Detailed information NTG0357357

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E1950_RS13250
• Genome accession: NZ_CP039162
• Coordinates: 2591783..2592670 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain Lr12
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2586783..2597670

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E1950_RS13215 (E1950_13500)	-	2586802..2586894 (+)	93	WP_010956583.1	hypothetical protein	-
E1950_RS13220 (E1950_13505)	-	2587002..2587499 (-)	498	WP_001065268.1	glutathione peroxidase	-
E1950_RS13225 (E1950_13510)	-	2587509..2587769 (-)	261	WP_001791974.1	hypothetical protein	-
E1950_RS13235 (E1950_13520)	-	2588151..2588264 (-)	114	Protein_2555	hypothetical protein	-
E1950_RS13240 (E1950_13525)	-	2588923..2590923 (-)	2001	WP_000776751.1	ABC transporter permease	-
E1950_RS13245 (E1950_13530)	-	2590920..2591675 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E1950_RS13250 (E1950_13535)	braS	2591783..2592670 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E1950_RS13255 (E1950_13540)	braR	2592681..2593346 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E1950_RS13260 (E1950_13545)	-	2593372..2593572 (-)	201	WP_000604730.1	hypothetical protein	-
E1950_RS13265 (E1950_13550)	-	2593770..2595194 (+)	1425	WP_000953755.1	alkaline phosphatase	-
E1950_RS14640 (E1950_13555)	-	2595254..2595355 (-)	102	WP_000731976.1	SE2200 family small protein	-
E1950_RS13275 (E1950_13560)	-	2595477..2595932 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E1950_RS13280 (E1950_13565)	-	2596177..2596938 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=357357 E1950_RS13250 WP_000143425.1 2591783..2592670(-) (braS) [Staphylococcus aureus strain Lr12]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=357357 E1950_RS13250 WP_000143425.1 2591783..2592670(-) (braS) [Staphylococcus aureus strain Lr12]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1