Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E1E63_RS10085 Genome accession   NZ_CP039992
Coordinates   2010573..2011289 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Lr3     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2005573..2016289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1E63_RS10055 (E1E63_10055) - 2005790..2006416 (+) 627 WP_000522384.1 nitroreductase family protein -
  E1E63_RS10060 (E1E63_10060) - 2006777..2007562 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  E1E63_RS14140 (E1E63_10065) - 2008162..2008296 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  E1E63_RS10070 (E1E63_10070) - 2008532..2009095 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  E1E63_RS10075 (E1E63_10075) agrD 2009098..2009241 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  E1E63_RS10080 (E1E63_10080) agrC 2009271..2010554 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  E1E63_RS10085 (E1E63_10085) agrA 2010573..2011289 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E1E63_RS10090 (E1E63_10090) - 2011361..2011470 (+) 110 Protein_1923 hypothetical protein -
  E1E63_RS10095 (E1E63_10095) - 2011658..2012617 (-) 960 WP_001253308.1 carbohydrate kinase -
  E1E63_RS10100 (E1E63_10100) - 2012614..2014098 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  E1E63_RS10105 (E1E63_10105) - 2014247..2015197 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=361494 E1E63_RS10085 WP_000688492.1 2010573..2011289(+) (agrA) [Staphylococcus aureus strain Lr3]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=361494 E1E63_RS10085 WP_000688492.1 2010573..2011289(+) (agrA) [Staphylococcus aureus strain Lr3]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment