Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   FE333_RS06750 Genome accession   NZ_CP040412
Coordinates   1451522..1453336 (-) Length   604 a.a.
NCBI ID   WP_112789580.1    Uniprot ID   A0A516GJZ8
Organism   Dolosigranulum pigrum strain KPL3250     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1446522..1458336
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE333_RS06715 (FE333_06685) - 1446716..1447180 (+) 465 WP_208957234.1 GNAT family N-acetyltransferase -
  FE333_RS06720 (FE333_06690) - 1447188..1447625 (+) 438 WP_244359777.1 GNAT family N-acetyltransferase -
  FE333_RS06725 (FE333_06695) - 1447667..1448566 (-) 900 WP_208957236.1 RluA family pseudouridine synthase -
  FE333_RS06730 (FE333_06700) - 1448556..1449368 (-) 813 WP_004636716.1 NAD kinase -
  FE333_RS06735 (FE333_06705) - 1449370..1449999 (-) 630 WP_004636717.1 GTP pyrophosphokinase family protein -
  FE333_RS06740 (FE333_06710) - 1450092..1450679 (+) 588 WP_112768275.1 CYTH domain-containing protein -
  FE333_RS06745 (FE333_06715) - 1450773..1451399 (+) 627 WP_112768274.1 DsbA family protein -
  FE333_RS06750 (FE333_06720) pepF 1451522..1453336 (-) 1815 WP_112789580.1 oligoendopeptidase F Regulator
  FE333_RS06755 (FE333_06725) - 1453482..1454594 (-) 1113 WP_004636721.1 competence protein CoiA family protein -
  FE333_RS06760 (FE333_06730) - 1454697..1455341 (-) 645 WP_004636722.1 adaptor protein MecA -
  FE333_RS06765 (FE333_06735) - 1455444..1455836 (-) 393 WP_004636723.1 ArsC/Spx/MgsR family protein -
  FE333_RS06770 (FE333_06740) - 1455861..1456880 (-) 1020 WP_004636724.1 lipoate--protein ligase -
  FE333_RS06775 - 1457284..1457451 (-) 168 WP_185963592.1 hypothetical protein -

Sequence

Protein


Download         Length: 604 a.a.        Molecular weight: 69486.26 Da        Isoelectric Point: 4.4925

>NTDB_id=364009 FE333_RS06750 WP_112789580.1 1451522..1453336(-) (pepF) [Dolosigranulum pigrum strain KPL3250]
MSDTKQLPKRHEVEEAKTWDLTTIYENDEAWEQDFEAIDDLKDKFVNFQGTLDDGADNFLAAFETLLDLNRKLSKLFVYS
HLKSDQDTENSTYQTLNDRARLKYAEVAEARSWFTPELLSLSQETIDQYFAEAEGLQPYKHEIETILADRDHVLSAEKEA
LLAGASDILSSGSQTFSMLNNADIEFPTVTNEEGEKVQLSHGLYGELIQSTDRSVRQEAFKKMYEVYKGLNNTFASTLQS
DVKKNNYLARVHHYDSARHQALSNNHIPESVHDTLLEVVNENLPLLHRYMALRKELLGLDELHMYDLYPPITGDDSLEYS
FEEAKEATYKGLSVLGDEYKAILDKAFNERWIDVVENKGKRSGAYSSGMYDTNPFILLNWHDSLNHLYTLVHELGHSAHS
YFTRNNQPYVYGDYSIFLAEIASTTNENLLTDYLLKKADSPEEKALILSQYLDGFKGTVFRQTQFAEFEHKIHTAAQEKQ
PLTADFLNKTYAEINDKFYGDVVVNDEEIQYEWSRIPHFYMGYYVYQYSTGFCAATALADKILNEEEGALDAYLGYLKSG
SSDYPIEVMKKAGLDMTNKDYLQRAMDVFEQRLNQLEEVVKEIK

Nucleotide


Download         Length: 1815 bp        

>NTDB_id=364009 FE333_RS06750 WP_112789580.1 1451522..1453336(-) (pepF) [Dolosigranulum pigrum strain KPL3250]
ATGTCAGACACAAAACAATTACCAAAACGTCATGAAGTAGAAGAAGCAAAAACATGGGATTTAACAACCATTTATGAAAA
TGATGAAGCTTGGGAGCAGGATTTTGAAGCGATTGATGACTTGAAAGATAAGTTTGTCAACTTCCAAGGTACTTTGGATG
ACGGGGCCGATAATTTTTTAGCAGCATTTGAGACATTATTGGATCTGAATCGTAAGTTGAGTAAACTCTTTGTATACTCA
CACTTAAAAAGTGATCAAGATACTGAAAATTCAACGTATCAGACTCTTAATGATCGCGCACGCTTGAAATATGCCGAAGT
TGCAGAAGCACGGTCTTGGTTTACACCAGAATTGCTATCACTCTCACAAGAGACGATTGATCAGTACTTTGCTGAAGCAG
AAGGGCTACAACCTTACAAACATGAGATTGAAACTATTTTAGCTGATCGAGATCACGTCTTAAGTGCTGAGAAAGAAGCA
TTATTGGCTGGGGCTAGCGATATTTTATCATCTGGAAGTCAAACCTTCTCGATGTTAAATAATGCCGATATTGAATTTCC
AACAGTGACGAATGAAGAAGGCGAGAAAGTCCAATTATCACACGGATTATACGGAGAGTTGATTCAGAGCACGGATCGAT
CAGTACGCCAGGAAGCCTTCAAGAAAATGTATGAAGTCTACAAGGGCTTAAATAATACATTCGCGTCAACGCTTCAGAGC
GATGTGAAGAAAAATAATTATTTAGCACGTGTGCACCATTACGATTCAGCACGCCATCAAGCGTTATCGAACAATCACAT
TCCAGAGAGCGTGCATGATACCTTGTTAGAAGTGGTGAATGAAAACTTACCGCTCTTACACCGTTATATGGCATTACGTA
AGGAATTACTGGGTCTTGATGAGTTGCATATGTATGATTTATACCCACCGATTACGGGGGATGATAGCTTAGAGTACTCA
TTTGAAGAAGCAAAAGAGGCAACATACAAAGGGTTAAGTGTATTGGGTGATGAGTACAAAGCGATTTTAGATAAAGCATT
CAATGAGCGTTGGATTGATGTGGTTGAGAATAAAGGGAAGCGCAGTGGAGCGTATTCATCAGGAATGTATGATACAAATC
CGTTTATCTTGCTGAACTGGCATGATTCTTTAAATCACTTGTACACCTTAGTACACGAACTGGGACATAGTGCGCACAGT
TACTTCACGCGCAACAATCAGCCGTATGTGTATGGGGACTATTCGATCTTCTTAGCTGAGATCGCCAGCACTACAAACGA
GAATCTATTAACAGATTATCTCTTGAAAAAAGCTGACTCACCTGAAGAGAAAGCACTCATTTTAAGCCAATACTTAGATG
GATTCAAGGGAACAGTCTTCCGTCAGACACAATTTGCTGAATTCGAGCACAAGATTCATACCGCAGCGCAAGAGAAACAA
CCATTGACTGCTGATTTCTTAAATAAAACCTATGCAGAGATTAATGATAAGTTTTATGGCGATGTTGTAGTTAATGATGA
AGAGATCCAATATGAATGGTCGCGTATTCCGCACTTCTATATGGGTTACTATGTATATCAATACTCAACTGGTTTCTGTG
CAGCTACAGCGTTAGCGGACAAAATCTTAAATGAAGAAGAAGGTGCGCTAGATGCGTACTTAGGTTACTTGAAATCCGGT
AGTAGCGATTATCCGATCGAAGTGATGAAAAAAGCTGGTCTCGACATGACGAACAAAGATTACTTGCAACGAGCGATGGA
TGTCTTCGAACAACGCTTGAACCAGCTAGAGGAAGTTGTTAAAGAAATTAAATAA

Domains

Predicted by InterproScan.

Peptidase family M3 (Peptidase_M3)

(207-587)

Oligopeptidase F (Peptidase_M3_N)

(117-186)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A516GJZ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

53.704

98.344

0.528

Multiple sequence alignment