Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA   Type   Machinery gene
Locus tag   BCPR1_RS06565 Genome accession   NZ_CP040515
Coordinates   1264176..1265219 (+) Length   347 a.a.
NCBI ID   WP_044793799.1    Uniprot ID   A0A5C5AMY2
Organism   Bacillus paranthracis strain PR1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1259176..1270219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BCPR1_RS06525 (BCPR1_06525) - 1259247..1259507 (+) 261 WP_000817964.1 DUF3966 domain-containing protein -
  BCPR1_RS06530 (BCPR1_06530) - 1259598..1259940 (+) 343 Protein_1251 group-specific protein -
  BCPR1_RS06535 (BCPR1_06535) - 1260020..1260508 (+) 489 WP_044793794.1 hypothetical protein -
  BCPR1_RS06540 (BCPR1_06540) - 1260545..1260856 (-) 312 WP_001080447.1 hypothetical protein -
  BCPR1_RS06545 (BCPR1_06545) - 1261111..1261326 (+) 216 WP_001008330.1 DUF3912 family protein -
  BCPR1_RS06550 (BCPR1_06550) - 1261406..1262800 (-) 1395 WP_044793796.1 L-cystine transporter -
  BCPR1_RS06555 (BCPR1_06555) - 1262907..1263149 (-) 243 WP_000440710.1 DUF2626 domain-containing protein -
  BCPR1_RS06560 (BCPR1_06560) - 1263275..1263970 (-) 696 WP_138321101.1 helix-turn-helix domain-containing protein -
  BCPR1_RS06565 (BCPR1_06565) comGA 1264176..1265219 (+) 1044 WP_044793799.1 competence protein ComGA Machinery gene
  BCPR1_RS06570 (BCPR1_06570) comGB 1265212..1266243 (+) 1032 WP_052587781.1 competence type IV pilus assembly protein ComGB -
  BCPR1_RS06575 (BCPR1_06575) comGC 1266255..1266554 (+) 300 WP_001178694.1 competence type IV pilus major pilin ComGC -
  BCPR1_RS06580 (BCPR1_06580) comGD 1266551..1267006 (+) 456 WP_000810387.1 comG operon protein ComGD -
  BCPR1_RS06585 (BCPR1_06585) comGE 1266999..1267301 (+) 303 WP_070806834.1 competence type IV pilus minor pilin ComGE -
  BCPR1_RS06590 (BCPR1_06590) comGF 1267271..1267741 (+) 471 WP_000923058.1 competence type IV pilus minor pilin ComGF -
  BCPR1_RS06595 (BCPR1_06595) comGG 1267738..1268109 (+) 372 WP_000595196.1 competence type IV pilus minor pilin ComGG -
  BCPR1_RS06600 (BCPR1_06600) - 1268285..1268935 (+) 651 WP_044793803.1 2OG-Fe(II) oxygenase -
  BCPR1_RS06605 (BCPR1_06605) - 1269055..1269552 (+) 498 WP_044793804.1 shikimate kinase -
  BCPR1_RS06610 (BCPR1_06610) - 1269591..1269791 (+) 201 WP_000106079.1 YqzE family protein -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39259.79 Da        Isoelectric Point: 9.0719

>NTDB_id=364864 BCPR1_RS06565 WP_044793799.1 1264176..1265219(+) (comGA) [Bacillus paranthracis strain PR1]
MNGIESFANMILKEACRVQASDLHIVPRQKDVVVQLRIGKDLMTKQCIEKEFGEKLVSHFKFLASMDIGERRKPQNGSLY
LQMDGQEVYLRLSTLPTVYQESLVIRLHLQASIQPLSHLSLFPSTAKKLLSFLHYSHGLLVFTGPTGSGKTTTMYALLEV
IRKKKTRRIVTLEDPVEKRNDGVLQIQINEKAGITYEAGLKAILRHDPDVILVGEIRDEETAKIAIRASLTGHLVMTTLH
TNDAKGAILRFMDFGITRQEIEQSLLAIAAQRLVELKCPFCKRKCSTVCKSMRQVRQASIYELLYGYELKQAIKEANGEC
VTYKHETLESSLRKGYALGFLEEDVYV

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=364864 BCPR1_RS06565 WP_044793799.1 1264176..1265219(+) (comGA) [Bacillus paranthracis strain PR1]
ATGAATGGAATTGAAAGCTTTGCGAATATGATTTTAAAAGAAGCGTGCAGGGTACAAGCGTCGGACTTACATATTGTGCC
CCGGCAGAAGGATGTAGTGGTTCAGTTGCGTATAGGAAAAGATTTAATGACGAAACAATGCATTGAAAAGGAGTTTGGAG
AAAAACTTGTTTCACACTTTAAATTTTTAGCATCCATGGATATAGGGGAGAGGCGGAAGCCACAAAATGGCTCACTGTAT
TTACAAATGGACGGACAAGAAGTGTATTTACGTCTTTCCACGCTTCCAACTGTATATCAAGAAAGTCTCGTTATTCGTCT
TCATTTACAAGCATCTATTCAGCCGTTATCTCATCTTTCGTTATTTCCAAGTACAGCGAAGAAACTACTTTCTTTTTTAC
ATTATTCCCATGGGTTACTCGTATTTACTGGACCGACTGGGTCGGGGAAGACAACAACAATGTATGCATTATTAGAGGTA
ATTAGAAAAAAGAAAACACGCCGCATCGTTACACTGGAAGATCCAGTTGAAAAAAGAAATGACGGTGTATTACAAATTCA
AATAAATGAAAAAGCAGGTATCACATATGAGGCGGGACTAAAGGCTATTTTGCGTCATGATCCAGATGTTATTTTAGTGG
GTGAAATTCGTGATGAAGAAACAGCAAAAATCGCTATAAGAGCAAGTTTGACTGGCCATTTAGTAATGACGACATTGCAT
ACGAACGATGCGAAAGGAGCGATACTTCGGTTTATGGACTTTGGCATAACGAGGCAAGAGATTGAACAATCTTTATTGGC
TATAGCTGCACAGCGACTTGTTGAATTGAAGTGTCCGTTTTGTAAAAGAAAGTGCTCAACTGTATGTAAATCAATGAGGC
AAGTAAGGCAAGCGAGTATTTATGAGTTGTTATATGGATATGAGTTAAAACAAGCGATTAAAGAAGCAAACGGGGAATGT
GTCACGTACAAGCATGAGACATTAGAGTCTTCGTTGCGAAAAGGATACGCTTTAGGATTTTTAGAAGAGGATGTTTATGT
TTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-275)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5C5AMY2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA Bacillus subtilis subsp. subtilis str. 168

57.925

100

0.579
  pilB Vibrio campbellii strain DS40M4

36.544

100

0.372

Multiple sequence alignment