Detailed information NTG0362376

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: E6P00_RS28025
• Genome accession: NZ_CP040127
• Coordinates: 5365237..5366574 (+)
• Length: 445 a.a.
• NCBI ID: WP_003094694.1
• Uniprot ID: A0A0H2ZG94
• Organism: Pseudomonas aeruginosa strain PA298
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 5360237..5371574

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E6P00_RS28000 (E6P00_28000)	pgeF	5360380..5361108 (-)	729	WP_003119426.1	peptidoglycan editing factor PgeF	-
E6P00_RS28005 (E6P00_28005)	rluD	5361105..5362067 (-)	963	WP_003094686.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
E6P00_RS28010 (E6P00_28010)	-	5362213..5363238 (+)	1026	WP_003102590.1	outer membrane protein assembly factor BamD	-
E6P00_RS28015 (E6P00_28015)	-	5363395..5363640 (+)	246	WP_003102591.1	PP0621 family protein	-
E6P00_RS28020 (E6P00_28020)	pilS	5363630..5365222 (+)	1593	WP_003119425.1	two-component system sensor histidine kinase PilS	Regulator
E6P00_RS28025 (E6P00_28025)	pilR	5365237..5366574 (+)	1338	WP_003094694.1	two-component system response regulator PilR	Regulator
E6P00_RS28030 (E6P00_28030)	thiO	5366620..5367714 (-)	1095	WP_003119424.1	glycine oxidase ThiO	-
E6P00_RS28035 (E6P00_28035)	-	5367849..5368358 (+)	510	WP_003102595.1	Tfp pilus assembly protein FimT/FimU	-
E6P00_RS28040 (E6P00_28040)	-	5368464..5368970 (+)	507	WP_003102598.1	Tfp pilus assembly protein FimT/FimU	-
E6P00_RS28045 (E6P00_28045)	pilV	5368961..5369518 (+)	558	WP_003119423.1	type 4a pilus minor pilin PilV	Machinery gene
E6P00_RS28050 (E6P00_28050)	pilW	5369515..5370339 (+)	825	WP_003119422.1	type 4a pilus minor pilin PilW	-
E6P00_RS28055 (E6P00_28055)	pilX	5370336..5370923 (+)	588	WP_015648054.1	type 4a pilus minor pilin PilX	-

Sequence

Protein

• Length: 445 a.a.
• Molecular weight: 49737.06 Da
• Isoelectric Point: 5.8654

>NTDB_id=362376 E6P00_RS28025 WP_003094694.1 5365237..5366574(+) (pilR) [Pseudomonas aeruginosa strain PA298]
MSRQKALIVDDEPDIRELLEITLGRMKLDTRSARNVKEARELLAREPFDLCLTDMRLPDGSGLDLVQYIQQRHPQTPVAM
ITAYGSLDTAIQALKAGAFDFLTKPVDLGRLRELVATALRLRNPEAEEAPVDNRLLGESPPMRALRNQIGKLARSQAPVY
ISGESGSGKELVARLIHEQGPRIERPFVPVNCGAIPSELMESEFFGHKKGSFTGAIEDKQGLFQAASGGTLFLDEVADLP
MAMQVKLLRAIQEKAVRAVGGQQEVAVDVRILCATHKDLAAEVGAGRFRQDLYYRLNVIELRVPPLRERREDIPLLAERI
LKRLAGDTGLPAARLTGDAQEKLKNYRFPGNVRELENMLERAYTLCEDDQIQPHDLRLADAPGASQEGAASLSEIDNLED
YLEDIERKLIMQALEETRWNRTAAAQRLGLTFRSMRYRLKKLGID

Nucleotide

• Length: 1338 bp

>NTDB_id=362376 E6P00_RS28025 WP_003094694.1 5365237..5366574(+) (pilR) [Pseudomonas aeruginosa strain PA298]
ATGAGCCGACAAAAAGCCCTGATCGTCGACGATGAACCGGATATCCGCGAACTGCTGGAAATCACTCTCGGCCGCATGAA
GCTGGACACCCGCAGCGCCCGCAACGTCAAGGAAGCCCGCGAGTTGCTGGCCCGCGAGCCGTTCGACCTGTGCCTCACCG
ACATGCGCCTGCCGGACGGCAGCGGCCTCGATCTGGTCCAGTACATCCAGCAGCGCCATCCACAGACCCCGGTGGCCATG
ATCACCGCGTACGGCAGCCTGGACACCGCGATCCAGGCGCTCAAGGCCGGTGCCTTCGACTTCCTCACCAAACCGGTCGA
CCTCGGTCGCTTGCGGGAGCTGGTGGCAACCGCCCTGCGCTTGCGCAACCCGGAAGCCGAGGAAGCGCCGGTGGACAACC
GCCTGCTCGGCGAGTCGCCGCCGATGCGCGCCCTGCGCAACCAGATCGGCAAGCTGGCGCGCAGCCAGGCGCCGGTCTAC
ATCAGTGGCGAGTCCGGTAGCGGCAAGGAGCTGGTGGCGCGCCTGATCCACGAGCAGGGGCCACGTATCGAGCGGCCGTT
CGTGCCGGTGAACTGCGGCGCGATTCCCTCCGAACTGATGGAAAGCGAGTTCTTCGGCCACAAGAAAGGCAGCTTCACTG
GCGCTATCGAAGACAAGCAGGGCCTGTTCCAGGCCGCCAGCGGCGGCACCCTGTTCCTCGACGAAGTCGCCGACCTGCCG
ATGGCCATGCAGGTCAAACTGCTCCGGGCGATCCAGGAAAAGGCCGTGCGCGCGGTCGGCGGCCAGCAGGAGGTCGCCGT
CGACGTGCGCATCCTCTGCGCCACCCACAAGGACCTCGCCGCCGAAGTCGGCGCCGGGCGCTTCCGCCAGGACCTCTACT
ACCGCCTCAACGTCATCGAGCTGCGCGTACCGCCGCTGCGCGAACGCCGCGAGGACATCCCGCTGCTCGCCGAACGCATC
CTCAAGCGCCTGGCCGGCGACACCGGCCTGCCGGCCGCCAGGCTGACCGGCGACGCACAGGAGAAGCTGAAGAACTACCG
CTTCCCGGGCAACGTCCGCGAGCTGGAAAACATGCTGGAGCGCGCCTACACCCTGTGCGAAGACGACCAGATCCAGCCTC
ACGACCTGCGCCTGGCCGATGCGCCGGGTGCCAGCCAGGAAGGCGCCGCGAGCCTGAGCGAAATAGACAACCTCGAGGAC
TACCTGGAAGACATCGAGCGCAAGCTGATCATGCAGGCGCTCGAGGAGACCCGCTGGAACCGCACCGCCGCGGCCCAGCG
CCTGGGCCTGACGTTCCGCTCGATGCGCTACCGCCTGAAAAAGCTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (7-115)

• Sigma-54 interaction domain (Sigma54_activat) (135-301)

• Bacterial regulatory protein, Fis family (HTH_8) (402-442)

3D structure

• AlphaFold DB: A0A0H2ZG94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	100	100	1
pilR	Acinetobacter baumannii strain A118	51.198	100	0.528
luxO	Vibrio cholerae strain A1552	38.17	100	0.384