Detailed information NTG0036196

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: GALLO_RS06545
• Genome accession: NC_013798
• Coordinates: 1319051..1321159 (+)
• Length: 702 a.a.
• NCBI ID: WP_012962041.1
• Uniprot ID: A0A060RHT7
• Organism: Streptococcus gallolyticus UCN34
• Function: degradation of ComX (predicted from homology) Competence regulation

Genomic Context

Location: 1314051..1326159

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GALLO_RS06520 (GALLO_1244)	-	1316012..1316608 (+)	597	WP_009854348.1	TetR/AcrR family transcriptional regulator	-
GALLO_RS06525 (GALLO_1245)	-	1316688..1317152 (-)	465	WP_012962039.1	hypothetical protein	-
GALLO_RS06530 (GALLO_1246)	-	1317270..1317470 (+)	201	WP_012962040.1	helix-turn-helix domain-containing protein	-
GALLO_RS06535 (GALLO_1247)	rplL	1317571..1317939 (-)	369	WP_009854351.1	50S ribosomal protein L7/L12	-
GALLO_RS06540 (GALLO_1248)	rplJ	1318008..1318511 (-)	504	WP_009854352.1	50S ribosomal protein L10	-
GALLO_RS06545 (GALLO_1249)	clpC	1319051..1321159 (+)	2109	WP_012962041.1	AAA family ATPase	Regulator
GALLO_RS06550 (GALLO_1250)	-	1321266..1321913 (+)	648	WP_012962042.1	endonuclease III domain-containing protein	-
GALLO_RS06555 (GALLO_1251)	-	1322022..1322690 (+)	669	WP_039694591.1	YoaK family protein	-
GALLO_RS06560 (GALLO_1252)	mmuM	1322730..1323677 (-)	948	WP_012962044.1	homocysteine S-methyltransferase	-
GALLO_RS06565 (GALLO_1253)	-	1323690..1325066 (-)	1377	WP_012962045.1	amino acid permease	-
GALLO_RS06570 (GALLO_1254)	yihA	1325365..1325958 (-)	594	WP_012962046.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-

Sequence

Protein

• Length: 702 a.a.
• Molecular weight: 77210.96 Da
• Isoelectric Point: 4.7283

>NTDB_id=36196 GALLO_RS06545 WP_012962041.1 1319051..1321159(+) (clpC) [Streptococcus gallolyticus UCN34]
MANNNFYGRDPFGNMDDIFNELMGNMGGYNSENRRYLINGREVTPEEFAQYRQTGKLPGNAEYQEGAPTSAPKEDGILAK
LGTNLTERARANELDPVIGRNKEIQETAEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDIS
GLEAGTQYRGAFEENIQNLVKEVKDAGNIILFFDEIHQILGAGSTGGDSGSKGLADILKPALSRGELTVIGATTQDEYRN
TILKNAALARRFNEVKVNAPSAQDSFNILMGIRDLYEKHHNVILPDNVLKAAVDFSIQYIPQRSLPDKAIDLIDMTAAHL
AAQHPATDVKSLEKEIADQKEKQENAVAKEDYEAALNAKVRIEELQKQIDNHTEGQKVTATVNDVAESVERLTGVPVSNM
GASDIERLKELASRLKGKVIGQDEAVEAVSRAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGSKDAIIR
LDMSEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTINFK
NTVIIATSNAGFGNEALTGQDDKDKKIMDRIAPYFRPEFLNRFNGIIEFSHLTKEDLNDIVDLMLDEVSKTIAKKGIDLV
VSDAAKQHLIEEGYDEAMGVRPLRRVIEQEIRDKITDFYLDHTDVKHLKADMVDGELVISEK

Nucleotide

• Length: 2109 bp

>NTDB_id=36196 GALLO_RS06545 WP_012962041.1 1319051..1321159(+) (clpC) [Streptococcus gallolyticus UCN34]
ATGGCAAATAATAATTTTTACGGAAGAGATCCTTTTGGAAATATGGATGACATTTTTAATGAACTTATGGGTAACATGGG
CGGGTACAATTCAGAAAACAGACGCTATTTGATTAATGGGCGCGAAGTTACTCCTGAAGAATTTGCACAATATCGCCAAA
CAGGTAAGCTCCCTGGAAACGCGGAATACCAAGAAGGGGCGCCTACTTCTGCTCCTAAAGAAGATGGTATCTTGGCAAAA
TTAGGAACAAACTTGACCGAACGCGCACGCGCTAACGAACTCGACCCTGTTATTGGACGTAACAAAGAAATCCAAGAAAC
TGCTGAAATCTTGTCACGTCGTACCAAAAACAACCCTGTCCTTGTGGGGGACGCAGGTGTTGGTAAAACAGCCGTTGTCG
AAGGCTTAGCGCAAGCTATTGTCAATGGTGATGTGCCAGCAGCTATCAAAAATAAAGAAATCATTTCTATTGATATTTCT
GGTCTTGAAGCTGGCACACAATATCGTGGTGCTTTTGAAGAAAATATCCAAAACCTTGTCAAAGAAGTTAAAGACGCTGG
TAATATCATTCTCTTCTTTGATGAAATCCACCAAATTTTAGGCGCAGGGTCAACTGGTGGTGACTCTGGTTCGAAAGGCT
TAGCTGACATTCTCAAACCTGCACTTTCTCGTGGCGAATTGACCGTTATCGGTGCAACAACTCAAGACGAATATCGTAAT
ACTATTTTGAAGAATGCTGCGCTCGCTCGCCGTTTCAACGAAGTCAAAGTAAATGCTCCTTCTGCTCAAGATAGCTTTAA
TATTTTAATGGGAATTCGTGATTTATATGAAAAACACCACAACGTTATTCTCCCTGATAATGTGTTAAAAGCCGCTGTTG
ATTTTTCAATTCAATATATCCCACAACGTAGTTTACCAGATAAAGCTATTGACTTGATTGATATGACTGCTGCTCATTTG
GCTGCTCAACACCCTGCAACTGATGTCAAATCTCTTGAAAAGGAAATTGCAGACCAAAAAGAAAAACAAGAAAATGCTGT
GGCTAAAGAAGATTACGAAGCAGCTCTCAATGCCAAGGTTCGTATCGAAGAATTGCAAAAACAAATTGACAACCATACGG
AAGGGCAAAAAGTTACAGCTACCGTTAATGATGTGGCAGAATCTGTCGAACGATTAACTGGTGTTCCCGTGTCAAATATG
GGAGCAAGTGATATTGAACGCTTGAAAGAATTAGCTAGCCGTTTGAAAGGTAAAGTCATCGGACAAGATGAGGCTGTTGA
AGCCGTCTCACGTGCCATTCGTCGTAACCGTGCTGGTTTTGACGAAGGTAATCGACCAATTGGTAGTTTCCTCTTTGTCG
GTCCTACTGGCGTTGGTAAGACAGAGCTTGCTAAACAATTAGCCCTTGATATGTTCGGCTCAAAAGATGCTATTATCCGC
CTTGACATGTCTGAATACTCTGATCGCACAGCCGTTTCTAAATTAATCGGTACAACTGCTGGCTATGTTGGCTACGACGA
CAATAGCAACACGCTTACTGAACGTGTTCGTCGTAACCCATACTCAATTGTTCTTCTTGATGAAATTGAAAAAGCTGACC
CTCAAGTCATCACACTTCTTCTCCAAGTTTTGGATGATGGTCGTTTGACAGACGGTCAAGGTAATACGATTAACTTTAAG
AATACCGTCATCATTGCTACCTCTAATGCTGGATTCGGCAACGAAGCTTTGACTGGTCAAGATGATAAAGATAAGAAAAT
TATGGATCGTATCGCTCCATACTTCCGCCCAGAATTTCTTAACCGTTTCAACGGTATTATCGAATTCTCTCACTTGACTA
AAGAAGATTTGAACGACATTGTTGACTTAATGCTTGACGAAGTTAGCAAGACCATTGCCAAGAAAGGCATTGATTTGGTG
GTTAGTGATGCTGCTAAACAACACCTTATCGAAGAAGGTTATGATGAAGCCATGGGTGTTCGACCACTCCGCCGTGTCAT
TGAACAAGAAATCCGCGATAAAATCACTGATTTCTACCTCGATCACACAGATGTTAAACACCTTAAAGCTGACATGGTTG
ACGGAGAACTAGTCATCAGCGAAAAATAA

Domains

Predicted by InterproScan.

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (612-683)

• AAA domain (Cdc48 subfamily) (AAA_2) (445-604)

• AAA lid domain (AAA_lid_9) (262-355)

• ATPase family associated with various cellular activities (AAA) (AAA) (120-252)

3D structure

• AlphaFold DB: A0A060RHT7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Lactococcus lactis subsp. cremoris KW2	48.927	99.573	0.487
clpE	Streptococcus mutans UA159	49.451	90.741	0.449
clpE	Streptococcus pneumoniae Rx1	48.594	91.168	0.443
clpE	Streptococcus pneumoniae D39	48.594	91.168	0.443
clpE	Streptococcus pneumoniae R6	48.594	91.168	0.443
clpE	Streptococcus pneumoniae TIGR4	48.661	90.456	0.44
clpC	Bacillus subtilis subsp. subtilis str. 168	45.127	95.014	0.429
clpC	Streptococcus pneumoniae Rx1	43.76	90.171	0.395
clpC	Streptococcus pneumoniae D39	43.76	90.171	0.395
clpC	Streptococcus pneumoniae TIGR4	43.81	89.744	0.393
clpC	Streptococcus thermophilus LMD-9	43.387	88.319	0.383
clpC	Lactococcus lactis subsp. lactis strain DGCC12653	43.457	88.177	0.383
clpC	Streptococcus thermophilus LMG 18311	43.204	88.034	0.38
clpC	Streptococcus mutans UA159	42.697	88.746	0.379