Detailed information NTG0355658

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: AGP54_RS02845
• Genome accession: NZ_CP038809
• Coordinates: 506515..507588 (+)
• Length: 357 a.a.
• NCBI ID: WP_000796095.1
• Uniprot ID: A0A0E1EG10
• Organism: Streptococcus agalactiae strain SS1168
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 501515..512588

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
AGP54_RS02815 (AGP54_02900)	-	502408..503472 (+)	1065	WP_000021307.1	MmcQ/YjbR family DNA-binding protein	-
AGP54_RS02820 (AGP54_02905)	asnA	503586..504578 (+)	993	WP_000748011.1	aspartate--ammonia ligase	-
AGP54_RS02825 (AGP54_02910)	-	504611..505072 (-)	462	WP_220298507.1	bacteriocin transport accessory protein	-
AGP54_RS02830 (AGP54_02920)	rsmD	505202..505741 (+)	540	WP_001266830.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
AGP54_RS02835 (AGP54_02925)	-	505753..506043 (+)	291	WP_000384889.1	hypothetical protein	-
AGP54_RS02840 (AGP54_02930)	coaD	506040..506525 (+)	486	WP_000161892.1	pantetheine-phosphate adenylyltransferase	-
AGP54_RS02845 (AGP54_02935)	sepM	506515..507588 (+)	1074	WP_000796095.1	SepM family pheromone-processing serine protease	Regulator
AGP54_RS02850 (AGP54_02940)	-	507663..508995 (+)	1333	Protein_479	bifunctional UDP-sugar hydrolase/5'-nucleotidase	-
AGP54_RS02855 (AGP54_02945)	-	509064..509642 (+)	579	WP_001224500.1	YutD-like domain-containing protein	-
AGP54_RS02860 (AGP54_02950)	rlmN	509693..510799 (+)	1107	WP_001124990.1	23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN	-
AGP54_RS02865 (AGP54_02955)	-	510799..511314 (+)	516	WP_000919802.1	VanZ family protein	-

Sequence

Protein

• Length: 357 a.a.
• Molecular weight: 39199.43 Da
• Isoelectric Point: 10.4385

>NTDB_id=355658 AGP54_RS02845 WP_000796095.1 506515..507588(+) (sepM) [Streptococcus agalactiae strain SS1168]
MKNRDPKRKHKSLLGLLKWWIIGFAFLLLVLASLVVRLPYYLEMPGGAYDIRSVLKVNKKADKAKGSYNFVAVSVSQATP
AQVLYAWLTPFTELSSKEETTGGFSNDDYLRINQFYMETSQNESIYQALKLANKQVSLTYKGVYVLNLAKNSTFKDRLHL
ADTVTGVNGKSFKNSSQLIKYVAALHLGDKVKVQYTSQGKKKESVGKVIKLSNGKNGIGIGLTDHTEVLSDVPVDFNTEG
VGGPSAGLMFTLAIYDQLVKEDLRKGRKIAGTGTIEQNGHVGDIGGAGLKVVSAAKKGMDIFFVPNNPIDKNAKKGKTKV
QTNYQEAKAAAKRLGTKMKIVPVQNVQQAIDYLKKTK

Nucleotide

• Length: 1074 bp

>NTDB_id=355658 AGP54_RS02845 WP_000796095.1 506515..507588(+) (sepM) [Streptococcus agalactiae strain SS1168]
GTGAAGAATAGAGATCCAAAAAGAAAACATAAAAGTTTACTAGGTCTGCTTAAATGGTGGATTATAGGTTTTGCTTTTTT
ATTGTTAGTATTAGCAAGCCTTGTAGTGAGACTACCTTATTATTTGGAAATGCCAGGTGGAGCTTATGATATCCGTTCGG
TATTGAAAGTGAATAAAAAGGCTGATAAAGCTAAGGGTTCGTACAATTTTGTAGCGGTATCTGTCAGTCAAGCAACGCCA
GCTCAGGTTCTTTATGCTTGGTTAACTCCTTTTACAGAATTATCTAGTAAAGAGGAGACAACAGGTGGCTTTAGTAATGA
CGATTATCTCAGAATTAATCAATTCTACATGGAGACTTCTCAAAATGAGTCCATCTATCAAGCTTTAAAGTTAGCTAATA
AGCAAGTATCTCTTACTTATAAAGGAGTTTATGTGCTTAACTTAGCTAAAAATTCGACATTTAAAGATAGATTACATTTA
GCTGATACAGTCACAGGAGTTAATGGCAAAAGTTTCAAAAATTCTTCTCAACTTATCAAATATGTTGCAGCTCTTCATCT
AGGTGATAAAGTAAAGGTACAATACACAAGTCAAGGTAAAAAGAAAGAATCAGTTGGTAAAGTTATTAAACTATCAAACG
GTAAAAATGGTATTGGTATCGGTTTGACAGACCATACAGAAGTATTATCTGATGTTCCTGTGGACTTTAATACTGAAGGT
GTTGGAGGACCAAGTGCAGGTTTAATGTTTACTTTAGCGATTTACGACCAATTGGTTAAAGAAGATTTACGTAAAGGACG
TAAGATTGCAGGTACTGGTACTATTGAGCAAAATGGGCATGTTGGCGATATTGGTGGAGCAGGTTTGAAAGTTGTTTCAG
CGGCTAAAAAAGGAATGGATATTTTCTTTGTTCCTAATAATCCGATCGATAAAAATGCTAAAAAAGGCAAAACAAAGGTT
CAGACGAATTATCAAGAGGCAAAAGCAGCAGCTAAGCGATTAGGTACGAAGATGAAAATTGTACCAGTTCAAAATGTTCA
GCAAGCTATTGATTATTTGAAAAAAACAAAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (137-203)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (242-307)

3D structure

• AlphaFold DB: A0A0E1EG10

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	69.322	94.958	0.658