Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   GR129_RS19705 Genome accession   NZ_CP047144
Coordinates   4436045..4437169 (-) Length   374 a.a.
NCBI ID   WP_037660305.1    Uniprot ID   A0A1X4GT45
Organism   Streptomyces sp. HF10     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4431045..4442169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GR129_RS19680 (GR129_19680) cseB 4431902..4432606 (-) 705 WP_159703736.1 two-component system response regulator CseB -
  GR129_RS19685 (GR129_19685) - 4432658..4433269 (-) 612 WP_159708427.1 hypothetical protein -
  GR129_RS19690 (GR129_19690) - 4433311..4433850 (-) 540 WP_037660309.1 SigE family RNA polymerase sigma factor -
  GR129_RS19695 (GR129_19695) - 4434132..4435007 (-) 876 WP_145487924.1 A/G-specific adenine glycosylase -
  GR129_RS19700 (GR129_19700) - 4435187..4436017 (+) 831 WP_201300634.1 hypothetical protein -
  GR129_RS19705 (GR129_19705) disA 4436045..4437169 (-) 1125 WP_037660305.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  GR129_RS19710 (GR129_19710) radA/sms 4437250..4438659 (-) 1410 WP_145487922.1 DNA repair protein RadA Machinery gene
  GR129_RS19715 (GR129_19715) - 4438861..4440699 (+) 1839 WP_236576400.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 39932.68 Da        Isoelectric Point: 4.9187

>NTDB_id=357611 GR129_RS19705 WP_037660305.1 4436045..4437169(-) (disA) [Streptomyces sp. HF10]
MAANDRAAAPGKSGGSAGSDGLMRAALSAVAPGTAMRDGLERILRGNTGGLIVLGSDKTVEAMCTGGFVLDVEFAATRLR
ELCKLDGGIVLSSDLSKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVSAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLEELIA
GVEPDRELVVRDYVPEPTAKRSRTVEEALSELNALTQAELIEVGTVARALGYTGSPETLDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=357611 GR129_RS19705 WP_037660305.1 4436045..4437169(-) (disA) [Streptomyces sp. HF10]
GTGGCAGCCAACGACCGGGCAGCAGCTCCCGGAAAGTCCGGTGGGAGTGCCGGTTCCGATGGCCTGATGCGCGCTGCCCT
GAGCGCCGTGGCACCCGGTACGGCCATGCGGGACGGCCTGGAGCGCATCCTGCGCGGCAACACCGGCGGCCTGATCGTGC
TCGGCTCCGACAAGACCGTCGAGGCGATGTGCACCGGCGGCTTCGTGCTGGACGTGGAGTTCGCCGCGACCCGGCTGCGG
GAGCTGTGCAAGCTGGACGGCGGCATCGTGCTGTCCTCGGACCTCTCGAAGATCCTGCGCGCGGGCGTCCAGCTGGTCCC
GGACCCGACCATCCCCACCGAGGAGACGGGCACCCGGCACCGGACGGCGGACCGGGTGAGCAAGCAGGTCGGCTTCCCCG
TCGTCTCCGTGTCCCAGTCGATGCGGCTGATCGCGCTCTACGTCGACGGTCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCGAACCAGGCGCTGGCCACGCTGGAGCGGTACAAGCTCCGCCTGGACGAGGTGGCGGGCACGCTGTC
GGCGCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTGTCCGCCGTCGCACAGCGTCTGGAGATGGTGCGCCGGATCG
CCACCGAGATCGCCGAGTACGTGGTGGAGCTGGGCACCGACGGCCGGCTGCTCGCGCTCCAGCTGGAGGAGCTGATCGCG
GGGGTCGAGCCGGACCGGGAGCTGGTCGTACGGGACTATGTGCCCGAGCCGACCGCGAAGCGCTCCCGCACGGTGGAGGA
GGCCCTGTCCGAGCTGAACGCGCTCACCCAGGCCGAGCTGATCGAGGTCGGCACGGTGGCGCGGGCGCTGGGCTACACCG
GGTCGCCCGAGACCCTGGACTCCGCGGTGTCCCCGCGGGGCTTCCGGCTGCTGGCCAAGGTGCCGCGGCTGCCGGGGGCG
ATCATCGACCGGCTGGTGGAGCACTTCGGCGGACTGCAGAAGCTGTTGGCCGCGAGTGTGGACGATCTGCAGACGGTGGA
CGGTGTGGGCGAGGCGCGGGCGAGGAGCGTGCGGGAGGGACTCTCGCGGCTGGCCGAGTCCTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

Helix-hairpin-helix motif (HHH_2)

(324-359)

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1X4GT45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.143

93.583

0.422