Detailed information NTG0362565

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: FD482_RS13155
• Genome accession: NZ_CP040229
• Coordinates: 2654297..2655184 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain GD487
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2649297..2660184

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FD482_RS13125 (FD482_13475)	-	2649306..2649398 (+)	93	WP_031774855.1	hypothetical protein	-
FD482_RS13130 (FD482_13480)	-	2649506..2650003 (-)	498	WP_001065267.1	glutathione peroxidase	-
FD482_RS13135 (FD482_13485)	-	2650013..2650273 (-)	261	WP_014937088.1	hypothetical protein	-
FD482_RS13140 (FD482_13495)	-	2650655..2650768 (-)	114	WP_014937089.1	hypothetical protein	-
FD482_RS13145 (FD482_13500)	-	2651437..2653437 (-)	2001	WP_000776741.1	ABC transporter permease	-
FD482_RS13150 (FD482_13505)	-	2653434..2654189 (-)	756	WP_000923768.1	ABC transporter ATP-binding protein	-
FD482_RS13155 (FD482_13510)	braS	2654297..2655184 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
FD482_RS13160 (FD482_13515)	braR	2655195..2655860 (-)	666	WP_000697873.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
FD482_RS13165 (FD482_13520)	-	2655886..2656086 (-)	201	WP_000604731.1	hypothetical protein	-
FD482_RS13170 (FD482_13525)	-	2656284..2657708 (+)	1425	WP_000953736.1	alkaline phosphatase	-
FD482_RS13830 (FD482_13530)	-	2657768..2657869 (-)	102	WP_000731972.1	SE2200 family small protein	-
FD482_RS13180 (FD482_13535)	-	2657991..2658446 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
FD482_RS13185 (FD482_13540)	-	2658690..2659451 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=362565 FD482_RS13155 WP_000143420.1 2654297..2655184(-) (braS) [Staphylococcus aureus strain GD487]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=362565 FD482_RS13155 WP_000143420.1 2654297..2655184(-) (braS) [Staphylococcus aureus strain GD487]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993