Detailed information NTG0365246

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FA001_RS09960
• Genome accession: NZ_CP040560
• Coordinates: 1974161..1975204 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain Col52-A5
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1969161..1980204

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FA001_RS09930 (FA001_09930)	-	1969579..1970835 (-)	1257	WP_001795438.1	aminopeptidase	-
FA001_RS09935 (FA001_09935)	-	1970838..1971038 (-)	201	WP_000180461.1	DUF1128 family protein	-
FA001_RS09940 (FA001_09940)	-	1971185..1971649 (+)	465	WP_000228666.1	low molecular weight protein-tyrosine-phosphatase	-
FA001_RS09945 (FA001_09945)	-	1971656..1971931 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FA001_RS09950 (FA001_09950)	-	1972209..1973426 (+)	1218	WP_000037075.1	YihY/virulence factor BrkB family protein	-
FA001_RS09955 (FA001_09955)	vraR	1973542..1974171 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
FA001_RS09960 (FA001_09960)	vraS	1974161..1975204 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FA001_RS09965 (FA001_09965)	liaF	1975201..1975902 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
FA001_RS09970 (FA001_09970)	-	1975917..1976303 (-)	387	WP_001110179.1	hypothetical protein	-
FA001_RS09975 (FA001_09975)	map	1976520..1977278 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
FA001_RS09980 (FA001_09980)	-	1977865..1978851 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
FA001_RS09990 (FA001_09990)	-	1979341..1979754 (-)	414	WP_001549145.1	hypothetical protein	-
FA001_RS09995 (FA001_09995)	-	1979783..1979893 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=365246 FA001_RS09960 WP_001017131.1 1974161..1975204(-) (vraS) [Staphylococcus aureus strain Col52-A5]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=365246 FA001_RS09960 WP_001017131.1 1974161..1975204(-) (vraS) [Staphylococcus aureus strain Col52-A5]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTTTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
TATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGATAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1