Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   HMU_RS03680 Genome accession   NC_013949
Coordinates   786779..788572 (-) Length   597 a.a.
NCBI ID   WP_013023020.1    Uniprot ID   D3UHG9
Organism   Helicobacter mustelae 12198     
Function   integration of short DNA fragment (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 781779..793572
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HMU_RS03645 (HMU06760) - 782090..782602 (-) 513 WP_013023013.1 YhcH/YjgK/YiaL family protein -
  HMU_RS03650 (HMU06770) ribA 782678..783259 (+) 582 WP_013023014.1 GTP cyclohydrolase II -
  HMU_RS03655 (HMU06780) - 783269..784501 (+) 1233 WP_013023015.1 molybdopterin molybdotransferase MoeA -
  HMU_RS03660 (HMU06790) - 784498..784719 (+) 222 WP_013023016.1 MoaD/ThiS family protein -
  HMU_RS03665 (HMU06800) - 784723..785160 (+) 438 WP_013023017.1 molybdenum cofactor biosynthesis protein MoaE -
  HMU_RS03670 (HMU06810) mog 785215..785742 (+) 528 WP_013023018.1 molybdopterin adenylyltransferase -
  HMU_RS03675 (HMU06820) moaC 785755..786228 (+) 474 WP_013023019.1 cyclic pyranopterin monophosphate synthase MoaC -
  HMU_RS03680 (HMU06830) uvrC 786779..788572 (-) 1794 WP_013023020.1 excinuclease ABC subunit UvrC Machinery gene
  HMU_RS07675 (HMU06840) - 788566..789018 (-) 453 WP_013023021.1 hypothetical protein -
  HMU_RS03690 (HMU06850) - 789126..791165 (+) 2040 WP_013023022.1 FUSC family protein -
  HMU_RS07680 (HMU06860) - 791166..791867 (+) 702 WP_013023023.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 597 a.a.        Molecular weight: 68918.97 Da        Isoelectric Point: 10.1053

>NTDB_id=36705 HMU_RS03680 WP_013023020.1 786779..788572(-) (uvrC) [Helicobacter mustelae 12198]
MLDPKILQNLPTTFGVYQYFDANGKLLYVGKAKNIKKRVKSYFRIFENTLIPNPTASTRIKLMLSQVSHIHTMVVSSEQD
ALLLENSMIKQLKPKYNILLRDDKTYPYIVIDLEEDFPSISITRKIQDQKSLRYFGPYPSGGRDILDSLQDLLPLVQKKS
CVKGKKACLFYQIQKCPAPCENKISKDAYALTIKQAIKILQNKKLLLSLIEQKMLSLSQNLLFEEAQIYKNRLQKIKELS
SFSEISAQKPYDLDIISAIKEPHKNGYIAILVKLFMRNGKIIAADSKRVRSDYDIDIQSLFTQYLLSHYKHKLPLLPQAI
LVSEELEDVQGLQNFLQDTQGRKIPISVPKSGFKKNLIHIGIKNARELLRQEANLCASDILIQIKESFALSQTPFRIEVF
DTSHHAMSFNVGGMIVYDMQNFDPSSYRHYNLQSKDEYAQMREMLLHRIESFVKSPPPNLWVIDGGRAQLNLAQNLLESA
GYDIDILAISKEKRDHKAYRAKGYARDRIYTKERDLRLDPSDKRLQFLQKLRDESHRFAIKFHRSQKTKNLTKNLPYTTA
EQKRLLQYFGDFAKLQSASAQEISQVLRNKPSKKTQG

Nucleotide


Download         Length: 1794 bp        

>NTDB_id=36705 HMU_RS03680 WP_013023020.1 786779..788572(-) (uvrC) [Helicobacter mustelae 12198]
ATGCTAGATCCCAAAATCCTGCAAAATCTCCCCACCACCTTTGGGGTCTATCAGTATTTTGATGCCAATGGCAAGCTACT
GTATGTAGGCAAGGCAAAAAATATCAAAAAACGCGTGAAGAGCTATTTTCGCATTTTTGAAAACACCCTCATCCCCAATC
CCACCGCAAGCACGCGCATCAAGCTCATGCTCTCCCAAGTCTCACACATCCATACCATGGTGGTATCTAGCGAGCAAGAC
GCACTGCTCTTAGAAAATTCCATGATTAAACAGCTCAAACCCAAATACAATATTCTCCTTCGCGATGACAAAACCTATCC
CTACATTGTCATAGATCTTGAGGAAGATTTCCCCAGCATCTCCATCACGCGCAAGATCCAAGATCAAAAATCCCTGCGCT
ATTTTGGCCCCTATCCCAGCGGTGGGCGCGATATTTTGGACAGTCTGCAGGATCTCCTGCCTCTGGTACAAAAAAAATCC
TGTGTCAAGGGCAAAAAAGCCTGTCTTTTTTATCAGATCCAAAAATGCCCAGCCCCTTGTGAAAATAAAATCAGCAAAGA
TGCCTACGCGCTGACTATCAAGCAGGCCATAAAGATACTGCAAAACAAAAAACTCCTACTGTCTTTAATCGAGCAAAAAA
TGCTTTCTTTGTCACAAAATCTCCTCTTTGAAGAAGCCCAGATTTACAAAAACCGCCTGCAAAAAATCAAAGAATTAAGC
AGCTTTTCTGAGATTTCTGCCCAAAAGCCCTATGATCTTGACATCATTAGCGCAATCAAAGAGCCACACAAAAATGGCTA
CATCGCGATCCTAGTGAAGCTTTTCATGCGCAATGGCAAAATCATCGCCGCAGATTCCAAGCGTGTGCGCAGTGATTATG
ACATTGATATCCAATCCCTCTTCACCCAATACCTACTCTCGCATTACAAACACAAGCTCCCCCTACTCCCGCAAGCAATT
TTAGTCTCTGAAGAGCTAGAAGATGTGCAGGGTTTGCAAAATTTCCTCCAAGATACCCAGGGCAGAAAAATCCCTATCTC
CGTGCCAAAATCAGGCTTCAAAAAAAATCTCATTCACATTGGCATCAAAAATGCAAGAGAGCTCCTACGCCAGGAGGCAA
ATCTCTGTGCTAGCGATATTCTCATCCAAATCAAAGAATCCTTTGCTCTCTCTCAAACTCCCTTTCGCATCGAGGTTTTT
GACACGAGTCATCATGCCATGAGCTTCAATGTAGGGGGCATGATCGTCTATGACATGCAAAATTTTGACCCCTCCTCCTA
TCGGCACTACAATCTCCAATCCAAAGATGAATACGCCCAAATGCGTGAAATGCTCCTACATCGCATTGAGAGCTTTGTCA
AATCACCCCCGCCCAATCTCTGGGTCATTGATGGAGGCAGAGCGCAATTGAATCTAGCTCAAAATCTCCTAGAGAGTGCA
GGATATGACATCGATATCCTAGCCATCTCCAAAGAAAAAAGAGACCACAAGGCTTATCGCGCCAAGGGATATGCAAGGGA
TAGGATTTATACCAAAGAAAGGGATTTGAGGCTTGATCCCAGTGATAAGAGGCTGCAATTTTTGCAAAAACTGCGCGATG
AATCCCACCGTTTTGCTATAAAATTCCATCGCAGTCAAAAGACCAAAAATCTCACCAAAAATCTACCCTACACCACCGCA
GAACAAAAGCGACTTTTGCAATATTTTGGAGACTTTGCCAAACTCCAATCTGCCAGCGCGCAAGAAATCTCCCAAGTACT
AAGAAACAAACCCAGCAAAAAAACCCAAGGCTAG

Domains

Predicted by InterproScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(386-540)

GIY-YIG catalytic domain (GIY-YIG)

(14-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB D3UHG9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Helicobacter pylori 26695

51.695

98.827

0.511

Multiple sequence alignment