Detailed information NTG0366236

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: FFX42_RS05060
• Genome accession: NZ_CP040665
• Coordinates: 1011925..1012911 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain D592
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1006925..1017911

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FFX42_RS05035 (FFX42_05050)	opp4B	1007139..1008101 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
FFX42_RS05040 (FFX42_05055)	opp4C	1008113..1008994 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
FFX42_RS05045 (FFX42_05060)	trpS	1009036..1010025 (-)	990	WP_130163217.1	tryptophan--tRNA ligase	-
FFX42_RS05050 (FFX42_05065)	spxA	1010319..1010714 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
FFX42_RS05055 (FFX42_05070)	mecA	1011085..1011804 (+)	720	WP_001217728.1	adaptor protein MecA	-
FFX42_RS05060 (FFX42_05075)	coiA	1011925..1012911 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
FFX42_RS05065 (FFX42_05080)	pepF	1012959..1014767 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
FFX42_RS05070 (FFX42_05085)	yjbH	1015227..1016033 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
FFX42_RS05075 (FFX42_05090)	-	1016056..1016421 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
FFX42_RS05080 (FFX42_05095)	-	1016525..1017118 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
FFX42_RS05085 (FFX42_05100)	-	1017304..1017651 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=366236 FFX42_RS05060 WP_000959282.1 1011925..1012911(+) (coiA) [Staphylococcus aureus strain D592]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=366236 FFX42_RS05060 WP_000959282.1 1011925..1012911(+) (coiA) [Staphylococcus aureus strain D592]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976