Detailed information    

insolico Bioinformatically predicted

Overview

Name   comQ   Type   Regulator
Locus tag   GO004_RS18810 Genome accession   NZ_CP046591
Coordinates   3630519..3631382 (+) Length   287 a.a.
NCBI ID   WP_043858576.1    Uniprot ID   A8D459
Organism   Bacillus subtilis strain R31     
Function   modification of ComX; production of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 3625519..3636382
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GO004_RS18780 (GO004_18775) pncA 3625984..3626535 (+) 552 WP_014477836.1 isochorismatase family cysteine hydrolase -
  GO004_RS18785 (GO004_18780) pncB 3626551..3628023 (+) 1473 WP_003228788.1 nicotinate phosphoribosyltransferase -
  GO004_RS18790 (GO004_18785) pdeH 3628160..3629389 (+) 1230 WP_024572553.1 cyclic di-GMP phosphodiesterase -
  GO004_RS18795 (GO004_18790) - 3629365..3629733 (-) 369 WP_014477834.1 hypothetical protein -
  GO004_RS18800 (GO004_18795) - 3629847..3629972 (-) 126 WP_003228793.1 hypothetical protein -
  GO004_RS18805 (GO004_18800) degQ 3630194..3630334 (+) 141 WP_003220708.1 degradation enzyme regulation protein DegQ Regulator
  GO004_RS18810 (GO004_18805) comQ 3630519..3631382 (+) 864 WP_043858576.1 polyprenyl synthetase family protein Regulator
  GO004_RS18815 (GO004_18810) comX 3631384..3631605 (+) 222 WP_014480704.1 competence pheromone ComX -
  GO004_RS18820 (GO004_18815) comP 3631621..3633933 (+) 2313 WP_195727738.1 histidine kinase Regulator
  GO004_RS18825 (GO004_18820) comA 3634014..3634658 (+) 645 WP_003220716.1 two-component system response regulator ComA Regulator
  GO004_RS18830 (GO004_18825) yuxO 3634677..3635057 (+) 381 WP_015714624.1 hotdog fold thioesterase -
  GO004_RS18835 (GO004_18830) mnhG 3635096..3635470 (-) 375 WP_003244302.1 monovalent cation/H(+) antiporter subunit G -
  GO004_RS18840 (GO004_18835) mrpF 3635454..3635738 (-) 285 WP_003228814.1 Na(+)/H(+) antiporter subunit F1 -
  GO004_RS18845 (GO004_18840) mrpE 3635738..3636214 (-) 477 WP_029318490.1 Na+/H+ antiporter subunit E -

Sequence

Protein


Download         Length: 287 a.a.        Molecular weight: 32760.38 Da        Isoelectric Point: 4.9534

>NTDB_id=353654 GO004_RS18810 WP_043858576.1 3630519..3631382(+) (comQ) [Bacillus subtilis strain R31]
MKEIVDENILNEDLKVKLISFIEEKKQFSFAELAYYHYIAFDGKNDKAIELLASGIELLILSADIFDDIEDKDNLQASWM
KLDPSIATNAATALYTLSLQVIGSVSNHPKLLSLTLQYSLQSLQGQHVDLNLTASSESEYIEMIKLKSGSLVTLPSILGV
YLATGECNETVEEYSRYLGVVEQIANDHYGLYYPNNNDFKTRHTLAFNYLKNKFNQSSIDLLNFYAQENHMINNLEDLKG
KLRESGVIQYLNVIKNLAVENFKESFKKLRLDEQRKNKLLIQLLRGI

Nucleotide


Download         Length: 864 bp        

>NTDB_id=353654 GO004_RS18810 WP_043858576.1 3630519..3631382(+) (comQ) [Bacillus subtilis strain R31]
ATGAAGGAGATTGTGGATGAAAATATTTTAAATGAGGACTTAAAAGTGAAGCTCATTTCTTTTATCGAAGAAAAAAAACA
ATTTTCATTTGCAGAACTGGCTTATTACCATTACATAGCATTTGATGGAAAAAACGACAAAGCAATTGAGTTACTGGCGT
CAGGTATAGAACTTTTAATTTTATCTGCGGACATTTTTGACGATATTGAGGATAAGGACAATCTTCAGGCTTCTTGGATG
AAATTAGATCCTTCTATAGCAACTAACGCAGCTACCGCACTTTATACATTAAGTCTGCAGGTAATAGGCTCAGTCTCAAA
TCATCCAAAACTTTTAAGCCTTACTTTGCAATATTCACTCCAATCTTTACAAGGACAACATGTAGATTTGAATTTAACAG
CCTCATCAGAATCAGAGTATATTGAAATGATTAAACTTAAGTCGGGTTCTCTGGTAACATTGCCCAGTATTCTTGGTGTA
TATCTGGCAACTGGAGAATGTAATGAAACAGTTGAGGAGTATTCACGTTATTTAGGTGTAGTCGAGCAAATTGCAAATGA
TCACTATGGACTTTATTACCCTAACAATAATGACTTCAAAACTAGACATACGCTTGCCTTCAATTATCTTAAAAATAAAT
TTAACCAATCATCAATTGACTTATTAAATTTTTATGCGCAAGAAAATCATATGATAAATAATTTGGAAGATTTGAAGGGA
AAGTTAAGAGAATCAGGTGTAATACAATATTTGAATGTTATAAAAAATTTAGCAGTGGAAAATTTTAAGGAATCATTCAA
AAAACTGAGATTAGATGAACAAAGAAAAAATAAATTACTTATTCAATTATTAAGGGGGATTTAA

Domains

Predicted by InterProScan.

Polyprenyl synthetase (polyprenyl_synt)

(46-194)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A8D459

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comQ Bacillus subtilis subsp. subtilis str. 168

44.286

97.561

0.432