Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   SaO408_RS10620 Genome accession   NZ_CP038270
Coordinates   2069913..2070629 (+) Length   238 a.a.
NCBI ID   WP_000688492.1    Uniprot ID   A0A7U7IEW1
Organism   Staphylococcus aureus strain O408 isolate B115     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2064913..2075629
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SaO408_RS10590 (SaO408_1964) - 2065128..2065754 (+) 627 WP_000522378.1 nitroreductase family protein -
  SaO408_RS10595 (SaO408_1965) - 2066115..2066900 (+) 786 WP_000867945.1 carbon-nitrogen family hydrolase -
  SaO408_RS14475 (SaO408_1966) - 2067500..2067634 (-) 135 WP_001549197.1 delta-lysin family phenol-soluble modulin -
  SaO408_RS10605 (SaO408_1967) - 2067870..2068433 (+) 564 WP_001105702.1 accessory gene regulator B family protein -
  SaO408_RS10610 (SaO408_1968) - 2068437..2068577 (+) 141 WP_000735197.1 cyclic lactone autoinducer peptide AgrD -
  SaO408_RS10615 (SaO408_1969) - 2068602..2069894 (+) 1293 WP_000387816.1 quorum-sensing sensor histidine kinase AgrC -
  SaO408_RS10620 (SaO408_1970) agrA 2069913..2070629 (+) 717 WP_000688492.1 LytTR family DNA-binding domain-containing protein Regulator
  SaO408_RS10625 - 2070701..2070808 (+) 108 WP_001803734.1 hypothetical protein -
  SaO408_RS10630 (SaO408_1971) - 2070992..2071954 (-) 963 WP_001253304.1 carbohydrate kinase -
  SaO408_RS10635 (SaO408_1972) - 2071951..2073435 (-) 1485 WP_000141424.1 sucrose-6-phosphate hydrolase -
  SaO408_RS10640 (SaO408_1973) - 2073584..2074534 (-) 951 WP_000790321.1 LacI family DNA-binding transcriptional regulator -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27905.90 Da        Isoelectric Point: 6.0927

>NTDB_id=353022 SaO408_RS10620 WP_000688492.1 2069913..2070629(+) (agrA) [Staphylococcus aureus strain O408 isolate B115]
MKIFICEDDPKQRENMVTIIKNYIMIEEKPMEIALATDNPYEVLEQAKNMNDIGCYFLDIQLSTDINGIKLGSEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPAELRTRIIDCLETAHTRLQLLSKDNSVETIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELSQLDDRFFRCHNSFVVNRHNIESIDSKERIVYFKNKEHCYASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=353022 SaO408_RS10620 WP_000688492.1 2069913..2070629(+) (agrA) [Staphylococcus aureus strain O408 isolate B115]
ATGAAAATTTTCATTTGCGAAGACGATCCAAAACAAAGAGAAAACATGGTTACCATTATTAAAAATTATATAATGATAGA
AGAAAAGCCTATGGAAATTGCCCTCGCAACTGATAATCCTTATGAGGTGCTTGAGCAAGCTAAAAATATGAATGACATAG
GCTGTTACTTTTTAGATATTCAACTTTCAACTGATATTAATGGTATCAAATTAGGCAGTGAAATTCGTAAGCATGATCCA
GTTGGTAACATTATATTTGTTACGAGTCACAGTGAACTTACCTATTTAACGTTTGTCTACAAAGTTGCAGCGATGGACTT
TATTTTTAAAGATGATCCAGCTGAATTAAGAACTCGAATTATAGACTGTTTAGAAACTGCACATACACGCTTACAATTGT
TGTCTAAAGATAATAGCGTTGAAACGATTGAATTAAAACGTGGCAGTAATTCAGTGTATGTTCAATATGATGATATTATG
TTTTTTGAATCGTCAACAAAATCTCACAGACTCATTGCCCATTTAGATAACCGTCAAATTGAATTTTATGGTAATTTAAA
AGAACTGAGTCAATTAGATGATCGTTTCTTTAGATGTCATAATAGCTTTGTCGTCAATCGCCATAATATTGAATCTATAG
ATTCGAAAGAGCGAATTGTCTATTTTAAAAATAAAGAACACTGCTATGCATCGGTGAGAAACGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-120)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7IEW1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

100

100

1

Multiple sequence alignment