Detailed information NTG0362725

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FD746_RS14095
• Genome accession: NZ_CP040232
• Coordinates: 2771366..2772253 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD1706
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2766366..2777253

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD746_RS14060 (FD746_14090)	-	2766375..2766467 (+)	93	WP_031774855.1	hypothetical protein	-
FD746_RS14065 (FD746_14095)	-	2766575..2767072 (-)	498	WP_001065267.1	glutathione peroxidase	-
FD746_RS14070 (FD746_14100)	-	2767082..2767342 (-)	261	WP_014937088.1	hypothetical protein	-
FD746_RS14080 (FD746_14110)	-	2767724..2767837 (-)	114	WP_014937089.1	hypothetical protein	-
FD746_RS14085 (FD746_14115)	-	2768506..2770506 (-)	2001	WP_149888557.1	ABC transporter permease	-
FD746_RS14090 (FD746_14120)	-	2770503..2771258 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
FD746_RS14095 (FD746_14125)	braS	2771366..2772253 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FD746_RS14100 (FD746_14130)	braR	2772264..2772929 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FD746_RS14105 (FD746_14135)	-	2772955..2773155 (-)	201	WP_000604731.1	hypothetical protein	-
FD746_RS14110 (FD746_14140)	-	2773353..2774777 (+)	1425	WP_000953736.1	alkaline phosphatase	-
FD746_RS14905 (FD746_14145)	-	2774837..2774938 (-)	102	WP_000731972.1	SE2200 family small protein	-
FD746_RS14120 (FD746_14150)	-	2775060..2775515 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FD746_RS14125 (FD746_14155)	-	2775759..2776520 (-)	762	WP_000323448.1	alpha/beta hydrolase	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=362725 FD746_RS14095 WP_000143420.1 2771366..2772253(-) (braS) [Staphylococcus aureus strain GD1706]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=362725 FD746_RS14095 WP_000143420.1 2771366..2772253(-) (braS) [Staphylococcus aureus strain GD1706]
ATGACCTTTCTTAAAAGTATTACCCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993