Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GALLO_RS03370 Genome accession   NC_013798
Coordinates   635561..637849 (-) Length   762 a.a.
NCBI ID   WP_012961625.1    Uniprot ID   A0AA36JWR5
Organism   Streptococcus gallolyticus UCN34     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 630561..642849
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GALLO_RS03355 (GALLO_0609) ileS 631562..634360 (+) 2799 WP_012961622.1 isoleucine--tRNA ligase -
  GALLO_RS03360 (GALLO_0610) - 634461..634763 (-) 303 WP_012961623.1 DUF1827 family protein -
  GALLO_RS03365 (GALLO_0611) - 634835..635281 (-) 447 WP_012961624.1 NUDIX hydrolase -
  GALLO_RS03370 (GALLO_0612) clpE 635561..637849 (-) 2289 WP_012961625.1 ATP-dependent Clp protease ATP-binding subunit Regulator
  GALLO_RS03375 (GALLO_0613) - 637990..638517 (-) 528 WP_012961626.1 DUF3278 domain-containing protein -
  GALLO_RS03380 (GALLO_0614) - 638545..638742 (-) 198 WP_012961627.1 helix-turn-helix transcriptional regulator -
  GALLO_RS03385 (GALLO_0615) argF 638938..639918 (+) 981 WP_012961628.1 ornithine carbamoyltransferase -
  GALLO_RS03390 (GALLO_0616) - 640053..640283 (+) 231 WP_003063726.1 DUF1797 family protein -
  GALLO_RS03395 (GALLO_0617) - 640537..641223 (+) 687 WP_009853706.1 amino acid ABC transporter permease -
  GALLO_RS03400 (GALLO_0618) - 641223..641957 (+) 735 WP_012961629.1 amino acid ABC transporter ATP-binding protein -
  GALLO_RS03405 (GALLO_0619) - 642324..642800 (+) 477 WP_012961630.1 FeoA family protein -

Sequence

Protein


Download         Length: 762 a.a.        Molecular weight: 84838.77 Da        Isoelectric Point: 4.7854

>NTDB_id=36187 GALLO_RS03370 WP_012961625.1 635561..637849(-) (clpE) [Streptococcus gallolyticus UCN34]
MLCQNCHLNESTIHLYTNVNGQQKQIDLCQNCYQIMKTDPNNTILGGLGDAQASSTQNQSTGMNPFDDFFSNLNNFHAFG
GQDFQNTPPTQSGGGNNGGNNNNYRPNGAANQQQQQKGLLEEFGINVTDIARRGDIDPVIGRDAEIIRVIEILNRRTKNN
PVLIGEPGVGKTAVVEGLAQKIVDGNVPQKLQNKQVIRLDVVSLVQGTGIRGQFEERMQKLMEEIRERKDVILFIDEIHE
IVGAGSAGDGNMDAGNILKPALARGELQLVGATTLNEYRIIEKDAALERRMQPVKVDEPSVEETITILRGIQKKYEDYHH
VKYSDDAIEAAANLSNRYIQDRFLPDKAIDLLDEAGSKMNLTLNFVDPQEIDKRLVEAENLKTQATREEDYERAAYFRDQ
IAKYKEMQQQTINEDDIPVITEKTIEAIVEEKTNIPVGDLKEKEQSQLINLADDLKTHVIGQDDAVDKIAKAIRRNRVGL
GTPNRPIGSFLFVGPTGVGKTELSKQLAIELFGSADSMIRFDMSEYMEKHAVAKLVGAPPGYVGYEEAGQLTEKVRRNPY
SLILLDEVEKAHPDVMHMFLQVLDDGRLTDGQGRTVSFKDTIIIMTSNAGTGKTEASVGFGAAREGRTNSVLGELSNYFS
PEFMNRFDGIIEFKALSKDILLQIVNLMLDDVNKRLATNDIHLEVTDKVKEKLVDLGYDPKMGARPLRRTIQDHIEDAIT
DFYLENPSEKDLKAVMTSNGKIIIKSAKKVEKEETTVSAESE

Nucleotide


Download         Length: 2289 bp        

>NTDB_id=36187 GALLO_RS03370 WP_012961625.1 635561..637849(-) (clpE) [Streptococcus gallolyticus UCN34]
ATGCTCTGTCAAAATTGTCATTTAAACGAATCAACAATTCATCTTTATACAAATGTCAATGGTCAGCAAAAGCAAATTGA
TTTGTGCCAAAACTGCTATCAAATCATGAAAACTGACCCTAACAATACTATTTTAGGTGGTTTAGGCGATGCACAAGCTT
CTTCCACACAAAATCAATCTACTGGTATGAATCCTTTTGATGATTTCTTCAGTAATTTGAATAATTTCCACGCATTCGGT
GGACAAGATTTCCAAAATACGCCTCCAACACAATCAGGTGGTGGAAATAACGGCGGCAATAATAACAATTATCGTCCAAA
CGGCGCAGCTAACCAACAGCAACAACAAAAAGGTTTGCTAGAAGAATTTGGTATCAACGTTACTGATATTGCTCGTCGCG
GTGACATCGACCCTGTCATTGGACGTGATGCCGAAATCATTCGTGTGATTGAAATTCTTAACCGTCGTACCAAAAATAAT
CCTGTTCTTATTGGTGAACCAGGGGTTGGTAAAACAGCCGTTGTTGAAGGATTAGCTCAAAAAATCGTAGATGGTAACGT
TCCACAAAAACTTCAAAATAAACAAGTTATTCGTCTTGATGTCGTTAGCCTTGTACAAGGAACAGGTATTCGTGGTCAAT
TTGAAGAACGTATGCAAAAACTCATGGAAGAAATCCGTGAACGCAAGGACGTTATTCTCTTCATTGACGAAATTCACGAA
ATTGTCGGTGCTGGTTCTGCAGGCGACGGCAACATGGACGCTGGTAATATTTTAAAACCAGCACTTGCTCGTGGTGAACT
TCAATTAGTTGGTGCTACAACACTCAATGAATACCGCATTATTGAAAAAGATGCGGCGCTTGAACGCCGTATGCAACCTG
TCAAAGTTGATGAACCAAGCGTGGAAGAAACGATTACGATTCTTCGTGGTATTCAAAAGAAATACGAAGATTATCATCAT
GTCAAATACAGCGATGATGCAATTGAGGCTGCCGCAAATCTTTCTAACCGTTACATTCAAGACCGCTTCCTCCCAGATAA
AGCCATTGATTTGCTAGACGAAGCTGGTTCTAAGATGAATTTAACCCTTAACTTTGTTGACCCACAAGAAATCGACAAGC
GTTTAGTGGAAGCTGAAAACCTAAAAACACAAGCTACTCGCGAAGAAGATTATGAACGCGCAGCTTATTTCCGTGACCAA
ATCGCTAAATACAAGGAAATGCAACAACAAACAATCAACGAAGACGATATTCCAGTCATTACTGAAAAGACTATCGAAGC
TATCGTTGAAGAAAAAACTAACATCCCTGTTGGTGATTTGAAAGAAAAGGAACAATCACAATTAATCAATCTCGCTGATG
ATTTGAAAACACACGTCATTGGTCAAGATGATGCCGTTGACAAAATTGCCAAAGCCATTCGTCGTAACCGTGTCGGTCTC
GGTACACCAAATCGTCCAATCGGTTCATTCCTCTTTGTTGGACCAACTGGTGTTGGTAAAACAGAACTTTCTAAACAATT
AGCGATTGAACTTTTCGGCTCAGCTGACAGCATGATTCGTTTCGATATGTCTGAATACATGGAAAAACATGCGGTTGCTA
AACTTGTCGGAGCACCTCCAGGATACGTTGGTTACGAAGAAGCTGGTCAATTGACAGAAAAAGTTCGCCGTAATCCGTAC
TCACTCATCCTTCTTGACGAAGTTGAAAAAGCGCATCCTGATGTTATGCATATGTTCTTGCAAGTTCTTGATGACGGTCG
TTTGACTGACGGTCAAGGTCGTACAGTAAGCTTCAAAGATACTATTATTATCATGACTTCTAATGCTGGTACTGGTAAAA
CAGAAGCTTCAGTTGGTTTCGGTGCTGCTCGTGAAGGACGTACAAATTCTGTCCTTGGTGAACTTAGCAACTACTTCAGC
CCTGAATTCATGAACCGTTTCGATGGTATTATCGAATTTAAGGCTCTTAGCAAAGACATTCTTCTCCAAATTGTTAACCT
TATGCTTGACGATGTCAATAAACGTCTAGCAACTAACGATATTCACCTCGAAGTCACTGATAAGGTAAAAGAAAAATTAG
TTGACCTTGGCTACGATCCTAAAATGGGAGCTCGTCCATTACGTCGTACTATCCAAGACCACATTGAAGATGCCATTACA
GACTTCTATCTTGAAAATCCAAGCGAAAAAGATTTGAAAGCTGTTATGACAAGCAATGGTAAAATTATCATCAAATCTGC
TAAAAAAGTTGAAAAAGAAGAAACAACCGTTTCAGCAGAATCAGAATAA

Domains

Predicted by InterproScan.

AAA lid domain (AAA_lid_9)

(300-397)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(656-730)

ATPase family associated with various cellular activities (AAA) (AAA)

(162-281)

AAA domain (Cdc48 subfamily) (AAA_2)

(485-648)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

85.638

98.688

0.845
  clpE Streptococcus pneumoniae Rx1

84.197

98.819

0.832
  clpE Streptococcus pneumoniae D39

84.197

98.819

0.832
  clpE Streptococcus pneumoniae R6

84.197

98.819

0.832
  clpE Streptococcus pneumoniae TIGR4

84.197

98.819

0.832
  clpC Lactococcus lactis subsp. cremoris KW2

76.354

99.344

0.759
  clpC Bacillus subtilis subsp. subtilis str. 168

50.507

90.682

0.458
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

48.32

82.021

0.396
  clpC Streptococcus pneumoniae Rx1

46.802

84.121

0.394
  clpC Streptococcus pneumoniae D39

46.802

84.121

0.394
  clpC Streptococcus pneumoniae TIGR4

46.646

84.121

0.392
  clpC Streptococcus mutans UA159

47.504

81.496

0.387
  clpC Streptococcus thermophilus LMD-9

46.302

81.627

0.378
  clpC Streptococcus thermophilus LMG 18311

45.981

81.627

0.375

Multiple sequence alignment