Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E1950_RS10050 Genome accession   NZ_CP039162
Coordinates   1977833..1978549 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain Lr12     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1972833..1983549
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1950_RS10020 (E1950_10205) - 1973050..1973676 (+) 627 WP_000522381.1 nitroreductase family protein -
  E1950_RS10025 (E1950_10210) - 1974037..1974822 (+) 786 WP_000867951.1 carbon-nitrogen family hydrolase -
  E1950_RS14605 (E1950_10215) - 1975422..1975556 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  E1950_RS10035 (E1950_10220) - 1975792..1976355 (+) 564 WP_001105696.1 accessory gene regulator AgrB -
  E1950_RS10040 (E1950_10225) agrD 1976358..1976501 (+) 144 WP_001094921.1 cyclic lactone autoinducer peptide AgrD -
  E1950_RS10045 (E1950_10230) agrC 1976531..1977814 (+) 1284 WP_000447888.1 quorum-sensing sensor histidine kinase AgrC -
  E1950_RS10050 (E1950_10235) agrA 1977833..1978549 (+) 717 WP_000688492.1 quorum-sensing response regulator AgrA Regulator
  E1950_RS10055 (E1950_10240) - 1978621..1978730 (+) 110 Protein_1942 hypothetical protein -
  E1950_RS10060 (E1950_10245) - 1978918..1979877 (-) 960 WP_001253312.1 carbohydrate kinase -
  E1950_RS10065 (E1950_10250) - 1979874..1981358 (-) 1485 WP_000141432.1 sucrose-6-phosphate hydrolase -
  E1950_RS10070 (E1950_10255) - 1981507..1982457 (-) 951 WP_000790331.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=357353 E1950_RS10050 WP_000688492.1 1977833..1978549(+) (agrA) [Staphylococcus aureus strain Lr12]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=357353 E1950_RS10050 WP_000688492.1 1977833..1978549(+) (agrA) [Staphylococcus aureus strain Lr12]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGACCCA
GTTGGTAACATTATTTTCGTTACGAGTCACAGTGAACTTACCTATTTAACATTTGTCTACAAAGTTGCAGCGATGGATTT
TATTTTTAAAGATGATCCAGCAGAATTAAGAACTCGAATTATAGATTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCATCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment