Detailed information NTG0353026

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: SaO408_RS13795
• Genome accession: NZ_CP038270
• Coordinates: 2677413..2678300 (-)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain O408 isolate B115
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 2672413..2683300

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SaO408_RS13760	-	2672415..2672507 (+)	93	WP_010956583.1	hypothetical protein	-
SaO408_RS13765 (SaO408_2552)	-	2672615..2673112 (-)	498	WP_120672894.1	glutathione peroxidase	-
SaO408_RS13770	-	2673122..2673382 (-)	261	WP_078064828.1	hypothetical protein	-
SaO408_RS13780	-	2673764..2673877 (-)	114	WP_072491147.1	hypothetical protein	-
SaO408_RS13785 (SaO408_2553)	-	2674553..2676553 (-)	2001	WP_000776723.1	ABC transporter permease	-
SaO408_RS13790 (SaO408_2554)	-	2676550..2677305 (-)	756	WP_000923770.1	ABC transporter ATP-binding protein	-
SaO408_RS13795 (SaO408_2555)	braS	2677413..2678300 (-)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
SaO408_RS13800 (SaO408_2556)	braR	2678311..2678976 (-)	666	WP_000697877.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
SaO408_RS13805 (SaO408_2557)	-	2679002..2679202 (-)	201	WP_000604725.1	hypothetical protein	-
SaO408_RS13810 (SaO408_2558)	-	2679400..2680824 (+)	1425	WP_043039787.1	alkaline phosphatase	-
SaO408_RS14495 (SaO408_2559)	-	2680884..2680985 (-)	102	WP_000731972.1	SE2200 family small protein	-
SaO408_RS13820 (SaO408_2560)	-	2681107..2681562 (-)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
SaO408_RS13825 (SaO408_2561)	-	2681807..2682568 (-)	762	WP_000323448.1	alpha/beta hydrolase family protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=353026 SaO408_RS13795 WP_000143420.1 2677413..2678300(-) (braS) [Staphylococcus aureus strain O408 isolate B115]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=353026 SaO408_RS13795 WP_000143420.1 2677413..2678300(-) (braS) [Staphylococcus aureus strain O408 isolate B115]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTTATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAACAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGGCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACTCACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993