Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   M594_RS00985 Genome accession   NZ_CP047883
Coordinates   195484..196395 (+) Length   303 a.a.
NCBI ID   WP_173875738.1    Uniprot ID   -
Organism   Streptococcus mitis strain S022-V3-A4     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 190484..201395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  M594_RS00965 (M594_00985) yajC 191215..191514 (+) 300 WP_001069289.1 preprotein translocase subunit YajC -
  M594_RS00970 (M594_00990) - 191561..192004 (+) 444 WP_173875735.1 low molecular weight protein-tyrosine-phosphatase -
  M594_RS00975 (M594_00995) - 191991..192401 (+) 411 WP_173875736.1 MORN repeat-containing protein -
  M594_RS00980 (M594_01000) adhE 192701..195352 (+) 2652 WP_173875737.1 bifunctional acetaldehyde-CoA/alcohol dehydrogenase -
  M594_RS00985 (M594_01005) comR 195484..196395 (+) 912 WP_173875738.1 helix-turn-helix domain-containing protein Regulator
  M594_RS00990 (M594_01010) - 196606..197289 (+) 684 WP_173875739.1 ABC transporter ATP-binding protein -
  M594_RS00995 (M594_01015) - 197258..198559 (+) 1302 WP_173875740.1 ABC transporter permease -
  M594_RS01000 (M594_01020) gap 198736..199743 (+) 1008 WP_000260685.1 type I glyceraldehyde-3-phosphate dehydrogenase -
  M594_RS01005 (M594_01025) - 199812..200687 (-) 876 WP_302478532.1 RluA family pseudouridine synthase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35788.13 Da        Isoelectric Point: 4.8134

>NTDB_id=366269 M594_RS00985 WP_173875738.1 195484..196395(+) (comR) [Streptococcus mitis strain S022-V3-A4]
MNDLGEKVRLLREEKGLSRPVFCGDESELSVRQLVRIEKGEFRPTIKTLEYIANRLGIPSYVLMPDYKELPKRYQELKYF
LLHHPDYGDKELQEQKEEYFDEIFECFYDDLPRDEKVLVDCLQAIDAVRATGNSLYGTSLLENGLHNLLSRDVYKAEELL
RLRLYFACNLMDGLKAGEIKESEHETILYFHDKLSSQVDKMEFDCLDLLRDSLLASLTCIEIMGLLHYFKRAVETLNKIG
QKTRDFQKQPIVLMLEWKYYIQTDYETAKQKYEEAKMMARMFGNEKLLVSLDKEWAEDLEKYC

Nucleotide


Download         Length: 912 bp        

>NTDB_id=366269 M594_RS00985 WP_173875738.1 195484..196395(+) (comR) [Streptococcus mitis strain S022-V3-A4]
ATGAATGATCTAGGGGAAAAGGTAAGACTTCTTAGAGAAGAGAAAGGACTTAGTCGCCCTGTTTTTTGTGGAGATGAGTC
AGAACTGTCAGTCCGTCAGTTAGTGCGCATTGAAAAAGGAGAATTTCGTCCTACGATAAAAACACTAGAATATATAGCGA
ATAGGTTAGGCATTCCATCTTATGTCTTGATGCCAGACTATAAGGAATTACCGAAACGTTACCAAGAATTAAAATACTTT
CTTCTTCATCATCCTGACTATGGAGACAAGGAGTTGCAGGAGCAGAAGGAAGAATATTTTGATGAGATTTTTGAATGTTT
TTATGATGATTTGCCACGTGATGAGAAAGTGCTAGTGGATTGTCTTCAAGCTATAGATGCAGTGAGAGCAACTGGTAATT
CTTTGTATGGTACCAGTTTGCTTGAAAATGGTCTGCATAACTTACTATCCAGAGATGTATATAAAGCGGAGGAACTATTA
AGACTGAGGTTGTATTTTGCATGTAACTTAATGGATGGTTTGAAAGCGGGTGAAATAAAAGAATCTGAGCATGAAACCAT
TCTTTATTTTCATGATAAACTAAGTTCTCAGGTTGATAAGATGGAGTTCGATTGTTTGGACTTACTTAGAGACTCCTTGT
TAGCTTCTTTAACTTGTATAGAGATTATGGGGTTGCTTCATTATTTTAAGAGGGCAGTCGAGACCTTAAATAAAATAGGG
CAAAAAACACGAGATTTTCAAAAACAACCGATTGTCTTGATGCTTGAGTGGAAATATTATATTCAGACGGATTATGAAAC
AGCCAAACAAAAGTATGAAGAAGCAAAAATGATGGCAAGGATGTTTGGCAATGAGAAGTTATTAGTTAGTTTAGATAAGG
AATGGGCTGAGGACCTAGAAAAGTATTGTTAA

Domains

Predicted by InterProScan.

Helix-turn-helix (HTH_3)

(9-59)

ComR tetratricopeptide (ComR_TPR)

(71-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus mutans UA159

37.874

99.34

0.376