Detailed information NTG0361473

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: E1E63_RS06855
• Genome accession: NZ_CP039992
• Coordinates: 1370614..1371288 (-)
• Length: 224 a.a.
• NCBI ID: WP_000866106.1
• Uniprot ID: -
• Organism: Staphylococcus aureus strain Lr3
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1364845..1375040	1370614..1371288	within	0

Gene organization within MGE regions

Location: 1364845..1375040

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E1E63_RS06815 (E1E63_06815)	aph(3')-IIIa	1364845..1365639 (-)	795	WP_001096887.1	aminoglycoside O-phosphotransferase APH(3')-IIIa	-
E1E63_RS06820 (E1E63_06820)	sat4	1365732..1366267 (-)	536	Protein_1311	streptothricin N-acetyltransferase Sat4	-
E1E63_RS06825 (E1E63_06825)	-	1366264..1366899 (-)	636	Protein_1312	aminoglycoside 6-adenylyltransferase	-
E1E63_RS06830 (E1E63_06830)	-	1367040..1367714 (-)	675	WP_001105960.1	IS6 family transposase	-
E1E63_RS06835 (E1E63_06835)	-	1367771..1367947 (-)	177	Protein_1314	undecaprenyl-diphosphate phosphatase	-
E1E63_RS06840 (E1E63_06840)	-	1367961..1368698 (-)	738	WP_000369394.1	ABC transporter permease	-
E1E63_RS06845 (E1E63_06845)	-	1368691..1369620 (-)	930	WP_000793446.1	ABC transporter ATP-binding protein	-
E1E63_RS06850 (E1E63_06850)	-	1369736..1370617 (-)	882	Protein_1317	sensor histidine kinase	-
E1E63_RS06855 (E1E63_06855)	braR	1370614..1371288 (-)	675	WP_000866106.1	response regulator transcription factor	Regulator
E1E63_RS06860 (E1E63_06860)	-	1371428..1372102 (-)	675	WP_001105960.1	IS6 family transposase	-
E1E63_RS06865 (E1E63_06865)	msr(A)	1372576..1374042 (+)	1467	WP_000438874.1	ABC-F type ribosomal protection protein Msr(A)	-
E1E63_RS06870 (E1E63_06870)	-	1374141..1375040 (+)	900	WP_000196697.1	Mph(C) family macrolide 2'-phosphotransferase	-

Sequence

Protein

• Length: 224 a.a.
• Molecular weight: 25839.93 Da
• Isoelectric Point: 4.9884

>NTDB_id=361473 E1E63_RS06855 WP_000866106.1 1370614..1371288(-) (braR) [Staphylococcus aureus strain Lr3]
MKVLIVEDDLVIGKMLAEELKKWQLEPILIEGFNHVMDAFNTNAPELVLLDINLPAFNGYHWCQEIRKVSTVPIIFISSR
NDSMDQVMAMQMGADDFIEKPFNMTVTITKIQALLRRTYDFTTQVNNLTVDDCELLLDAAKLKFNEETIDLTHTELQIMH
SLFQNKGKFVSRNALIEKCWESEHFIDDNTLAVNITRLRKKLQKLGLTDFIETKKNVGYRVGDV

Nucleotide

• Length: 675 bp

>NTDB_id=361473 E1E63_RS06855 WP_000866106.1 1370614..1371288(-) (braR) [Staphylococcus aureus strain Lr3]
ATGAAAGTATTAATCGTAGAGGATGACTTAGTTATCGGGAAGATGCTTGCTGAAGAGCTCAAGAAGTGGCAGCTAGAACC
GATCTTAATAGAAGGTTTCAATCATGTAATGGATGCCTTCAACACGAATGCACCGGAACTTGTGTTACTCGATATTAATT
TACCTGCCTTCAATGGTTATCACTGGTGTCAGGAGATTCGTAAAGTTTCTACTGTACCGATTATATTTATTAGTTCGCGT
AACGACAGTATGGATCAAGTAATGGCGATGCAGATGGGTGCGGATGATTTCATTGAGAAGCCATTTAATATGACTGTTAC
AATTACTAAGATTCAAGCACTATTACGCCGCACGTATGATTTCACCACTCAAGTTAATAATTTAACAGTAGATGATTGCG
AGTTACTACTTGATGCAGCAAAGCTTAAATTTAATGAAGAAACCATAGACCTGACACACACTGAATTGCAAATCATGCAT
AGCTTATTCCAGAACAAGGGCAAATTCGTCAGTCGTAATGCGTTAATCGAAAAATGCTGGGAATCAGAACACTTCATTGA
TGACAATACGCTTGCTGTCAACATTACACGTTTACGCAAAAAGCTACAAAAACTAGGACTTACAGATTTTATCGAAACGA
AGAAAAATGTCGGATATCGTGTAGGTGACGTATGA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-220)

• Response regulator receiver domain (Response_reg) (3-111)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	66.516	98.661	0.656