Detailed information    

insolico Bioinformatically predicted

Overview

Name   irvR   Type   Regulator
Locus tag   GWG04_RS14285 Genome accession   NZ_CP047922
Coordinates   2875233..2875940 (-) Length   235 a.a.
NCBI ID   WP_000094093.1    Uniprot ID   A0A1D4DWM6
Organism   Staphylococcus aureus strain SR231     
Function   regulate expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2870233..2880940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GWG04_RS14255 (GWG04_14305) sph 2871176..2872006 (-) 831 Protein_2790 sphingomyelin phosphodiesterase -
  GWG04_RS14260 (GWG04_14310) - 2872057..2873094 (-) 1038 WP_000857188.1 site-specific integrase -
  GWG04_RS14265 (GWG04_14315) - 2873155..2874228 (-) 1074 WP_234743860.1 Abi family protein -
  GWG04_RS14270 (GWG04_14320) - 2874526..2874693 (-) 168 WP_031806878.1 hypothetical protein -
  GWG04_RS14275 (GWG04_14325) - 2874893..2875078 (-) 186 WP_103147863.1 hypothetical protein -
  GWG04_RS14280 - 2875075..2875221 (-) 147 WP_001049401.1 hypothetical protein -
  GWG04_RS14285 (GWG04_14330) irvR 2875233..2875940 (-) 708 WP_000094093.1 XRE family transcriptional regulator Regulator
  GWG04_RS14290 (GWG04_14335) - 2876111..2876350 (+) 240 WP_000548576.1 helix-turn-helix transcriptional regulator -
  GWG04_RS14295 (GWG04_14340) - 2876363..2876623 (+) 261 WP_000435341.1 transcriptional regulator -
  GWG04_RS14300 (GWG04_14345) - 2876647..2877186 (-) 540 WP_000351243.1 hypothetical protein -
  GWG04_RS14305 (GWG04_14350) - 2877243..2877998 (+) 756 WP_001148343.1 phage antirepressor KilAC domain-containing protein -
  GWG04_RS14310 (GWG04_14355) - 2878014..2878211 (+) 198 WP_001148862.1 hypothetical protein -
  GWG04_RS14315 (GWG04_14360) - 2878198..2878578 (-) 381 WP_000762521.1 DUF2513 domain-containing protein -
  GWG04_RS14320 (GWG04_14365) - 2878633..2878953 (+) 321 WP_001120197.1 DUF771 domain-containing protein -
  GWG04_RS14325 (GWG04_14370) - 2878950..2879111 (+) 162 WP_031766022.1 DUF1270 domain-containing protein -
  GWG04_RS14330 (GWG04_14375) - 2879205..2879508 (+) 304 Protein_2805 DUF2482 family protein -
  GWG04_RS14335 (GWG04_14380) - 2879513..2879773 (+) 261 WP_000291506.1 DUF1108 family protein -
  GWG04_RS14340 (GWG04_14385) - 2879782..2880045 (+) 264 WP_001205732.1 hypothetical protein -

Sequence

Protein


Download         Length: 235 a.a.        Molecular weight: 26769.35 Da        Isoelectric Point: 5.4082

>NTDB_id=366541 GWG04_RS14285 WP_000094093.1 2875233..2875940(-) (irvR) [Staphylococcus aureus strain SR231]
MSSFSSNLERLMNKRDMSDSELAELVDVNRTTVTRWRKGIRSPKLDKLPEIANVFGVKPLDLIHDMDDSKIIEEIHNVSS
QLTPPRQSNVLKYATNQLEEQNNDSDNLVDFNSYIQEKSEVDIYGCASAGIGERLYNEPISKEFVRGYVPAHDIALKVNG
DSMEPLFKNGQIIFIEKSHTIKDGQIGVFIINGDAYVKKVYVEDNRLTLVSLNKKYKDLHFYDNESVRLVGKVIL

Nucleotide


Download         Length: 708 bp        

>NTDB_id=366541 GWG04_RS14285 WP_000094093.1 2875233..2875940(-) (irvR) [Staphylococcus aureus strain SR231]
ATGAGTTCATTTTCTTCGAATCTAGAACGTCTGATGAACAAAAGAGATATGAGTGATAGTGAATTAGCAGAATTAGTAGA
TGTAAATAGAACAACAGTCACAAGATGGAGAAAGGGAATTAGAAGTCCAAAACTAGATAAATTACCTGAAATAGCTAATG
TTTTTGGAGTTAAACCCTTAGATTTAATACATGATATGGATGATTCGAAAATTATTGAAGAAATTCATAACGTGTCATCT
CAACTCACGCCTCCAAGACAAAGCAATGTACTAAAATATGCGACTAATCAATTAGAAGAGCAAAATAATGACAGTGATAA
TCTGGTAGATTTCAATTCTTACATTCAAGAAAAATCCGAAGTGGATATATATGGTTGTGCGTCTGCTGGTATTGGTGAAA
GATTATATAACGAGCCTATTTCAAAAGAATTCGTAAGAGGTTATGTCCCCGCACATGATATAGCTTTAAAAGTAAATGGA
GACTCAATGGAGCCGTTATTTAAAAATGGACAAATTATATTCATTGAAAAATCTCACACTATCAAAGATGGACAAATAGG
CGTCTTTATTATAAATGGAGATGCTTACGTAAAGAAGGTTTATGTAGAAGATAACAGATTAACGTTGGTTTCTTTAAATA
AAAAGTATAAAGATTTACATTTTTATGATAATGAAAGTGTGAGGTTAGTTGGAAAAGTTATTTTATAG

Domains

Predicted by InterProScan.

Peptidase S24-like (Peptidase_S24)

(123-234)

Helix-turn-helix (HTH_3)

(8-61)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1D4DWM6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  irvR Streptococcus mutans UA159

30.769

100

0.374