Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpE   Type   Regulator
Locus tag   GOM46_RS02060 Genome accession   NZ_CP046525
Coordinates   399428..401530 (+) Length   700 a.a.
NCBI ID   WP_235083836.1    Uniprot ID   -
Organism   Streptococcus infantis strain SO     
Function   repress competence development (at the early growth phase) (predicted from homology)   
Competence regulation

Genomic Context

Location: 394428..406530
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  GOM46_RS02045 (GOM46_02030) - 394529..395374 (+) 846 WP_235083834.1 undecaprenyl-diphosphate phosphatase -
  GOM46_RS02050 (GOM46_02035) dinB 395410..396471 (-) 1062 WP_235083835.1 DNA polymerase IV -
  GOM46_RS02055 (GOM46_02040) pflB 396711..399026 (+) 2316 WP_006150108.1 formate C-acetyltransferase -
  GOM46_RS02060 (GOM46_02045) clpE 399428..401530 (+) 2103 WP_235083836.1 AAA family ATPase Regulator
  GOM46_RS02065 (GOM46_02050) - 401586..402068 (-) 483 WP_235083837.1 S-ribosylhomocysteine lyase -
  GOM46_RS02070 (GOM46_02055) amiA 402274..404250 (+) 1977 WP_235083839.1 peptide ABC transporter substrate-binding protein Regulator
  GOM46_RS02075 (GOM46_02060) pbp1a 404328..406472 (-) 2145 WP_235083840.1 penicillin-binding protein PBP1A -

Sequence

Protein


Download         Length: 700 a.a.        Molecular weight: 77405.19 Da        Isoelectric Point: 4.7608

>NTDB_id=352907 GOM46_RS02060 WP_235083836.1 399428..401530(+) (clpE) [Streptococcus infantis strain SO]
MNNNFNNFNNMDDLFNQLMGGMRGYSSENRRYLINGREVTPEEFAIYRQTGQLPSEGSDQAQYVQGKGMKQDGILAKLGR
NLTAEAREGKLDPVIGRNKEIQETSEILSRRTKNNPVLVGDAGVGKTAVVEGLAQAIVNGDVPAAIKNKEIISIDISGLE
AGTQYRGSFEENIQNLVNEVKEAGNIILFFDEIHQILGAGSTGDGQGSKGLADILKPALSRGELTVIGATTQDEYRNTIL
KNAALARRFNEVKVNAPSAEDTFKILQGIRDLYQQHHNVILPDEVLKAAVDYSVQYIPQRSLPDKAIDLVDVTAAHLAAQ
HPVTDVHAVEHEIEEEKAKQEAAAAKEDYEAALNAKVRIEELEKQIANHTEDHKVTATVNDVAESVERMTGIPVSQMGAT
DIERLKDMGHRLQTKVIGQDKAVEAVAKAIRRNRAGFDEGNRPIGSFLFVGPTGVGKTELAKQLALDMFGTKDAIIRLDM
SEYSDRTAVSKLIGTTAGYVGYDDNSNTLTERVRRNPYSIVLLDEIEKADPQVITLLLQVLDDGRLTDGQGNTVNFKNTV
IIATSNAGFGYEANLTEDADKPELMDRLKPYFRPEFLNRFNAVIEFSHLSKEDLSKIVDLMLIDVNKTLSKKEIDLAVSD
AAKEYMTEEGYDEVMGVRPLRRVVEQQIRDKVTDFHLDNLDAKHLEADMEDGILVIREKA

Nucleotide


Download         Length: 2103 bp        

>NTDB_id=352907 GOM46_RS02060 WP_235083836.1 399428..401530(+) (clpE) [Streptococcus infantis strain SO]
ATGAATAACAACTTTAATAACTTTAACAACATGGATGATTTGTTTAACCAATTGATGGGTGGTATGCGTGGATACAGTTC
TGAAAATCGTCGTTATTTGATTAACGGTCGTGAAGTAACACCTGAAGAATTCGCGATTTACCGTCAAACAGGTCAACTTC
CTAGCGAAGGAAGTGATCAAGCTCAGTACGTTCAAGGGAAAGGTATGAAACAAGACGGTATTCTTGCAAAACTTGGACGT
AATTTAACTGCTGAAGCTCGTGAAGGGAAGCTAGATCCGGTTATTGGACGTAACAAGGAAATTCAAGAAACTTCTGAAAT
TCTTTCTCGTCGTACAAAAAACAATCCAGTTCTTGTCGGTGATGCTGGTGTTGGTAAAACTGCTGTAGTAGAAGGCCTTG
CACAAGCTATTGTGAATGGTGATGTTCCAGCAGCAATCAAGAACAAAGAAATCATTTCAATTGATATTTCTGGACTTGAA
GCTGGTACTCAATACCGTGGTAGCTTTGAAGAAAATATTCAAAACTTGGTAAACGAAGTCAAGGAAGCTGGGAATATTAT
CCTCTTCTTCGACGAAATTCACCAAATCCTTGGCGCAGGTAGCACAGGGGATGGTCAAGGATCTAAAGGACTTGCTGATA
TCTTGAAACCAGCTCTTTCACGTGGGGAATTGACCGTGATTGGTGCAACAACTCAAGATGAATATCGTAATACAATCTTG
AAAAACGCTGCTCTTGCTCGTCGTTTCAACGAAGTAAAAGTTAATGCACCATCTGCTGAAGATACTTTCAAAATTCTCCA
AGGGATCCGTGATCTTTATCAACAACACCACAATGTTATCTTGCCAGATGAAGTATTGAAAGCGGCTGTTGATTACTCTG
TTCAATATATTCCACAACGTAGCTTGCCTGATAAGGCTATCGACCTTGTTGATGTGACAGCTGCTCACTTGGCAGCACAA
CACCCAGTGACAGATGTACATGCTGTGGAACATGAAATTGAAGAAGAAAAAGCTAAACAAGAAGCTGCAGCTGCTAAAGA
AGATTATGAAGCAGCTTTAAATGCAAAAGTTCGTATCGAAGAACTTGAAAAGCAAATTGCTAACCATACAGAAGATCACA
AGGTTACAGCGACTGTAAATGACGTAGCTGAGTCTGTAGAACGTATGACAGGTATTCCTGTTTCACAAATGGGTGCAACT
GATATTGAACGTTTGAAAGATATGGGCCACCGTTTGCAAACTAAGGTTATCGGTCAAGACAAGGCTGTTGAAGCCGTTGC
CAAAGCGATTCGTCGGAACCGTGCAGGTTTTGATGAAGGAAATCGCCCAATCGGTAGCTTCCTCTTTGTAGGACCTACTG
GTGTTGGTAAAACAGAATTGGCTAAACAATTGGCACTTGATATGTTCGGTACTAAAGATGCCATCATTCGTTTGGACATG
TCAGAATACAGTGACCGCACAGCCGTTTCTAAATTGATTGGTACAACAGCTGGTTATGTTGGTTATGATGACAATAGCAA
TACTTTGACAGAACGTGTTCGCCGTAACCCTTACTCAATCGTCCTTCTCGACGAAATTGAAAAGGCTGACCCTCAAGTGA
TTACTCTTCTTCTTCAAGTATTGGATGATGGTCGTTTGACAGATGGTCAAGGTAACACTGTAAACTTCAAGAATACTGTG
ATTATCGCAACTTCAAACGCAGGATTTGGCTATGAAGCGAACTTGACAGAAGATGCAGACAAACCAGAATTGATGGATCG
TTTGAAACCTTACTTCCGTCCAGAATTCCTCAATCGTTTCAACGCTGTGATTGAATTCTCACACTTGAGCAAAGAAGATC
TTTCTAAGATTGTTGATTTGATGTTGATTGATGTTAATAAGACTCTTTCTAAGAAAGAAATCGACTTGGCAGTGAGCGAT
GCAGCCAAAGAATACATGACTGAAGAAGGTTATGATGAAGTCATGGGTGTTCGTCCTCTCCGTCGTGTGGTTGAACAACA
GATTCGTGATAAAGTGACAGATTTCCATTTGGATAATCTTGATGCTAAACACCTAGAAGCTGATATGGAAGATGGTATTT
TGGTCATTCGTGAAAAAGCCTAA

Domains

Predicted by InterProScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(442-602)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(609-679)

ATPase family associated with various cellular activities (AAA) (AAA)

(117-249)

AAA lid domain (AAA_lid_9)

(258-352)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpE Streptococcus mutans UA159

47.421

99.714

0.473
  clpC Lactococcus lactis subsp. cremoris KW2

47.143

100

0.471
  clpE Streptococcus pneumoniae Rx1

48.973

90.429

0.443
  clpE Streptococcus pneumoniae D39

48.973

90.429

0.443
  clpE Streptococcus pneumoniae R6

48.973

90.429

0.443
  clpE Streptococcus pneumoniae TIGR4

49.042

89.429

0.439
  clpC Bacillus subtilis subsp. subtilis str. 168

45.763

92.714

0.424
  clpC Streptococcus pneumoniae Rx1

41.203

95

0.391
  clpC Streptococcus pneumoniae D39

41.203

95

0.391
  clpC Streptococcus pneumoniae TIGR4

41.203

95

0.391
  clpC Streptococcus thermophilus LMD-9

42.95

88.143

0.379
  clpC Streptococcus thermophilus LMG 18311

42.811

88.429

0.379
  clpC Lactococcus lactis subsp. lactis strain DGCC12653

42.788

88.143

0.377
  clpC Streptococcus mutans UA159

41.935

88.571

0.371