Detailed information NTG0036494

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SLGD_RS05085
• Genome accession: NC_013893
• Coordinates: 1106923..1107966 (+)
• Length: 347 a.a.
• NCBI ID: WP_002461334.1
• Uniprot ID: A0A853V5Y6
• Organism: Staphylococcus lugdunensis HKU09-01
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1101923..1112966

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SLGD_RS05060 (SLGD_01039)	-	1102213..1103574 (-)	1362	WP_002477958.1	FAD-dependent oxidoreductase	-
SLGD_RS05065 (SLGD_01040)	-	1103708..1104688 (-)	981	WP_002477959.1	FUSC family protein	-
SLGD_RS05070 (SLGD_01041)	map	1104933..1105688 (+)	756	WP_002461338.1	type I methionyl aminopeptidase	-
SLGD_RS05075 (SLGD_01042)	-	1105814..1106200 (+)	387	WP_002477960.1	hypothetical protein	-
SLGD_RS05080 (SLGD_01043)	liaF	1106225..1106926 (+)	702	WP_002461335.1	cell wall-active antibiotics response protein LiaF	-
SLGD_RS05085 (SLGD_01044)	vraS	1106923..1107966 (+)	1044	WP_002461334.1	sensor histidine kinase	Regulator
SLGD_RS05090 (SLGD_01045)	vraR	1107956..1108585 (+)	630	WP_002461333.1	two-component system response regulator VraR	Regulator
SLGD_RS05095 (SLGD_01046)	-	1108758..1109987 (-)	1230	WP_012990799.1	YihY/virulence factor BrkB family protein	-
SLGD_RS05100 (SLGD_01047)	-	1110190..1110474 (-)	285	WP_002461330.1	YtxH domain-containing protein	-
SLGD_RS05105 (SLGD_01048)	-	1110481..1110945 (-)	465	WP_002477961.1	low molecular weight protein-tyrosine-phosphatase	-
SLGD_RS05110 (SLGD_01049)	-	1111109..1111294 (+)	186	WP_002492715.1	DUF1128 domain-containing protein	-
SLGD_RS05115 (SLGD_01050)	-	1111307..1112545 (+)	1239	WP_002477963.1	aminopeptidase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 39934.41 Da
• Isoelectric Point: 5.9679

>NTDB_id=36494 SLGD_RS05085 WP_002461334.1 1106923..1107966(+) (vraS) [Staphylococcus lugdunensis HKU09-01]
MNHYIRAIGSMLILVYSLMIAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLVIILLCIIVGSILAFKINQQNDWIKT
QVEHAIEGETVGINDQNIELYNETIDLYHTLVPLNQELHRLRMKTQNLTNENYNLNDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETELEPPLDQQIPVLEKMVQDSQLEMRALLLHLRPIGLKDKSLGEGIKDLVIDLQKKVPMKVVHDI
EEFKVPKGLEDHLFRITQEAISNTLRHSKGTKVTVELFNKADYLLLRIQDNGIGFNVDDKVEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSHDN

Nucleotide

• Length: 1044 bp

>NTDB_id=36494 SLGD_RS05085 WP_002461334.1 1106923..1107966(+) (vraS) [Staphylococcus lugdunensis HKU09-01]
ATGAACCACTATATTCGAGCAATCGGCTCAATGTTGATACTAGTGTATAGCTTAATGATTGCTTTTCTGTTTATTGATAA
AGTATTCGTTAATATCATTTACTTTCAAGGCATGTTTTATACACAAATATTTGGAATACCAGTATTCCTTTTCTTAAATT
TGGTTATTATTTTATTATGTATTATTGTGGGCTCTATATTAGCTTTTAAAATCAATCAACAAAATGATTGGATCAAAACA
CAAGTAGAGCATGCAATAGAAGGGGAAACAGTTGGTATAAATGATCAAAATATAGAATTGTATAATGAAACAATTGATTT
ATATCATACATTAGTTCCCTTAAATCAAGAGTTACACCGATTAAGAATGAAAACACAAAACTTAACAAATGAAAATTATA
ATTTAAATGATGTAAAAGTGAAAAAAATAATTGAAGACGAACGTCAACGTCTAGCTCGAGAATTACATGATTCAGTGAGC
CAGCAATTATTTGCAGCCAGTATGATGTTATCTGCAATTAAAGAAACAGAGCTAGAACCACCTTTAGATCAACAAATTCC
AGTTTTAGAAAAAATGGTGCAAGATTCACAACTTGAAATGAGAGCGCTCTTATTACATCTAAGACCAATTGGTTTAAAGG
ACAAGTCGTTGGGTGAAGGTATTAAAGATTTAGTCATCGATTTACAGAAAAAAGTACCGATGAAAGTGGTTCACGATATT
GAAGAATTTAAAGTGCCTAAAGGTTTAGAAGATCATTTGTTTAGAATTACTCAAGAAGCCATCTCTAATACTTTAAGACA
TTCAAAAGGAACTAAAGTTACTGTAGAATTATTTAATAAAGCAGATTATTTATTATTAAGAATACAAGATAATGGCATTG
GATTTAATGTTGATGATAAAGTCGAACAAAGTTATGGCTTGAAAAATATGCGCGAACGTGCGTTAGAAATAGGTGCAACA
TTTCATATTGTATCATTGCCTGATTCTGGAACAAGAATAGAGGTTAAAGCACCGTTAAACAAGGAGGATTCACATGACAA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A853V5Y6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	91.066	100	0.911