Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   E8M05_RS06455 Genome accession   NZ_CP039457
Coordinates   1221044..1222273 (-) Length   409 a.a.
NCBI ID   WP_003065195.1    Uniprot ID   A0AAW6Y801
Organism   Streptococcus pasteurianus strain WUSP067     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1216044..1227273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E8M05_RS06425 (E8M05_06415) - 1216098..1216745 (+) 648 WP_048791465.1 endonuclease III domain-containing protein -
  E8M05_RS06430 (E8M05_06420) - 1216854..1217522 (+) 669 WP_039694591.1 YoaK family protein -
  E8M05_RS06435 (E8M05_06425) - 1217604..1218212 (-) 609 WP_058692219.1 GyrI-like domain-containing protein -
  E8M05_RS06440 (E8M05_06430) - 1218271..1219170 (-) 900 WP_117508652.1 YafY family protein -
  E8M05_RS11215 - 1219221..1219448 (-) 228 WP_325052498.1 homocysteine S-methyltransferase family protein -
  E8M05_RS06445 (E8M05_06435) - 1219472..1220215 (-) 744 Protein_1175 amino acid permease -
  E8M05_RS06450 (E8M05_06440) yihA 1220440..1221033 (-) 594 WP_136596442.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  E8M05_RS06455 (E8M05_06445) clpX 1221044..1222273 (-) 1230 WP_003065195.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  E8M05_RS06460 (E8M05_06450) - 1222306..1222476 (-) 171 WP_136596443.1 hypothetical protein -
  E8M05_RS06465 (E8M05_06455) - 1222492..1222986 (-) 495 WP_009854361.1 dihydrofolate reductase -
  E8M05_RS06470 (E8M05_06460) - 1223074..1223913 (-) 840 WP_069788935.1 thymidylate synthase -
  E8M05_RS06475 (E8M05_06465) - 1224234..1225412 (+) 1179 WP_069788934.1 hydroxymethylglutaryl-CoA synthase -
  E8M05_RS06480 (E8M05_06470) - 1225387..1226670 (+) 1284 WP_136596444.1 hydroxymethylglutaryl-CoA reductase, degradative -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45140.74 Da        Isoelectric Point: 4.5644

>NTDB_id=358794 E8M05_RS06455 WP_003065195.1 1221044..1222273(-) (clpX) [Streptococcus pasteurianus strain WUSP067]
MVGNRTNDVKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLATLDEYVVGQDR
AKRALAVAVYNHYKRVSFAESRNEEDVDLQKSNILMIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADFNIERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEDIVKQRLGEKVIGFGQNNRKIDENASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLTADDLVRI
LTEPRNALVKQYQTLLSYDGVELEFDKDALQAIANKAIERKTGARGLRSIIEETMMDIMFEIPSQEEVTKVRVTKAAVEG
KDKPILEIA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=358794 E8M05_RS06455 WP_003065195.1 1221044..1222273(-) (clpX) [Streptococcus pasteurianus strain WUSP067]
ATGGTTGGAAATCGAACAAATGATGTAAAAGTTTATTGCTCATTCTGTGGAAAAAGCCAAGATGAAGTAAAAAAAATCAT
TGCAGGAAACAATGTTTTTATCTGTAATGAGTGCGTGGCTTTGTCACAAGAAATTATCAAAGAAGAACTTGCTGAAGAAG
TTCTTGCAGATTTAGCGGAAGTTCCAAAACCTAAAGAGTTGTTAGCAACTCTTGACGAATATGTCGTTGGTCAAGACCGT
GCCAAACGCGCGCTTGCCGTAGCTGTTTATAACCATTACAAACGTGTTTCTTTTGCGGAAAGTCGCAACGAAGAAGATGT
TGATTTGCAAAAATCAAACATTTTGATGATTGGTCCCACAGGTTCAGGAAAAACATTCCTAGCTCAAACTTTGGCTAAAA
CATTGAATGTACCGTTTGCGATTGCTGATGCGACATCATTGACAGAAGCAGGATACGTTGGTGAAGATGTTGAAAATATC
CTTTTGAAATTAATTCAAGCAGCTGATTTTAATATCGAACGCGCAGAACGCGGTATCATTTACGTGGACGAAATTGATAA
AATCGCTAAAAAAGGCGAAAATGTCTCAATTACACGTGATGTTTCAGGTGAAGGTGTTCAACAAGCACTTCTTAAAATCA
TTGAAGGAACAGTTGCTAGCGTACCACCTCAAGGTGGACGTAAGCACCCTAACCAAGAAATGATTCAAATTGATACTAAA
AATATCCTATTCATTGTCGGCGGTGCTTTTGATGGTATCGAGGATATTGTCAAACAACGTTTAGGTGAAAAGGTTATCGG
TTTTGGCCAAAATAACCGTAAAATTGATGAAAATGCTTCTTATATGCAAGAAATCATTTCAGAAGATATTCAAAAATTTG
GCTTGATTCCAGAGTTTATCGGACGTTTGCCAGTTGTAGCGGCACTTGAACAGTTGACGGCTGATGATTTGGTTCGTATC
TTGACAGAACCACGTAATGCCTTGGTTAAACAATATCAAACACTATTATCATATGATGGTGTTGAACTAGAATTTGATAA
AGATGCTTTGCAAGCTATTGCTAACAAAGCCATTGAACGTAAGACAGGAGCTCGTGGTTTACGCTCAATTATTGAGGAAA
CTATGATGGATATCATGTTTGAAATTCCTAGCCAAGAAGAAGTGACCAAGGTTCGTGTCACTAAAGCGGCTGTTGAAGGC
AAAGATAAACCAATTTTGGAAATTGCGTAA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-391)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

89.731

100

0.897
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.354

98.044

0.572

Multiple sequence alignment