Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   E1950_RS04635 Genome accession   NZ_CP039162
Coordinates   907786..908772 (+) Length   328 a.a.
NCBI ID   WP_000959282.1    Uniprot ID   A0A7U7EXT8
Organism   Staphylococcus aureus strain Lr12     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 902786..913772
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E1950_RS04610 (E1950_04680) opp4B 903000..903962 (+) 963 WP_000915997.1 oligopeptide ABC transporter permease -
  E1950_RS04615 (E1950_04685) opp4C 903974..904855 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  E1950_RS04620 (E1950_04690) trpS 904897..905886 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  E1950_RS04625 (E1950_04695) spxA 906180..906575 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  E1950_RS04630 (E1950_04700) mecA 906946..907665 (+) 720 WP_001217728.1 adaptor protein MecA -
  E1950_RS04635 (E1950_04705) coiA 907786..908772 (+) 987 WP_000959282.1 competence protein CoiA Machinery gene
  E1950_RS04640 (E1950_04710) pepF 908820..910628 (+) 1809 WP_138118336.1 oligoendopeptidase F -
  E1950_RS04645 (E1950_04715) yjbH 911088..911894 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  E1950_RS04650 (E1950_04720) - 911917..912282 (-) 366 WP_000214070.1 truncated hemoglobin YjbI -
  E1950_RS04655 (E1950_04725) - 912386..912979 (-) 594 WP_000224619.1 CYTH domain-containing protein -
  E1950_RS04660 (E1950_04730) - 913165..913512 (+) 348 WP_001242103.1 hypothetical protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38878.55 Da        Isoelectric Point: 9.5714

>NTDB_id=357328 E1950_RS04635 WP_000959282.1 907786..908772(+) (coiA) [Staphylococcus aureus strain Lr12]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=357328 E1950_RS04635 WP_000959282.1 907786..908772(+) (coiA) [Staphylococcus aureus strain Lr12]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

100

100

1
  coiA Staphylococcus aureus MW2

97.561

100

0.976

Multiple sequence alignment