Detailed information NTG0353035

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: E4T54_RS04550
• Genome accession: NZ_CP038271
• Coordinates: 1040238..1043000 (+)
• Length: 920 a.a.
• NCBI ID: WP_172607336.1
• Uniprot ID: -
• Organism: Legionella geestiana strain 1308
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1035238..1048000

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E4T54_RS11995	-	1038192..1038347 (-)	156	WP_155832455.1	hypothetical protein	-
E4T54_RS04540 (E4T54_04540)	-	1038441..1038662 (-)	222	WP_028385924.1	hypothetical protein	-
E4T54_RS04545 (E4T54_04545)	gltX	1038735..1040144 (-)	1410	WP_028385925.1	glutamate--tRNA ligase	-
E4T54_RS04550 (E4T54_04550)	letS	1040238..1043000 (+)	2763	WP_172607336.1	two-component system sensor histidine kinase LetS	Regulator
E4T54_RS04555 (E4T54_04555)	-	1043011..1044243 (+)	1233	WP_028385926.1	6-phosphofructokinase	-
E4T54_RS04560 (E4T54_04560)	comP	1044253..1044696 (-)	444	WP_028385927.1	pilin	Machinery gene
E4T54_RS04565 (E4T54_04565)	-	1044814..1045137 (+)	324	WP_028385928.1	BolA family protein	-
E4T54_RS04570 (E4T54_04570)	-	1045214..1046617 (+)	1404	WP_028385929.1	APC family permease	-

Sequence

Protein

• Length: 920 a.a.
• Molecular weight: 102648.35 Da
• Isoelectric Point: 6.6785

>NTDB_id=353035 E4T54_RS04550 WP_172607336.1 1040238..1043000(+) (letS) [Legionella geestiana strain 1308]
MGIKYQLRVTTLIPVLLVALLFAVFYNGQYGHDLKQHMSRLGEAYIRQLLPAAQFAMLQKDARTLQGLINASSINPEIKT
IAFYNREGELLAYRGGKHSLVKPFSPPPFTGDYIESRHIDTNTIHFVAPVTLPQYNLYAPRPAVSHRVPLAWQPDDVLGW
LSIDIDTQSTLIKRYQMYMVTTFITLLGLLIGLSVHFFFARRIYLPITRLRRSMSQILRNEFETPVRTTSHGDLGTIERG
CAYLQRQYLDAVEDLNQHIETATADLQQSLELLEEKNVELLLEKKKAEEKSRQKSEFIANMSHEIRTPMNGVIGFTNVLL
EGKLDPLQMDYVKTIKSSAHDLLTIINDILDYSKMDAGKLHLDCIPLDIRACIDEVLTLSAPNAHRKGLDLIPITDVSVP
HMVLGDPLRIKQIIRNLVGNAVKFTDRGFVLVRTHIQAETQRDYTLCLSVTDTGIGIAPEDQTRLFNAFNQADTTIIRRF
GGTGLGLVICKKLTEEMQGKISLESTPHKGSTFSVTLRLEKLTAYEVEKNQSRRFAHLSALCFDENPLHLEALCNGLGYW
GVQCTPTGNLKELEEMMRSSQSFDIAFVHVNQGCERQIAPILKIRNLPAVAVAKQFIPDHDTLGAAAFLFKPISIQKLMD
TLEMLQNTATPSLEPEQARLRTRLQSVCPDVLLAEDNAVNRLLMNSLLAGHARVVAVSDGEEAVALCDTKRFHAILLDLQ
MPRMGGLEAASRIRHASLLNRDTPIAVISANSTDLHAEQLQKAGVSLCLQKPVDEKELFEYLLDALHQAQNAVIDWPVCL
QKASNNEALAREFMARFVEDLVKERPEFVRFFATNQVKALENAAHRLHGACCFCGVPKLMEQVVLLETSARGASDCASLE
DIFRAFLESLDAVAAAWANGDFAASAASSLPSKAIESSHP

Nucleotide

• Length: 2763 bp

>NTDB_id=353035 E4T54_RS04550 WP_172607336.1 1040238..1043000(+) (letS) [Legionella geestiana strain 1308]
ATGGGAATCAAATACCAGCTGCGTGTTACCACCCTCATTCCAGTACTGCTGGTTGCCCTTCTTTTTGCGGTATTTTATAA
CGGCCAGTACGGGCACGATCTTAAACAGCACATGTCACGCCTTGGGGAGGCTTACATTCGTCAGCTTCTGCCAGCCGCCC
AGTTTGCCATGCTGCAAAAAGACGCCCGCACGCTTCAGGGACTTATCAACGCATCTTCCATCAACCCTGAAATCAAAACC
ATCGCATTTTATAACCGTGAGGGCGAACTGCTCGCCTATCGCGGCGGCAAGCATTCGCTGGTCAAACCCTTCTCACCGCC
CCCTTTTACCGGCGACTATATCGAAAGCCGTCATATCGACACCAACACCATCCACTTTGTGGCTCCCGTGACGCTGCCAC
AATATAACCTCTACGCCCCACGGCCTGCCGTATCGCACAGAGTTCCCCTCGCCTGGCAGCCTGATGACGTGCTTGGCTGG
CTCTCTATCGATATCGACACCCAGTCAACCCTCATCAAGCGCTATCAGATGTATATGGTGACCACGTTCATCACGCTGCT
TGGCCTGCTCATTGGACTCAGCGTGCATTTTTTCTTCGCACGCCGCATTTATCTGCCAATTACCCGCCTGCGACGCAGCA
TGAGCCAGATTCTGCGCAACGAGTTTGAAACCCCGGTGCGCACGACCAGTCACGGGGACCTTGGTACCATCGAGCGCGGC
TGTGCGTATCTGCAGCGACAATATCTGGATGCCGTTGAAGATTTAAACCAGCACATCGAAACCGCCACCGCCGACCTGCA
GCAAAGCCTTGAGCTTTTGGAAGAAAAAAACGTTGAACTGCTGCTCGAAAAGAAAAAAGCGGAGGAAAAAAGCCGCCAGA
AATCGGAATTCATTGCCAATATGAGCCATGAAATCCGTACCCCCATGAACGGCGTTATCGGCTTTACCAATGTGCTGCTC
GAGGGCAAACTCGACCCCCTGCAGATGGATTATGTTAAAACCATTAAATCTTCGGCGCATGATTTACTGACCATCATCAA
CGACATCCTTGATTATTCCAAAATGGATGCGGGCAAACTGCACCTTGACTGCATTCCCCTCGATATCCGCGCCTGTATCG
ATGAGGTCCTGACGCTTTCTGCTCCCAACGCGCACCGCAAGGGACTTGACCTTATCCCGATTACCGATGTTTCGGTGCCG
CACATGGTGCTTGGCGACCCGCTGCGCATCAAGCAGATTATCCGAAACCTCGTTGGCAACGCGGTCAAATTTACCGACAG
AGGCTTCGTGCTGGTGCGTACCCATATTCAGGCGGAAACCCAGAGAGATTACACCCTCTGCCTCTCAGTGACTGACACCG
GCATTGGCATTGCACCAGAAGATCAGACCCGGCTCTTCAATGCGTTTAACCAGGCCGACACCACTATTATCCGCCGTTTT
GGCGGTACCGGTCTTGGACTTGTTATCTGCAAAAAACTGACGGAAGAGATGCAGGGTAAAATCAGTCTCGAGAGTACGCC
ACACAAAGGCTCTACCTTTTCAGTCACCCTGCGGCTGGAAAAACTCACGGCCTATGAAGTCGAAAAAAATCAAAGCCGCC
GATTCGCGCACCTTTCCGCACTCTGTTTTGATGAAAATCCACTGCATCTTGAAGCACTTTGCAATGGCCTTGGATACTGG
GGCGTCCAGTGTACTCCGACCGGTAACCTCAAAGAACTGGAAGAGATGATGCGCTCGAGTCAAAGCTTTGATATCGCATT
TGTGCACGTCAACCAGGGCTGCGAGCGCCAGATAGCTCCCATTCTTAAAATTCGCAACCTCCCGGCTGTCGCCGTTGCCA
AACAATTCATACCTGATCATGATACTCTGGGTGCGGCCGCTTTCCTGTTTAAGCCCATCAGCATTCAAAAACTCATGGAT
ACCCTGGAGATGCTGCAGAATACGGCAACCCCGTCTCTCGAGCCCGAGCAGGCGCGTCTGCGTACACGTTTACAATCAGT
TTGTCCCGATGTGCTGCTTGCAGAAGACAATGCCGTTAACCGGCTCTTGATGAATTCACTGCTGGCCGGACACGCACGGG
TGGTCGCGGTATCGGATGGGGAAGAAGCCGTGGCACTGTGCGATACCAAGCGTTTCCATGCGATTCTTCTTGATTTACAG
ATGCCGCGCATGGGGGGACTCGAGGCCGCTTCGCGCATCCGTCATGCCTCGCTGTTAAACCGCGATACTCCCATCGCGGT
TATCAGCGCGAACAGTACTGACCTGCATGCCGAACAACTGCAAAAAGCCGGGGTGAGCCTGTGCCTGCAAAAGCCTGTGG
ATGAGAAAGAGCTGTTTGAGTACCTGCTTGATGCCCTGCACCAGGCGCAAAATGCCGTCATTGACTGGCCGGTCTGTCTG
CAAAAAGCATCTAATAATGAGGCACTTGCCCGCGAATTTATGGCGCGCTTTGTAGAGGATTTGGTAAAAGAGCGTCCTGA
ATTCGTCCGTTTTTTTGCCACCAATCAAGTCAAAGCGCTGGAAAATGCCGCGCACAGGCTCCATGGAGCCTGCTGCTTTT
GCGGGGTGCCAAAGCTGATGGAGCAGGTGGTGCTCCTTGAAACCAGCGCACGCGGCGCCAGTGACTGCGCATCGCTTGAG
GATATTTTCCGTGCATTCCTCGAAAGCCTTGATGCAGTAGCTGCTGCGTGGGCAAACGGCGATTTTGCTGCCAGCGCAGC
CTCATCCCTGCCGTCAAAAGCCATAGAATCGTCTCACCCATGA

Domains

Predicted by InterproScan.

• Hpt domain (Hpt) (813-892)

• His Kinase A (phospho-acceptor) domain (HisKA) (294-358)

• Single cache domain 4 (sCache_4) (32-176)

• Response regulator receiver domain (Response_reg) (671-781)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (405-520)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	62.528	98.043	0.613