Detailed information NTG0036302

Bioinformatically predicted

Overview

• Name: pptA
• Type: Regulator
• Locus tag: SMI_RS01880
• Genome accession: NC_013853
• Coordinates: 356838..357569 (+)
• Length: 243 a.a.
• NCBI ID: WP_000889954.1
• Uniprot ID: F9HLZ7
• Organism: Streptococcus mitis B6
• Function: export ComS (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	354384..356069	356838..357569	flank	769

Gene organization within MGE regions

Location: 354384..357569

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMI_RS01865 (smi_0358)	-	354390..356069 (+)	1680	WP_000276231.1	IS1182-like element ISSmi2 family transposase	-
SMI_RS01870 (smi_0359)	-	356063..356350 (-)	288	WP_000777756.1	hypothetical protein	-
SMI_RS01875 (smi_0360)	-	356360..356770 (-)	411	WP_001278316.1	HIT family protein	-
SMI_RS01880 (smi_0361)	pptA	356838..357569 (+)	732	WP_000889954.1	ABC transporter ATP-binding protein	Regulator

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 27098.58 Da
• Isoelectric Point: 4.6989

>NTDB_id=36302 SMI_RS01880 WP_000889954.1 356838..357569(+) (pptA) [Streptococcus mitis B6]
MLEIKNLTGGYVHVPVLKDVSFTVESGQLVGLIGLNGAGKSTTINEIIGLLTPYSGSININGLTLQEDATSYRKQIGYIP
ETPSLYEELTLREHIETVAMAYGIEQKVAFDRVEPLLKMFRLDQKLDWFPVHFSKGMKQKVMIICAFVVDPSLFIVDEPF
LGLDPLAIADLIQLLEVEKQKGKSILMSTHVLDSAEKMCDAFVILHKGEVRAKGNLLQLREAFDMPEASLNDIYLALTKE
EEL

Nucleotide

• Length: 732 bp

>NTDB_id=36302 SMI_RS01880 WP_000889954.1 356838..357569(+) (pptA) [Streptococcus mitis B6]
ATGTTAGAAATTAAAAACCTGACAGGTGGCTATGTCCATGTCCCTGTCTTGAAAGATGTGTCTTTTACTGTTGAAAGTGG
GCAGCTGGTCGGTTTGATTGGTCTCAATGGTGCTGGGAAATCGACGACTATCAATGAAATTATCGGTCTGTTGACACCTT
ATAGTGGCTCCATCAATATCAATGGCCTGACCCTGCAAGAAGATGCGACTAGCTATCGCAAGCAAATTGGTTACATTCCT
GAGACACCTAGCTTGTATGAGGAATTGACCCTCAGAGAGCATATCGAAACGGTTGCCATGGCTTATGGTATTGAGCAGAA
AGTGGCTTTTGATCGAGTAGAACCTTTGTTAAAAATGTTCCGTCTGGACCAGAAATTGGACTGGTTCCCTGTTCATTTTT
CAAAAGGGATGAAGCAGAAAGTCATGATTATCTGTGCTTTTGTGGTGGATCCGAGTCTTTTCATCGTGGATGAGCCTTTC
CTTGGTCTGGATCCGCTAGCTATTGCAGACTTGATTCAGCTTTTGGAAGTGGAAAAGCAAAAGGGCAAGTCCATTCTCAT
GAGTACCCACGTGCTGGATTCGGCGGAGAAGATGTGTGATGCTTTTGTTATTCTTCACAAAGGGGAAGTGCGTGCCAAAG
GCAATCTCCTACAACTGCGCGAAGCCTTTGATATGCCTGAGGCTAGTTTGAATGATATTTACTTGGCTCTGACCAAAGAG
GAGGAGCTATGA

Domains

Predicted by InterproScan.

• ABC transporter (ABC_tran) (17-160)

3D structure

• AlphaFold DB: F9HLZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pptA	Streptococcus salivarius strain HSISS4	72.614	99.177	0.72
pptA	Streptococcus thermophilus LMD-9	71.784	99.177	0.712