Detailed information NTG0357275

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: E5491_RS14705
• Genome accession: NZ_CP039156
• Coordinates: 2794795..2795682 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143425.1
• Uniprot ID: A0A389PV50
• Organism: Staphylococcus aureus strain WCUH29
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2789795..2800682

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E5491_RS14670 (E5491_14745)	-	2789814..2789906 (+)	93	WP_010956583.1	hypothetical protein	-
E5491_RS14675 (E5491_14750)	-	2790014..2790511 (-)	498	WP_001065268.1	glutathione peroxidase	-
E5491_RS14680 (E5491_14755)	-	2790521..2790781 (-)	261	WP_001791974.1	hypothetical protein	-
E5491_RS14690 (E5491_14765)	-	2791163..2791276 (-)	114	Protein_2766	hypothetical protein	-
E5491_RS14695 (E5491_14770)	-	2791935..2793935 (-)	2001	WP_000776751.1	ABC transporter permease	-
E5491_RS14700 (E5491_14775)	-	2793932..2794687 (-)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
E5491_RS14705 (E5491_14780)	braS	2794795..2795682 (-)	888	WP_000143425.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
E5491_RS14710 (E5491_14785)	braR	2795693..2796358 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
E5491_RS14715 (E5491_14790)	-	2796384..2796584 (-)	201	WP_000604730.1	hypothetical protein	-
E5491_RS14720 (E5491_14795)	-	2796782..2798206 (+)	1425	WP_000953755.1	alkaline phosphatase	-
E5491_RS15475 (E5491_14800)	-	2798266..2798367 (-)	102	WP_000731976.1	SE2200 family small protein	-
E5491_RS14730 (E5491_14805)	-	2798489..2798944 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
E5491_RS14735 (E5491_14810)	-	2799189..2799950 (-)	762	WP_000323441.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34006.28 Da
• Isoelectric Point: 6.0874

>NTDB_id=357275 E5491_RS14705 WP_000143425.1 2794795..2795682(-) (braS) [Staphylococcus aureus strain WCUH29]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLETALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLHVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=357275 E5491_RS14705 WP_000143425.1 2794795..2795682(-) (braS) [Staphylococcus aureus strain WCUH29]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAACTGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTTAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTACACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A389PV50

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	100	100	1