Detailed information NTG0362761

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: FD747_RS08015
• Genome accession: NZ_CP040233
• Coordinates: 1613219..1614262 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain GD1696
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1608219..1619262

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD747_RS07985 (FD747_10020)	-	1608640..1609896 (-)	1257	WP_001793428.1	aminopeptidase	-
FD747_RS07990 (FD747_10025)	-	1609899..1610099 (-)	201	WP_000180460.1	DUF1128 family protein	-
FD747_RS07995 (FD747_10030)	-	1610246..1610710 (+)	465	WP_138765684.1	low molecular weight protein-tyrosine-phosphatase	-
FD747_RS08000 (FD747_10035)	-	1610717..1610992 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
FD747_RS08005 (FD747_10040)	-	1611270..1612487 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
FD747_RS08010 (FD747_10045)	vraR	1612600..1613229 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
FD747_RS08015 (FD747_10050)	vraS	1613219..1614262 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
FD747_RS08020 (FD747_10055)	liaF	1614259..1614960 (-)	702	WP_031886362.1	cell wall-active antibiotics response protein LiaF	-
FD747_RS08025 (FD747_10060)	-	1614975..1615361 (-)	387	WP_001110182.1	hypothetical protein	-
FD747_RS08030 (FD747_10065)	map	1615578..1616336 (-)	759	WP_000636145.1	type I methionyl aminopeptidase	-
FD747_RS08035 (FD747_10070)	-	1616810..1617796 (+)	987	WP_000999712.1	aromatic acid exporter family protein	-
FD747_RS08040 (FD747_10075)	-	1617985..1618398 (-)	414	WP_025174370.1	hypothetical protein	-
FD747_RS08045 (FD747_10080)	-	1618427..1618537 (-)	111	WP_014937049.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=362761 FD747_RS08015 WP_001017131.1 1613219..1614262(-) (vraS) [Staphylococcus aureus strain GD1696]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=362761 FD747_RS08015 WP_001017131.1 1613219..1614262(-) (vraS) [Staphylococcus aureus strain GD1696]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTTCTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAATTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAATTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGCTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1