Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   E5Z44_RS11620 Genome accession   NZ_CP038807
Coordinates   2442557..2443273 (+) Length   238 a.a.
NCBI ID   WP_002461418.1    Uniprot ID   -
Organism   Staphylococcus lugdunensis strain APC 3758     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2437557..2448273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  E5Z44_RS11595 (E5Z44_11740) - 2438351..2438974 (+) 624 WP_002461413.1 nitroreductase family protein -
  E5Z44_RS11600 (E5Z44_11745) - 2439109..2439894 (+) 786 WP_002492308.1 carbon-nitrogen family hydrolase -
  E5Z44_RS11605 (E5Z44_11750) - 2440522..2441088 (+) 567 WP_037540641.1 accessory gene regulator AgrB -
  E5Z44_RS11610 (E5Z44_11755) agrD 2441091..2441234 (+) 144 WP_002461416.1 cyclic lactone autoinducer peptide AgrD -
  E5Z44_RS11615 (E5Z44_11760) agrC 2441255..2442544 (+) 1290 WP_002461417.1 quorum-sensing sensor histidine kinase AgrC -
  E5Z44_RS11620 (E5Z44_11765) agrA 2442557..2443273 (+) 717 WP_002461418.1 quorum-sensing response regulator AgrA Regulator
  E5Z44_RS11625 (E5Z44_11770) - 2443365..2444339 (-) 975 WP_002492304.1 carbohydrate kinase family protein -
  E5Z44_RS11630 (E5Z44_11775) - 2444340..2445824 (-) 1485 WP_002492299.1 sucrose-6-phosphate hydrolase -
  E5Z44_RS11635 (E5Z44_11780) - 2445924..2446874 (-) 951 WP_002461422.1 LacI family DNA-binding transcriptional regulator -
  E5Z44_RS11640 (E5Z44_11785) - 2446974..2448218 (-) 1245 WP_002477917.1 ammonium transporter -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27935.92 Da        Isoelectric Point: 5.9140

>NTDB_id=355558 E5Z44_RS11620 WP_002461418.1 2442557..2443273(+) (agrA) [Staphylococcus lugdunensis strain APC 3758]
MKIYICEDDVKQRENMVEIINNYIMIEEKPMEIALATDNPYEILKMSKENEDVGCYFLDIQLEADINGIKLGSEIRKYDP
IGNIIFVTSHSELTYLTFVYKVSAMDFIFKDDPAELKTRIIDCLETAHTRLKLLSKERTVETIELKRGSNSVYVQYDEVM
FFESSTNSHRLIAHLDNRQIEFYGNLKQISQIDDRFFRCHNSFVVNRHNISSINSKERVVYFKNGEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=355558 E5Z44_RS11620 WP_002461418.1 2442557..2443273(+) (agrA) [Staphylococcus lugdunensis strain APC 3758]
ATGAAGATTTACATTTGTGAAGATGATGTTAAACAACGTGAAAATATGGTTGAGATCATCAATAACTATATCATGATTGA
AGAAAAACCAATGGAAATTGCTTTAGCTACAGATAATCCTTATGAAATTTTAAAAATGTCAAAGGAAAATGAGGATGTTG
GTTGTTATTTTTTAGATATTCAATTAGAAGCTGACATAAACGGTATCAAGTTAGGTAGCGAAATAAGAAAGTATGATCCG
ATAGGTAACATAATTTTTGTTACAAGTCATAGTGAGCTGACATATTTAACTTTTGTTTACAAAGTATCGGCTATGGATTT
TATTTTTAAAGATGACCCTGCCGAACTTAAAACTCGTATTATCGATTGCCTTGAAACCGCACATACGCGCTTAAAGTTAT
TGTCAAAAGAACGTACCGTTGAAACGATAGAGCTTAAGCGCGGTAGTAATTCTGTATATGTGCAATATGATGAAGTGATG
TTTTTTGAATCATCAACAAATTCACATCGATTGATTGCACATTTAGATAATCGTCAAATTGAGTTTTATGGTAATCTAAA
ACAAATTAGTCAAATCGATGATCGTTTCTTTAGATGCCATAATAGTTTTGTTGTCAATCGACACAATATCTCTTCAATCA
ATTCAAAAGAACGTGTTGTATATTTTAAAAATGGTGAACATTGTTATGCATCAGTACGCAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

86.555

100

0.866

Multiple sequence alignment