAAATTGTAAAATCAATGAATCTACAATTCACCTTTATACCAACGTAAATGGCCATAAACAGCAGGTGGA
TTTGTGCCAAAACTGCTATCAAATCATGAAAACAGATCCTGAACATTCCTTGTTCGGTGGAATTGCTAATGCCAACAATC
ACGGAACAGATCCTATCGATGACTTCTTCAACAGCCTCAGTAATTTTCAACAGCCTCAGGAACCGCCTACTCCTCCTACC
CAATCTGGCGGAGCCTATGGAGGCGGTGGCGGCTACGGCTCCAATCCTAGCAAGGGTGGTCAGCCTCAGCCAAGTCCGCA
AAAGCCAAAAGGCCTGCTGGAAGAGTTTGGTATCAACGTGACTGAGTTGGCTCGCCGAGGCGAGATTGATCCTGTTATTG
GCCGTGATGAAGAAATTGTCCGTGTTATTGAAATCCTCAACCGCCGCACCAAAAACAATCCTGTTCTCATAGGAGAGCCA
GGAGTCGGAAAAACAGCCGTGGTGGAAGGCTTGGCCCAGAAAATTGTTGATGGTGATGTGCCTCATAAACTCCAAGGCAA
GGAAGTTATCCGCCTAGACGTTGTCAGCTTAGTACAGGGAACTGGTATCCGTGGCCAATTTGAGGAACGGATGCAGAAGC
TCATTGATGAGATTCGTTCTCGTCAGGATGTCATTCTATTCATTGATGAAATCCATGAAATTGTCGGAGCAGGCTCTGCT
GGCGATGGCAATATGGACGCTGGGAATATTCTCAAACCAGCTCTGGCTCGCGGAGAACTCCAGATGGTCGGAGCAACCAC
CCTCAATGAATACCGTATCATTGAGAAAGATGCAGCACTGGAGCGCCGGATGCAGCCAGTTAAGGTAGACGAGCCGACTG
TTGAAGAAACCATTACCATCCTCAAAGGGATTCAGAAAAAATACGAAGACTACCATCACGTCAAGTACACAGATGCGGCC
ATTGAAGCTGCTGCGCTTCTCTCCAACCGCTACATCCAAGACCGCTTCCTGCCAGACAAGGCTATTGACCTCTTGGATGA
GGCTGGATCCAAGATGAATCTAACCCTCAACTTTGTTGATCCCAAGGTCATTGACCAGCGTCTGATTGAGGCCGAAAACC
TCAAAGCTCAGGCGACTCGTGACGAAGACTTCGAGAAGGCGGCTTACTTCCGGGACCAGATTGCCAAGTACAAGGAACTG
CAGCAGACAAGTGTGCTAGACAAGGATACTCCGATTATCAGCGAGAAAACGATTGAGCACATCGTCGAGCAAAAGACCAA
TATCCCAGTTGGCGACCTCAAAGAAAAAGAACAGTCTCAACTAGTTAATCTCTCTAGTGACCTAAAGGCCCATGTCATCG
GTCAAGACGATGCTGTGGATAAGATTGCCAAGGCCATCCGCCGCAACCGAGTTGGACTAGGAAGTCCTAATCGCCCAATC
GGCAGCTTCCTCTTTGTCGGACCTACTGGTGTCGGTAAGACTGAGCTGTCTAAGCAACTAGCCATTGAGCTCTTTGGCTC
AGCTGACAGCATGATTCGCTTTGATATGAGTGAATATATGGAAAAACACAGCGTGGCCAAACTGGTCGGTGCCCCTCCGG
GCTATGTCGGCTATGATGAAGCTGGTCAATTGACTGAGCGCGTTCGCCGCAATCCTTATTCACTCATTCTGCTGGATGAG
GTAGAAAAGGCCCATCCCGATGTTATGCACATGTTCCTGCAGGTTCTAGATGATGGTCGACTGACCGATGGTCAAGGCCG
GACTGTCAGCTTCAAAGACACCATTATCATCATGACATCCAATGCCGGAACTGGCAAATCTGAAGCCAGCGTTGGCTTTG
GAGCAGCGCGTGAAGGCCGCACCAATTCCGTTTTGGGTGAATTAGGCAACTTCTTCAGTCCTGAATTTATGAACCGCTTT
GACGGCATTATCGAATTCCAGGCGCTTAGCAAGGACAATCTACTGCAAATCGTTAACCTGATGCTAGACGATGTCAACCA
ACGTTTGGCAACCAACGACATTCATCTGGATGTTACGGAGAAGGTCAAAGAAAAATTGGTTGATTTGGGCTACGATCCGA
AAATGGGGGCTCGCCCACTGCGCCGTACCATTCAGGACCATATCGAAGATGCTATTACTGACTTTTATCTGGAACATCCA
AGCGAAAAAGAGCTCAAAGCTATCATGACCAGCAATGGTAAGATTCTCATCAAGTCAGCCAAGAAAACTGAAAGCACAGA
GTCGGTTAATTCATCACAAGAAGAAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (649-723)

• ATPase family associated with various cellular activities (AAA) (AAA) (155-274)

• AAA domain (Cdc48 subfamily) (AAA_2) (478-641)

• AAA lid domain (AAA_lid_9) (293-390)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus pneumoniae Rx1	86.262	100	0.864
clpE	Streptococcus pneumoniae D39	86.262	100	0.864
clpE	Streptococcus pneumoniae R6	86.262	100	0.864
clpE	Streptococcus pneumoniae TIGR4	86.129	100	0.862
clpE	Streptococcus mutans UA159	84.238	99.868	0.841
clpC	Lactococcus lactis subsp. cremoris KW2	76.76	99.603	0.765
clpC	Bacillus subtilis subsp. subtilis str. 168	48.821	95.37	0.466
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	47.846	85.979	0.411
clpC	Streptococcus pneumoniae Rx1	48.631	82.143	0.399
clpC	Streptococcus pneumoniae D39	48.631	82.143	0.399
clpC	Streptococcus pneumoniae TIGR4	48.47	82.143	0.398
clpC	Streptococcus thermophilus LMD-9	47.444	82.804	0.393
clpC	Streptococcus thermophilus LMG 18311	47.125	82.804	0.39
clpC	Streptococcus mutans UA159	46.965	82.804	0.389