Detailed information NTG0365251

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FA001_RS13965
• Genome accession: NZ_CP040560
• Coordinates: 2715842..2716729 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143419.1
• Uniprot ID: A0A266CLT2
• Organism: Staphylococcus aureus strain Col52-A5
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2710842..2721729

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FA001_RS13930 (FA001_13930)	-	2710862..2710954 (+)	93	WP_010956583.1	hypothetical protein	-
FA001_RS13935 (FA001_13935)	-	2711062..2711559 (-)	498	WP_001065268.1	glutathione peroxidase	-
FA001_RS13940 (FA001_13940)	-	2711569..2711829 (-)	261	WP_001789910.1	hypothetical protein	-
FA001_RS13950 (FA001_13950)	-	2712211..2712324 (-)	114	WP_001791776.1	hypothetical protein	-
FA001_RS13955 (FA001_13955)	-	2712983..2714983 (-)	2001	WP_000776751.1	ABC transporter permease	-
FA001_RS13960 (FA001_13960)	-	2714980..2715734 (-)	755	Protein_2648	ABC transporter ATP-binding protein	-
FA001_RS13965 (FA001_13965)	braS	2715842..2716729 (-)	888	WP_000143419.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FA001_RS13970 (FA001_13970)	braR	2716740..2717405 (-)	666	WP_000697886.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FA001_RS13975 (FA001_13975)	-	2717431..2717631 (-)	201	WP_000604728.1	hypothetical protein	-
FA001_RS13980 (FA001_13980)	-	2717829..2719253 (+)	1425	WP_000953744.1	alkaline phosphatase	-
FA001_RS14890 (FA001_13985)	-	2719313..2719414 (-)	102	WP_000731972.1	SE2200 family small protein	-
FA001_RS13990 (FA001_13990)	-	2719536..2719991 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FA001_RS13995 (FA001_13995)	-	2720236..2720997 (-)	762	WP_000323455.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34019.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=365251 FA001_RS13965 WP_000143419.1 2715842..2716729(-) (braS) [Staphylococcus aureus strain Col52-A5]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=365251 FA001_RS13965 WP_000143419.1 2715842..2716729(-) (braS) [Staphylococcus aureus strain Col52-A5]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTGTTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A266CLT2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.661	100	0.997