Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpC   Type   Regulator
Locus tag   FDP16_RS00945 Genome accession   NZ_CP040798
Coordinates   172138..174567 (+) Length   809 a.a.
NCBI ID   WP_176798236.1    Uniprot ID   A0A7H8UYP0
Organism   Streptococcus sanguinis strain CGMH058     
Function   degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 167138..179567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FDP16_RS00910 - 167556..167738 (-) 183 Protein_160 hypothetical protein -
  FDP16_RS00915 (FDP16_00935) - 167832..168524 (-) 693 WP_176799750.1 hypothetical protein -
  FDP16_RS00925 (FDP16_00945) rpsB 169036..169818 (+) 783 WP_002894015.1 30S ribosomal protein S2 -
  FDP16_RS00930 (FDP16_00950) tsf 169890..170933 (+) 1044 WP_002928238.1 translation elongation factor Ts -
  FDP16_RS00935 (FDP16_00955) - 171038..171388 (-) 351 WP_256254334.1 hypothetical protein -
  FDP16_RS00940 (FDP16_00960) - 171673..172137 (+) 465 WP_061592440.1 CtsR family transcriptional regulator -
  FDP16_RS00945 (FDP16_00965) clpC 172138..174567 (+) 2430 WP_176798236.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  FDP16_RS00950 (FDP16_00970) - 174648..175391 (+) 744 WP_176798237.1 DUF4272 domain-containing protein -
  FDP16_RS00955 (FDP16_00975) - 175434..175919 (+) 486 WP_164549532.1 ECF transporter S component -
  FDP16_RS00960 (FDP16_00980) - 175903..176304 (+) 402 WP_176798238.1 DUF4430 domain-containing protein -
  FDP16_RS00965 (FDP16_00985) - 176489..177547 (+) 1059 WP_176798239.1 AAA family ATPase -
  FDP16_RS00970 (FDP16_00990) pnuC 177569..178384 (+) 816 WP_176798240.1 nicotinamide riboside transporter PnuC -
  FDP16_RS00975 (FDP16_00995) - 178441..179223 (+) 783 WP_176798241.1 NUDIX hydrolase -

Sequence

Protein


Download         Length: 809 a.a.        Molecular weight: 89762.47 Da        Isoelectric Point: 5.3151

>NTDB_id=367195 FDP16_RS00945 WP_176798236.1 172138..174567(+) (clpC) [Streptococcus sanguinis strain CGMH058]
MKYSKALIESLEAAQLLAGHFPTDYLESWHLLIALANNPYSVAGSVLNEFPVEVDGFEEAAFQITGQAYQKDGHFELLPF
SYRLEELFEEAGQIAEAVRAKHVGTEHVLLAMLFDRGTLASRILEFTGFSYEDKEQGLKISDLRKVLEQRAGWGKEDIKA
IRSLNKGVMAAKQTMANMMGMPASTSGGLEDYTRDLTELARDGRLEPVIGRDQEISRIVQILSRKTKNNPVLVGDAGVGK
TALALGLAQRVAAGQVPAELAKMRVLELDLMNVVAGTRFRGDFEERMNNIINDIEEDGHVILFIDELHTIMGSGSGIDST
LDAANILKPALARGTLRTVGATTQEEYQKHIEKDAALSRRFAKVSIEEPNVADSIAILQGLRKSYEDHHKVQISDQAIET
AVKYAHRYLTSKHLPDSAIDLLDEASATVQNRGPQNYEQSDLTPVDQALMAVDFKKVSKLLKQEQQPKLYKLKVEEDDVL
ATLSTLSGIPVQKLTQTDAKKYLNLETELHKRVIGQDEAISAISRAIRRNQSGIRSSKRPIGSFMFLGPTGVGKTELAKA
LAESLFDDESALIRFDMSEYMEKFAASRLNGAPPGYVGYEEGGELTEKVRNRPYSVLLFDEVEKAHPDIFNVLLQVLDDG
QLTDSKGRKVDFSNTIIIMTSNLGATSLRDDKTVGFGARDIRLDQTNMEKRMLEELKKAYRPEFINRIDEKVVFHSLSAE
DMQEVVKVMVKPLIVSLAEKGIELKFQSSALKLLAQEGYDVEMGARPLRRTLQTQVEDKLSELLLTGDLTTGQTLKVGVK
AGQLKFEVA

Nucleotide


Download         Length: 2430 bp        

>NTDB_id=367195 FDP16_RS00945 WP_176798236.1 172138..174567(+) (clpC) [Streptococcus sanguinis strain CGMH058]
ATGAAATACTCAAAAGCCTTAATAGAAAGCTTGGAAGCAGCCCAGCTCTTGGCCGGCCATTTTCCGACAGATTATCTGGA
ATCATGGCATCTGCTGATTGCTCTGGCTAATAATCCCTACAGCGTTGCTGGCTCAGTCCTCAATGAATTTCCTGTGGAAG
TTGATGGATTTGAAGAAGCAGCTTTTCAGATTACTGGTCAGGCTTATCAGAAAGACGGTCACTTCGAGCTGCTGCCTTTT
TCTTATCGCTTAGAGGAGCTGTTTGAGGAAGCTGGCCAAATTGCAGAAGCTGTTCGCGCTAAGCATGTAGGTACCGAACA
TGTGCTGCTGGCCATGTTATTTGATCGAGGGACCTTGGCCTCTCGTATCCTGGAATTTACCGGCTTTAGCTACGAGGACA
AGGAGCAGGGGCTGAAAATCAGTGATTTGCGTAAGGTCTTGGAGCAGCGAGCTGGCTGGGGCAAGGAAGATATCAAGGCT
ATCCGCAGTCTGAATAAGGGAGTAATGGCTGCTAAGCAGACCATGGCTAATATGATGGGCATGCCGGCTTCTACCAGCGG
AGGTCTGGAAGACTACACCCGTGATCTGACGGAGCTGGCTAGAGATGGCCGATTGGAGCCAGTCATTGGCCGTGATCAGG
AAATTTCACGGATAGTTCAGATTCTCAGTCGCAAGACTAAAAACAATCCAGTGCTGGTTGGAGATGCTGGGGTTGGTAAG
ACAGCTCTAGCCTTAGGACTGGCTCAGCGTGTAGCAGCTGGTCAGGTTCCGGCTGAACTTGCTAAGATGCGGGTTTTGGA
GCTGGACTTGATGAATGTGGTCGCTGGCACTCGCTTTCGCGGAGACTTCGAGGAGCGGATGAACAACATCATCAATGACA
TTGAAGAAGATGGTCATGTCATTCTCTTCATCGATGAGCTGCATACTATCATGGGCTCTGGCAGCGGTATTGACTCGACC
TTGGATGCGGCCAATATCCTGAAACCGGCTCTGGCTCGCGGAACATTGCGGACAGTTGGTGCTACGACGCAGGAAGAGTA
TCAGAAACATATTGAAAAAGACGCTGCTCTTTCTCGGCGTTTTGCCAAGGTCAGCATAGAAGAGCCGAATGTGGCTGACA
GCATTGCTATTTTGCAAGGCTTGAGAAAGAGCTATGAGGACCATCACAAGGTGCAGATCAGTGATCAGGCTATCGAGACA
GCGGTCAAATATGCCCATCGCTATCTGACCAGTAAGCACCTGCCTGACTCTGCCATTGATCTTTTGGACGAGGCCAGTGC
GACAGTGCAGAATAGAGGACCGCAGAATTATGAGCAGTCGGATTTGACACCAGTGGATCAAGCCTTGATGGCAGTGGATT
TCAAAAAAGTCTCGAAGTTGCTTAAGCAAGAGCAGCAACCCAAGCTCTATAAACTGAAAGTGGAAGAAGACGATGTCTTG
GCTACTCTTAGTACTTTATCTGGGATTCCTGTGCAGAAGCTGACCCAGACCGATGCCAAGAAATACCTCAACTTGGAAAC
AGAACTGCATAAACGCGTGATTGGGCAGGACGAGGCGATTTCAGCTATCAGCCGAGCTATCCGACGAAACCAGTCTGGTA
TCCGCAGCAGCAAGCGGCCGATTGGCTCCTTTATGTTCCTAGGTCCGACAGGAGTCGGGAAGACAGAGCTAGCCAAGGCC
TTGGCCGAAAGTCTCTTTGATGACGAGTCTGCTCTCATACGATTTGATATGAGTGAGTACATGGAGAAATTCGCGGCTAG
CCGCCTCAACGGAGCGCCTCCAGGCTATGTAGGCTATGAAGAAGGAGGGGAGCTGACGGAGAAGGTGCGCAACCGACCTT
ATTCTGTCCTGCTCTTTGACGAGGTGGAAAAGGCGCATCCAGATATTTTCAATGTTCTCCTGCAGGTCTTGGATGATGGT
CAGCTGACTGACAGCAAGGGCCGCAAGGTGGACTTCTCCAACACGATTATTATCATGACCAGCAATCTGGGAGCAACCAG
TTTGCGGGATGATAAAACGGTGGGCTTTGGGGCGCGGGATATCCGCTTGGACCAGACCAATATGGAAAAACGGATGCTGG
AAGAACTCAAGAAAGCATATAGACCGGAGTTTATCAATCGTATCGATGAGAAGGTAGTCTTCCACAGCTTATCTGCAGAA
GATATGCAGGAAGTGGTCAAGGTTATGGTCAAACCGCTCATCGTCAGTCTTGCTGAAAAGGGAATTGAGCTGAAGTTTCA
GTCTAGTGCACTTAAGCTGCTGGCTCAGGAAGGATACGATGTGGAAATGGGAGCACGGCCATTGCGCCGCACTCTGCAGA
CCCAGGTGGAGGACAAGCTGTCTGAACTCCTCTTGACAGGAGATTTGACGACTGGTCAGACTCTTAAGGTCGGGGTCAAG
GCTGGCCAACTTAAGTTTGAAGTGGCCTAG

Domains

Predicted by InterproScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(717-797)

ATPase family associated with various cellular activities (AAA) (AAA)

(231-362)

AAA domain (Cdc48 subfamily) (AAA_2)

(539-710)

AAA lid domain (AAA_lid_9)

(371-459)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(100-136)

Clp amino terminal domain, pathogenicity island component (Clp_N)

(23-60)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7H8UYP0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpC Streptococcus pneumoniae Rx1

77.531

100

0.776
  clpC Streptococcus pneumoniae D39

77.531

100

0.776
  clpC Streptococcus pneumoniae TIGR4

77.531

100

0.776
  clpC Streptococcus mutans UA159

67.936

100

0.684
  clpC Streptococcus thermophilus LMG 18311

66.79

100

0.671
  clpC Streptococcus thermophilus LMD-9

66.667

100

0.67
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

50.484

100

0.515
  clpC Bacillus subtilis subsp. subtilis str. 168

45.443

99.011

0.45
  clpE Streptococcus mutans UA159

47.89

76.143

0.365

Multiple sequence alignment