Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   GOM46_RS07920 Genome accession   NZ_CP046525
Coordinates   1613643..1615592 (-) Length   649 a.a.
NCBI ID   WP_235083536.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1608643..1620592
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS07890 (GOM46_07835) - 1609538..1610482 (+) 945 WP_006149653.1 magnesium transporter CorA family protein -
  GOM46_RS07895 (GOM46_07840) - 1610495..1611169 (+) 675 WP_235083532.1 DUF1129 domain-containing protein -
  GOM46_RS07900 (GOM46_07845) - 1611370..1611633 (+) 264 WP_006149211.1 SemiSWEET family transporter -
  GOM46_RS07905 (GOM46_07850) - 1611691..1612359 (-) 669 WP_235083533.1 CPBP family intramembrane glutamic endopeptidase -
  GOM46_RS07910 (GOM46_07855) - 1612356..1612919 (-) 564 WP_235083534.1 DNA-3-methyladenine glycosylase I -
  GOM46_RS07915 (GOM46_07860) ruvA 1612929..1613522 (-) 594 WP_235083535.1 Holliday junction branch migration protein RuvA Machinery gene
  GOM46_RS07920 (GOM46_07865) hexB 1613643..1615592 (-) 1950 WP_235083536.1 DNA mismatch repair endonuclease MutL Machinery gene
  GOM46_RS07925 (GOM46_07870) tyrS 1615776..1617032 (+) 1257 WP_006149597.1 tyrosine--tRNA ligase -
  GOM46_RS07930 (GOM46_07875) - 1617086..1617934 (+) 849 WP_235083537.1 putative RNA methyltransferase -
  GOM46_RS07935 (GOM46_07880) glgP 1618005..1620263 (-) 2259 WP_235083538.1 glycogen/starch/alpha-glucan family phosphorylase -

Sequence

Protein


Download         Length: 649 a.a.        Molecular weight: 73567.09 Da        Isoelectric Point: 5.7354

>NTDB_id=352973 GOM46_RS07920 WP_235083536.1 1613643..1615592(-) (hexB) [Streptococcus infantis strain SO]
MSHIIELPEVLANQIAAGEVIERPASVVKELVENAIDAGSRQIIVEIEEAGLKKIQITDNGHGIAHDEVELALRRHATSK
IKNQADLFRIRTLGFRGEALPSIASVSVLTLLTAVDGASHGTKLVARGGEVEEIIPATSPVGTKVCVEDLFFNTPARLKY
MKSQQAELSHIIDIVNRLGLAHPEISFSLLSDGKEMTRTAGTGQLRQAIAGIYGLASAKKMVEIENSDLDFEISGFVSLP
ELTRANRNYISLFINGRYIKNFLLNRAILDGYGSKLMVGRFPLAVIHIQIDPYLADVNVHPTKQEVRISKERELMALVSE
AIAKSLKEQTLIPDALENLAKSTIRNREKVEQTTLPLRENTLYYEKNEPTRPKQAEVADHQVNLTEEKQDLNLFAKETLD
QITKPAKLHFAERKSVSYDQLDHPELDLASLDKAYDKLEREESSSFPELEFFGQMHGTYLFAQGRDGLYIIDQHAAQERV
KYEEYRESIGNVDQSQQQLLVPYIFEFPADDALRLKERMPLLEEVGVFLAEYGENQFILREHPIWMAEEEIESGIYEMCD
MLLLTKEVSIKKYRAELAIMMSCKRSIKANHRIDDHSARQLLYQLSKCDNPYNCPHGRPVLVHFTKSDMEKMFRRIQENH
TSLRELGKY

Nucleotide


Download         Length: 1950 bp        

>NTDB_id=352973 GOM46_RS07920 WP_235083536.1 1613643..1615592(-) (hexB) [Streptococcus infantis strain SO]
ATGTCTCATATTATTGAATTGCCAGAAGTCTTGGCCAACCAGATTGCAGCAGGAGAAGTGATCGAGCGTCCTGCCAGCGT
AGTTAAAGAGTTGGTCGAAAATGCTATCGACGCTGGCTCAAGACAGATTATCGTTGAGATCGAAGAAGCTGGTCTTAAGA
AAATCCAAATTACCGATAATGGGCACGGGATTGCCCACGATGAAGTCGAGTTAGCTCTCCGCCGTCATGCGACCAGTAAG
ATTAAGAATCAAGCGGATCTCTTTCGGATTCGGACTCTTGGTTTTCGTGGAGAGGCTCTGCCTTCTATCGCATCTGTTAG
TGTACTGACTCTTTTGACAGCAGTGGATGGCGCAAGTCATGGAACCAAGCTAGTGGCTCGTGGGGGAGAAGTTGAAGAAA
TCATCCCTGCGACCAGTCCTGTTGGGACCAAGGTTTGTGTGGAGGATCTCTTTTTCAACACACCAGCCCGTCTCAAGTAT
ATGAAGAGCCAACAGGCAGAGTTGTCTCATATCATCGATATTGTCAATCGTCTAGGCTTGGCCCATCCTGAGATTTCCTT
TAGCCTGCTTAGCGATGGCAAGGAAATGACACGGACAGCTGGTACGGGTCAACTGCGCCAAGCCATTGCTGGAATCTATG
GTCTAGCCAGTGCTAAAAAGATGGTTGAGATTGAGAATTCTGACCTAGATTTTGAAATTTCAGGTTTTGTCTCATTGCCG
GAATTGACACGTGCTAATCGCAACTATATCAGTCTCTTTATCAATGGCCGTTATATCAAAAACTTCTTGCTCAATCGTGC
CATTTTAGATGGTTACGGTAGCAAACTCATGGTAGGGCGTTTTCCGCTGGCCGTTATTCACATCCAGATCGATCCTTATC
TAGCAGATGTCAATGTTCATCCAACCAAGCAAGAAGTGCGGATTTCCAAGGAAAGAGAGCTGATGGCGCTAGTTTCAGAA
GCTATCGCAAAGAGTCTCAAGGAACAGACCTTGATTCCTGATGCCTTGGAAAATTTAGCCAAATCTACCATTCGCAATCG
TGAAAAAGTAGAGCAAACCACTTTACCATTGAGAGAAAATACGCTCTACTATGAAAAAAATGAACCGACAAGACCAAAAC
AAGCTGAGGTGGCAGACCATCAGGTGAACCTGACTGAAGAGAAACAGGATTTGAACCTCTTTGCTAAGGAAACCTTAGAC
CAGATAACCAAACCAGCCAAACTGCATTTTGCAGAGAGAAAGTCTGTCAGTTACGACCAACTAGACCATCCAGAGTTAGA
TCTAGCTAGTTTGGATAAGGCTTATGATAAGCTGGAGCGAGAAGAGTCTTCGAGCTTCCCAGAGTTAGAATTTTTCGGGC
AGATGCACGGTACCTACCTCTTTGCCCAAGGTCGAGATGGGCTTTACATCATAGATCAGCATGCGGCCCAGGAGCGGGTT
AAGTACGAGGAGTACCGCGAAAGCATTGGCAATGTTGACCAGAGTCAACAACAACTCCTAGTGCCTTACATCTTTGAATT
CCCTGCAGATGATGCCCTTCGTCTCAAGGAAAGAATGCCTCTCTTAGAGGAAGTTGGCGTCTTTCTAGCAGAGTACGGGG
AGAATCAATTTATCCTACGGGAACATCCAATTTGGATGGCAGAGGAGGAAATCGAGTCTGGTATCTATGAGATGTGTGAT
ATGCTCCTTTTGACAAAGGAAGTTTCTATCAAGAAATACCGAGCAGAGCTGGCCATTATGATGTCCTGCAAGCGGTCAAT
CAAGGCTAACCACCGTATCGATGACCACTCAGCTAGACAGCTCCTCTATCAGCTCTCTAAATGCGACAACCCATACAACT
GTCCACACGGACGCCCTGTTTTGGTGCATTTTACCAAGTCAGATATGGAAAAGATGTTCCGTCGCATTCAGGAAAATCAC
ACGAGTCTACGAGAACTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(450-592)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-107)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

94.915

100

0.949