Detailed information NTG0355822

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SaO82_RS09960
• Genome accession: NZ_CP038819
• Coordinates: 1968844..1969887 (-)
• Length: 347 a.a.
• NCBI ID: WP_001017131.1
• Uniprot ID: A0A0D1IMN4
• Organism: Staphylococcus aureus strain O82
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1963844..1974887

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SaO82_RS09930 (SaO82_1855)	-	1964265..1965521 (-)	1257	WP_078071269.1	aminopeptidase	-
SaO82_RS09935 (SaO82_1856)	-	1965524..1965724 (-)	201	WP_000180460.1	DUF1128 family protein	-
SaO82_RS09940 (SaO82_1857)	-	1965871..1966335 (+)	465	WP_136142647.1	low molecular weight protein-tyrosine-phosphatase	-
SaO82_RS09945 (SaO82_1858)	-	1966342..1966617 (+)	276	WP_000428172.1	YtxH domain-containing protein	-
SaO82_RS09950 (SaO82_1859)	-	1966895..1968112 (+)	1218	WP_000037081.1	YihY/virulence factor BrkB family protein	-
SaO82_RS09955 (SaO82_1860)	vraR	1968225..1968854 (-)	630	WP_000153530.1	two-component system response regulator VraR	Regulator
SaO82_RS09960 (SaO82_1861)	vraS	1968844..1969887 (-)	1044	WP_001017131.1	sensor histidine kinase	Regulator
SaO82_RS09965 (SaO82_1862)	liaF	1969884..1970585 (-)	702	WP_000149070.1	cell wall-active antibiotics response protein LiaF	-
SaO82_RS09970 (SaO82_1863)	-	1970600..1970986 (-)	387	WP_001110179.1	hypothetical protein	-
SaO82_RS09975 (SaO82_1864)	map	1971203..1971961 (-)	759	WP_000636142.1	type I methionyl aminopeptidase	-
SaO82_RS09980 (SaO82_1865)	-	1972488..1973474 (+)	987	WP_000999713.1	aromatic acid exporter family protein	-
SaO82_RS09985 (SaO82_1866)	-	1973663..1974076 (-)	414	WP_025174666.1	hypothetical protein	-
SaO82_RS09990	-	1974105..1974215 (-)	111	WP_001790257.1	hypothetical protein	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40044.52 Da
• Isoelectric Point: 6.0577

>NTDB_id=355822 SaO82_RS09960 WP_001017131.1 1968844..1969887(-) (vraS) [Staphylococcus aureus strain O82]
MNHYIRTIGSMLILVYSMLAAFLFIDKVFVNIIYFQGMFYTQIFGIPVFLFLNLIIILLCIIVGSVLAYKINQQNDWIKT
QIERSMEGETVGINDQNIEIYSETLDLYHTLVPLNQELHKLRLKTQNLTNENYNINDVKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPILEKMVQDSQLEMRALLLHLRPLGLKDKSLGEGIKDLVIDLQKKVPMKVVHEI
QDFKVPKGIEDHLFRITQEAISNTLRHSNGTKVTVELFNKDDYLLLRIQDNGKGFNVDEKLEQSYGLKNMRERALEIGAT
FHIVSLPDSGTRIEVKAPLNKEDSYDD

Nucleotide

• Length: 1044 bp

>NTDB_id=355822 SaO82_RS09960 WP_001017131.1 1968844..1969887(-) (vraS) [Staphylococcus aureus strain O82]
ATGAACCACTACATTAGAACAATTGGTTCAATGCTCATCTTAGTATATAGCATGCTAGCTGCATTTCTGTTCATCGATAA
AGTTTTTGTAAATATCATCTATTTTCAAGGTATGTTTTATACACAAATATTCGGAATACCAGTCTTTTTATTTTTAAATC
TCATCATCATTTTATTGTGTATTATTGTTGGTTCGGTACTCGCTTACAAAATCAATCAGCAAAATGATTGGATTAAGACG
CAAATTGAGCGTTCAATGGAAGGCGAAACAGTTGGCATTAATGATCAAAATATAGAAATATATAGTGAAACGTTAGATTT
ATACCATACACTCGTACCTTTAAATCAAGAATTGCATAAGTTGCGACTTAAAACTCAAAACTTAACCAATGAAAATTATA
ATATTAATGATGTGAAAGTTAAAAAGATTATTGAAGATGAACGTCAAAGACTAGCACGAGAACTTCACGATTCTGTTAGT
CAGCAACTTTTTGCGGCAAGTATGATGCTATCTGCTATCAAAGAAACGAAGTTAGAACCACCATTAGACCAACAAATTCC
GATTTTAGAGAAAATGGTTCAAGATTCGCAGTTAGAAATGCGTGCTTTGCTGTTACATTTAAGACCGCTTGGTTTAAAAG
ACAAATCTTTAGGTGAGGGTATTAAAGATTTAGTTATTGATTTACAAAAAAAAGTGCCAATGAAAGTTGTGCATGAAATT
CAAGATTTTAAAGTGCCTAAAGGTATTGAAGATCATTTGTTCAGAATTACACAGGAAGCAATTTCGAATACATTGCGTCA
TTCAAACGGTACAAAAGTGACAGTAGAATTGTTTAATAAAGACGATTATTTATTGTTGAGAATTCAAGACAATGGTAAAG
GTTTTAATGTTGATGAAAAATTAGAACAAAGTTATGGACTTAAAAATATGCGTGAAAGAGCTTTGGAAATTGGTGCAACG
TTCCATATTGTATCATTGCCAGATTCGGGTACACGTATCGAGGTGAAAGCACCTTTAAATAAGGAGGATTCGTATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

• Histidine kinase (HisKA_3) (147-210)

3D structure

• AlphaFold DB: A0A0D1IMN4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	100	100	1