Detailed information NTG0355827

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SaO82_RS13540
• Genome accession: NZ_CP038819
• Coordinates: 2658778..2659665 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain O82
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2653778..2664665

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SaO82_RS13505	-	2653780..2653872 (+)	93	WP_010956583.1	hypothetical protein	-
SaO82_RS13510 (SaO82_2518)	-	2653980..2654477 (-)	498	WP_001065267.1	glutathione peroxidase	-
SaO82_RS13515	-	2654487..2654747 (-)	261	WP_078064828.1	hypothetical protein	-
SaO82_RS13525	-	2655129..2655242 (-)	114	WP_072491147.1	hypothetical protein	-
SaO82_RS13530 (SaO82_2520)	-	2655918..2657918 (-)	2001	WP_136142692.1	ABC transporter permease	-
SaO82_RS13535 (SaO82_2521)	-	2657915..2658670 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
SaO82_RS13540 (SaO82_2522)	braS	2658778..2659665 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SaO82_RS13545 (SaO82_2523)	braR	2659676..2660341 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SaO82_RS13550 (SaO82_2524)	-	2660367..2660567 (-)	201	WP_000604725.1	hypothetical protein	-
SaO82_RS13555 (SaO82_2525)	-	2660765..2662189 (+)	1425	WP_000953759.1	alkaline phosphatase	-
SaO82_RS14265	-	2662249..2662350 (-)	102	WP_000731972.1	SE2200 family small protein	-
SaO82_RS13565 (SaO82_2526)	-	2662472..2662927 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SaO82_RS13570 (SaO82_2527)	-	2663172..2663933 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=355827 SaO82_RS13540 WP_000143420.1 2658778..2659665(-) (braS) [Staphylococcus aureus strain O82]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=355827 SaO82_RS13540 WP_000143420.1 2658778..2659665(-) (braS) [Staphylococcus aureus strain O82]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993