Detailed information NTG0363400

Bioinformatically predicted

Overview

• Name: clpE
• Type: Regulator
• Locus tag: E3S62_RS11030
• Genome accession: NZ_CP047803
• Coordinates: 2243552..2245660 (-)
• Length: 702 a.a.
• NCBI ID: WP_029549251.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain UP_1097
• Function: repress competence development (at the early growth phase) (predicted from homology) Competence regulation

Genomic Context

Location: 2238552..2250660

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S62_RS11015 (E3S62_11015)	-	2241069..2241296 (+)	228	WP_000932073.1	FeoA family protein	-
E3S62_RS11020 (E3S62_11020)	feoB	2241308..2243302 (+)	1995	WP_000432903.1	ferrous iron transport protein B	-
E3S62_RS11025 (E3S62_11025)	-	2243315..2243485 (+)	171	WP_000111116.1	FeoB-associated Cys-rich membrane protein	-
E3S62_RS11030 (E3S62_11030)	clpE	2243552..2245660 (-)	2109	WP_029549251.1	ATP-dependent Clp protease ATP-binding subunit ClpL	Regulator
E3S62_RS11035 (E3S62_11035)	-	2246023..2246544 (+)	522	WP_000262599.1	methylated-DNA--[protein]-cysteine S-methyltransferase	-
E3S62_RS11040 (E3S62_11040)	-	2246715..2247881 (-)	1167	WP_000151984.1	hydroxymethylglutaryl-CoA synthase	-
E3S62_RS11045 (E3S62_11045)	-	2248136..2249416 (+)	1281	WP_001191002.1	hydroxymethylglutaryl-CoA reductase, degradative	-
E3S62_RS11050 (E3S62_11050)	-	2249556..2249987 (-)	432	WP_000875614.1	CHAP domain-containing protein	-
E3S62_RS11055 (E3S62_11055)	-	2250375..2250593 (-)	219	WP_000011687.1	sterile alpha motif-like domain-containing protein	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 78400.83 Da
• Isoelectric Point: 4.6237

>NTDB_id=363400 E3S62_RS11030 WP_029549251.1 2243552..2245660(-) (clpE) [Staphylococcus aureus strain UP_1097]
MNNNFFNSDFDSILRRMMQDMQNSNQTSNKKYYINGKEVSPEELSQFTQQDDNHSAEQSAQAFQQAALRQQGQQSGNGNY
LEQIGRNLTQEARDRLLDPVIGRDKEIQETAEVLSRRTKNNPILVGEAGVGKTAIVEGLAQAIVEGNVPAAIKDKEIISI
DISSLEAGTQYRGAFEENIQKLVEGVKSSQNAVLFFDEIHQIIGSGATGSDSGSKGLSDILKPALSRGEISIIGATTQDE
YRNNIMKDAALTRRFNEVLVNEPSAKDTVEILKGIREKFETHHQVKLPNDVLKACVDLSIQYIPQRLLPDKAIDVLDITA
AHLSAQSPAVDKVETEKRISELENDKRKAVSAEEYKKADDIQNEIKSLQDKLENSNGEHTAVATVHDISDTIQRLTGIPV
SQMDDNDIERLKNISNRLRSKIIGQDQAVEMVSRAIRRNRAGFDDGNRPIGSFLFVGPTGVGKTELAKQLAIDLFGNKEA
LIRLDMSEYSDTTAVSKMIGTTAGYVGYDDNSNTLTEKVRRNPYSVILFDEIEKANPQILTLLLQVMDDGNLTDGQGNVI
NFKNAIVICTSNAGFGNGTDQEYDDIMQEMKKFFRPEFLNRFNGIVEFLHLDKESLQEIINLLLDDVQVTLDKKGITMNV
SQDAKDWLIEEGYDEELGARPLRRIVEQQVRNKITDYYLDHTDVKHVDLDIEDNELVVKGKS

Nucleotide

• Length: 2109 bp

>NTDB_id=363400 E3S62_RS11030 WP_029549251.1 2243552..2245660(-) (clpE) [Staphylococcus aureus strain UP_1097]
ATGAATAACAATTTTTTCAATAGTGATTTCGATTCTATTTTACGAAGAATGATGCAAGACATGCAAAACTCAAATCAGAC
TAGTAACAAGAAATACTATATTAATGGTAAAGAAGTTTCACCGGAAGAATTATCACAATTTACGCAACAAGATGATAATC
ATTCTGCCGAACAAAGTGCGCAAGCTTTTCAACAAGCAGCACTAAGACAACAAGGTCAACAAAGTGGCAATGGCAATTAT
TTAGAACAAATTGGTCGTAACTTAACGCAAGAGGCTCGTGACAGATTATTAGATCCAGTCATCGGTCGTGATAAAGAAAT
CCAAGAAACTGCAGAAGTCTTAAGTAGACGCACTAAAAACAATCCTATCCTAGTCGGAGAAGCTGGAGTTGGTAAAACTG
CGATTGTCGAAGGTTTAGCGCAAGCAATCGTTGAAGGGAATGTACCTGCAGCAATCAAAGATAAAGAAATTATATCTATA
GATATTTCATCTCTTGAAGCTGGAACGCAATATCGTGGCGCCTTTGAAGAAAACATCCAAAAGTTAGTTGAAGGCGTTAA
ATCATCACAAAATGCTGTGCTCTTCTTTGACGAAATTCACCAAATCATCGGTTCCGGCGCAACAGGAAGTGATTCCGGTA
GTAAAGGGTTATCTGATATTTTAAAACCAGCATTAAGTCGTGGTGAAATTTCAATTATAGGTGCAACGACTCAAGATGAA
TATCGCAATAATATCATGAAAGACGCTGCATTAACACGTCGTTTTAACGAGGTACTGGTTAACGAACCAAGCGCAAAAGA
TACGGTTGAAATTTTAAAAGGAATTCGTGAAAAATTTGAAACACACCATCAAGTCAAATTACCTAATGACGTATTAAAGG
CATGTGTAGACTTATCCATTCAATATATTCCACAACGCCTATTACCAGATAAAGCAATCGATGTGTTAGATATTACAGCA
GCACATTTATCTGCGCAAAGTCCAGCTGTCGATAAAGTTGAAACTGAAAAACGAATTTCTGAATTAGAAAATGATAAACG
TAAAGCAGTAAGTGCTGAAGAATATAAAAAAGCTGACGACATTCAAAATGAAATCAAATCATTACAAGATAAATTAGAAA
ACAGTAATGGTGAACATACTGCTGTTGCTACAGTTCATGATATTTCAGATACTATTCAACGATTAACTGGTATTCCAGTT
TCTCAAATGGATGATAACGATATTGAACGTTTAAAAAATATTTCTAATCGTTTAAGAAGTAAAATCATCGGTCAAGACCA
AGCTGTAGAGATGGTTTCACGTGCAATTCGCCGTAATCGTGCTGGATTCGATGACGGCAACCGTCCAATTGGTAGCTTCC
TATTTGTCGGTCCTACTGGTGTTGGTAAAACAGAGCTTGCCAAACAGTTAGCCATTGATTTATTTGGTAATAAAGAGGCA
CTGATTCGACTTGATATGAGTGAATATAGTGATACTACTGCTGTTTCTAAAATGATTGGTACAACTGCTGGTTATGTCGG
TTATGACGATAATTCAAATACATTAACTGAAAAAGTACGACGCAATCCATATTCAGTCATTCTATTTGATGAAATTGAAA
AGGCTAATCCACAAATATTAACATTATTACTTCAAGTGATGGATGATGGTAATTTAACAGATGGTCAAGGTAACGTCATC
AACTTTAAAAACGCAATCGTTATTTGTACGTCAAACGCTGGTTTTGGTAACGGTACAGACCAAGAATACGATGACATTAT
GCAAGAAATGAAAAAATTCTTCCGTCCTGAATTCCTTAACCGCTTCAATGGTATTGTGGAATTCTTACACCTAGATAAAG
AATCACTTCAAGAAATCATTAATTTATTGTTGGATGATGTCCAAGTAACACTAGATAAAAAAGGTATTACGATGAATGTC
TCTCAAGATGCAAAAGATTGGTTAATTGAAGAGGGATATGATGAAGAGTTAGGCGCACGCCCATTAAGACGTATTGTTGA
ACAACAAGTGCGTAACAAAATAACAGATTATTATTTAGATCATACAGACGTTAAACATGTGGATTTAGATATCGAAGACA
ATGAATTAGTCGTCAAAGGTAAATCATGA

Domains

Predicted by InterProScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (611-682)

• ATPase family associated with various cellular activities (AAA) (AAA) (123-257)

• AAA domain (Cdc48 subfamily) (AAA_2) (448-603)

• AAA lid domain (AAA_lid_9) (264-363)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpE	Streptococcus mutans UA159	47.434	91.595	0.434
clpC	Lactococcus lactis subsp. cremoris KW2	44.279	95.869	0.424
clpE	Streptococcus pneumoniae Rx1	47.164	87.892	0.415
clpE	Streptococcus pneumoniae D39	47.164	87.892	0.415
clpE	Streptococcus pneumoniae R6	47.164	87.892	0.415
clpE	Streptococcus pneumoniae TIGR4	47.164	87.892	0.415
clpC	Bacillus subtilis subsp. subtilis str. 168	44.172	92.877	0.41
clpC	Streptococcus thermophilus LMD-9	43.84	89.031	0.39
clpC	Streptococcus thermophilus LMG 18311	43.52	89.031	0.387
clpC	Streptococcus pneumoniae TIGR4	42.492	89.174	0.379
clpC	Streptococcus pneumoniae Rx1	42.492	89.174	0.379
clpC	Streptococcus pneumoniae D39	42.492	89.174	0.379
clpC	Streptococcus mutans UA159	42.927	87.607	0.376
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	41.413	88.746	0.368