Detailed information NTG0365928

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FF959_RS13885
• Genome accession: NZ_CP040623
• Coordinates: 2717875..2718762 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain D592-HR
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2712875..2723762

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FF959_RS13850 (FF959_13855)	-	2712894..2712986 (+)	93	WP_010956583.1	hypothetical protein	-
FF959_RS13855 (FF959_13860)	-	2713094..2713591 (-)	498	WP_001065268.1	glutathione peroxidase	-
FF959_RS13860 (FF959_13865)	-	2713601..2713861 (-)	261	WP_001796813.1	hypothetical protein	-
FF959_RS13870 (FF959_13875)	-	2714243..2714356 (-)	114	Protein_2634	hypothetical protein	-
FF959_RS13875 (FF959_13880)	-	2715015..2717015 (-)	2001	WP_000776750.1	ABC transporter permease	-
FF959_RS13880 (FF959_13885)	-	2717012..2717767 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
FF959_RS13885 (FF959_13890)	braS	2717875..2718762 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FF959_RS13890 (FF959_13895)	braR	2718773..2719438 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FF959_RS13895 (FF959_13900)	-	2719464..2719664 (-)	201	WP_000604730.1	hypothetical protein	-
FF959_RS13900 (FF959_13905)	-	2719862..2721286 (+)	1425	WP_000953755.1	alkaline phosphatase	-
FF959_RS14750 (FF959_13910)	-	2721346..2721447 (-)	102	WP_000731976.1	SE2200 family small protein	-
FF959_RS13910 (FF959_13915)	-	2721569..2722024 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FF959_RS13915 (FF959_13920)	-	2722269..2723030 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=365928 FF959_RS13885 WP_000143425.1 2717875..2718762(-) (braS) [Staphylococcus aureus strain D592-HR]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=365928 FF959_RS13885 WP_000143425.1 2717875..2718762(-) (braS) [Staphylococcus aureus strain D592-HR]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1