Detailed information NTG0036162

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: GALLO_RS00295
• Genome accession: NC_013798
• Coordinates: 49789..50688 (+)
• Length: 299 a.a.
• NCBI ID: WP_009853198.1
• Uniprot ID: -
• Organism: Streptococcus gallolyticus UCN34
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 44789..55688

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GALLO_RS00270 (GALLO_0033)	-	44988..45437 (+)	450	WP_012961319.1	DUF523 domain-containing protein	-
GALLO_RS00275 (GALLO_0034)	purE	45437..45925 (+)	489	WP_009853194.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
GALLO_RS00280 (GALLO_0035)	purK	45912..46985 (+)	1074	WP_009853195.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
GALLO_RS00285 (GALLO_0036)	-	46996..48042 (+)	1047	WP_014619874.1	hypothetical protein	-
GALLO_RS00290 (GALLO_0037)	purB	48344..49642 (+)	1299	WP_012961320.1	adenylosuccinate lyase	-
GALLO_RS00295 (GALLO_0038)	comR	49789..50688 (+)	900	WP_009853198.1	helix-turn-helix domain-containing protein	Regulator
-	comS	50765..50809 (+)	45	-	-	Regulator
GALLO_RS00305 (GALLO_0039)	-	51930..52361 (+)	432	WP_012961321.1	low molecular weight protein-tyrosine-phosphatase	-
GALLO_RS00310 (GALLO_0040)	-	52381..52761 (+)	381	WP_012961322.1	membrane protein	-
GALLO_RS00315 (GALLO_0041)	-	52758..54551 (+)	1794	WP_012961323.1	acyltransferase family protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 34967.15 Da
• Isoelectric Point: 5.1732

>NTDB_id=36162 GALLO_RS00295 WP_009853198.1 49789..50688(+) (comR) [Streptococcus gallolyticus UCN34]
MEKFGIKVRALREKKGISREEFCGDETELSVRQLARIEKGQSVPTLNKVGYIAKVLGVTIGELTDGKNLELPTRYKELKY
LLLRTPTYGDKERLKRQTSYFDEISEKYYEVIPEEERLIIDCLQSKIDVHFSDDVNFGEGILNDYFDQVRRKKNFQINDL
ILIDLYFACLASAKSFVGIYSLDLYDELMECLLNQENLSPETSLILNNVLLNNVDLVLRFHRESFMKRIIIKSDTIMTSV
HDFQRRPVLSLVEWKYYLQFKKDFLAAQKSYSNAILFANLIGDTYLENKLIEEWNNDTT

Nucleotide

• Length: 900 bp

>NTDB_id=36162 GALLO_RS00295 WP_009853198.1 49789..50688(+) (comR) [Streptococcus gallolyticus UCN34]
TTGGAAAAGTTTGGGATTAAAGTACGTGCATTAAGAGAGAAAAAAGGGATTTCACGTGAAGAATTCTGTGGTGATGAAAC
AGAATTATCTGTGAGACAGCTAGCTAGAATTGAAAAAGGACAATCCGTCCCAACTCTTAATAAGGTGGGATATATTGCAA
AAGTATTAGGAGTAACTATTGGTGAGTTAACTGATGGTAAAAATTTAGAACTTCCCACTCGGTATAAGGAGTTAAAATAT
TTACTATTACGAACACCAACTTATGGGGATAAGGAACGTCTTAAGAGACAAACTTCATATTTTGATGAAATTTCAGAAAA
ATACTATGAAGTTATACCTGAAGAAGAACGCTTAATTATTGATTGTTTACAATCGAAGATTGATGTTCATTTTAGTGATG
ATGTTAATTTTGGTGAAGGAATTTTAAATGATTATTTTGACCAAGTTAGACGAAAGAAGAACTTTCAAATTAATGATTTG
ATTTTAATAGATTTATATTTTGCTTGCCTTGCTTCTGCTAAATCGTTTGTGGGAATCTATAGCTTAGATTTGTATGATGA
ATTAATGGAGTGTTTACTAAATCAAGAAAATCTTTCACCAGAAACTTCTTTGATTTTAAATAATGTTTTGTTAAATAATG
TAGATTTGGTTTTACGATTCCATAGAGAATCTTTTATGAAACGAATTATTATAAAAAGTGACACTATCATGACAAGTGTT
CATGATTTTCAAAGACGTCCAGTTTTAAGTTTAGTTGAGTGGAAATATTATTTACAATTTAAAAAAGATTTTTTAGCGGC
ACAAAAATCTTACTCCAATGCCATTTTATTTGCTAACTTAATTGGAGATACTTATTTGGAAAATAAGTTAATAGAAGAAT
GGAATAATGACACAACATGA

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (8-63)

• ComR tetratricopeptide (ComR_TPR) (72-294)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	72.474	95.987	0.696
comR	Streptococcus mutans UA159	54.515	100	0.545
comR	Streptococcus pyogenes MGAS8232	49.333	100	0.495
comR	Streptococcus pyogenes MGAS315	47.315	99.666	0.472
comR	Streptococcus suis P1/7	39.799	100	0.398
comR	Streptococcus suis 05ZYH33	39.799	100	0.398
comR	Streptococcus suis D9	37.71	99.331	0.375