Detailed information NTG0361971

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: E3S97_RS09075
• Genome accession: NZ_CP047787
• Coordinates: 1876251..1877294 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: Q99SZ7
• Organism: Staphylococcus aureus strain UP_1108
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1871251..1882294

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3S97_RS09045 (E3S97_09045)	-	1871672..1872919 (-)	1248	WP_000656302.1	aminopeptidase	-
E3S97_RS09050 (E3S97_09050)	-	1872931..1873131 (-)	201	WP_000180459.1	DUF1128 family protein	-
E3S97_RS09055 (E3S97_09055)	-	1873278..1873742 (+)	465	WP_000228668.1	low molecular weight protein-tyrosine-phosphatase	-
E3S97_RS09060 (E3S97_09060)	-	1873749..1874024 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
E3S97_RS09065 (E3S97_09065)	-	1874302..1875519 (+)	1218	WP_000037083.1	YihY/virulence factor BrkB family protein	-
E3S97_RS09070 (E3S97_09070)	vraR	1875632..1876261 (-)	630	WP_000153535.1	two-component system response regulator VraR	Regulator
E3S97_RS09075 (E3S97_09075)	vraS	1876251..1877294 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
E3S97_RS09080 (E3S97_09080)	liaF	1877291..1877992 (-)	702	WP_000149064.1	cell wall-active antibiotics response protein LiaF	-
E3S97_RS09085 (E3S97_09085)	-	1878007..1878393 (-)	387	WP_001110184.1	hypothetical protein	-
E3S97_RS09090 (E3S97_09090)	map	1878610..1879368 (-)	759	WP_000636137.1	type I methionyl aminopeptidase	-
E3S97_RS09095 (E3S97_09095)	-	1879899..1880885 (+)	987	WP_000999713.1	FUSC family protein	-
E3S97_RS09100 (E3S97_09100)	-	1881063..1881476 (-)	414	WP_001622129.1	hypothetical protein	-
E3S97_RS09105 (E3S97_09105)	-	1881505..1881614 (-)	110	Protein_1758	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=361971 E3S97_RS09075 WP_001017131.1 1876251..1877294(-) (vraS) [Staphylococcus aureus strain UP_1108]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=361971 E3S97_RS09075 WP_001017131.1 1876251..1877294(-) (vraS) [Staphylococcus aureus strain UP_1108]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATATTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATA
CAAGATTTTAAAGTACCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTCGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCAGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterProScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: Q99SZ7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1