Detailed information NTG0362603

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FD491_RS10145
• Genome accession: NZ_CP040230
• Coordinates: 2100543..2101430 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD1108
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2095543..2106430

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD491_RS10115 (FD491_13630)	-	2096276..2097037 (+)	762	WP_000323448.1	alpha/beta hydrolase family protein	-
FD491_RS10120 (FD491_13625)	-	2097281..2097736 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FD491_RS13845 (FD491_13620)	-	2097858..2097959 (+)	102	WP_000731972.1	SE2200 family small protein	-
FD491_RS10130 (FD491_13615)	-	2098019..2099443 (-)	1425	WP_000953736.1	alkaline phosphatase	-
FD491_RS10135 (FD491_13610)	-	2099641..2099841 (+)	201	WP_000604731.1	hypothetical protein	-
FD491_RS10140 (FD491_13605)	braR	2099867..2100532 (+)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FD491_RS10145 (FD491_13600)	braS	2100543..2101430 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FD491_RS10150 (FD491_13595)	-	2101538..2102293 (+)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
FD491_RS10155 (FD491_13590)	-	2102290..2104290 (+)	2001	WP_000776741.1	ABC transporter permease	-
FD491_RS10160 (FD491_13585)	-	2104959..2105072 (+)	114	WP_014937089.1	hypothetical protein	-
FD491_RS10165 (FD491_13575)	-	2105454..2105714 (+)	261	WP_014937088.1	hypothetical protein	-
FD491_RS10170 (FD491_13570)	-	2105724..2106221 (+)	498	WP_001065267.1	glutathione peroxidase	-
FD491_RS10175 (FD491_13565)	-	2106329..2106421 (-)	93	WP_031774855.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=362603 FD491_RS10145 WP_000143420.1 2100543..2101430(+) (braS) [Staphylococcus aureus strain GD1108]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=362603 FD491_RS10145 WP_000143420.1 2100543..2101430(+) (braS) [Staphylococcus aureus strain GD1108]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993