Detailed information NTG0362766

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FD747_RS11535
• Genome accession: NZ_CP040233
• Coordinates: 2314482..2315369 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD1696
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2309482..2320369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD747_RS11505 (FD747_13635)	-	2309491..2309583 (+)	93	WP_031774855.1	hypothetical protein	-
FD747_RS11510 (FD747_13640)	-	2309691..2310188 (-)	498	WP_001065267.1	glutathione peroxidase	-
FD747_RS11515 (FD747_13645)	-	2310198..2310458 (-)	261	WP_014937088.1	hypothetical protein	-
FD747_RS11520 (FD747_13655)	-	2310840..2310953 (-)	114	WP_014937089.1	hypothetical protein	-
FD747_RS11525 (FD747_13660)	-	2311622..2313622 (-)	2001	WP_000776741.1	ABC transporter permease	-
FD747_RS11530 (FD747_13665)	-	2313619..2314374 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
FD747_RS11535 (FD747_13670)	braS	2314482..2315369 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FD747_RS11540 (FD747_13675)	braR	2315380..2316045 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FD747_RS11545 (FD747_13680)	-	2316071..2316271 (-)	201	WP_000604731.1	hypothetical protein	-
FD747_RS11550 (FD747_13685)	-	2316469..2317893 (+)	1425	WP_000953736.1	alkaline phosphatase	-
FD747_RS13995 (FD747_13690)	-	2317953..2318054 (-)	102	WP_000731972.1	SE2200 family small protein	-
FD747_RS11560 (FD747_13695)	-	2318176..2318631 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FD747_RS11565 (FD747_13700)	-	2318875..2319636 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=362766 FD747_RS11535 WP_000143420.1 2314482..2315369(-) (braS) [Staphylococcus aureus strain GD1696]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=362766 FD747_RS11535 WP_000143420.1 2314482..2315369(-) (braS) [Staphylococcus aureus strain GD1696]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993