Detailed information NTG0352762

Bioinformatically predicted

Overview

• Name: letS
• Type: Regulator
• Locus tag: E3983_RS03625
• Genome accession: NZ_CP038254
• Coordinates: 813506..816241 (-)
• Length: 911 a.a.
• NCBI ID: WP_135059906.1
• Uniprot ID: A0AAX1EEI9
• Organism: Legionella israelensis strain HL-0427-4011
• Function: regulate competence development (predicted from homology) Competence regulation

Genomic Context

Location: 808506..821241

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
E3983_RS03595 (E3983_03595)	-	809429..809860 (-)	432	WP_135059901.1	secondary thiamine-phosphate synthase enzyme YjbQ	-
E3983_RS03600 (E3983_03600)	-	809853..810173 (-)	321	WP_342447553.1	BolA family protein	-
E3983_RS03605 (E3983_03605)	-	810324..810851 (+)	528	WP_135059902.1	transposase	-
E3983_RS03610 (E3983_03610)	-	810954..811406 (+)	453	WP_135059903.1	hypothetical protein	-
E3983_RS03615 (E3983_03615)	pilA2	811647..812066 (+)	420	WP_209025857.1	pilin	Machinery gene
E3983_RS03620 (E3983_03620)	-	812226..813476 (-)	1251	WP_135059905.1	6-phosphofructokinase	-
E3983_RS03625 (E3983_03625)	letS	813506..816241 (-)	2736	WP_135059906.1	two-component system sensor histidine kinase LetS	Regulator
E3983_RS03630 (E3983_03630)	-	816315..816545 (+)	231	WP_058502248.1	hypothetical protein	-
E3983_RS03635 (E3983_03635)	gltX	816517..817929 (+)	1413	WP_135059907.1	glutamate--tRNA ligase	-
E3983_RS03640 (E3983_03640)	-	817990..818478 (-)	489	WP_135059908.1	YchJ family metal-binding protein	-
E3983_RS03645 (E3983_03645)	-	818602..819312 (+)	711	WP_135059909.1	glutathione S-transferase C-terminal domain-containing protein	-

Sequence

Protein

• Length: 911 a.a.
• Molecular weight: 103433.65 Da
• Isoelectric Point: 7.7284

>NTDB_id=352762 E3983_RS03625 WP_135059906.1 813506..816241(-) (letS) [Legionella israelensis strain HL-0427-4011]
MKSLGIKYQLRITTLIPVLLVALLFALFYNGQFSKDLKQHMSRLGEAYIRQLMPAAQYALQQDNHRTLQGLINASTINQE
VKAVAFYDANGRLLAYRGGKHSLKKPFTPPAFTGDFIESKQLNSTTINFFAPITIPKYNLYSTDILRPSTQNFILQPDDI
LGWLSINIDTQSMLIKRYQMMIVTIFITLFGLLIGLATHYFLSKRIYMPISRLRRSMKQILRNEFETEIRVSSAGELGVI
EEGCAHLQKQYLDTIRDLNHHIEVATADLQQSLELLEEKNIELSMEKKKSEEKNRQKSEFIANMSHEIRTPMNGVIGFTN
VLLESKLDPLQLDYVKTIKTSAQDLLQIINDILDYSKMDAGKLHLDCIPLDIRACIDEVLVLSAPNAHKKGIDLIPITSL
EVPRTVLGDPLRIKQIISNLVNNAIKFTDKGYVLIRTEVEQEMANDYLLRISVSDTGIGISKEDQSKLFTAFNQADTSIT
RRYGGSGLGLVICKKLAEEMKGRISLSSDLHKGSTFSVHIRVEKLSSYEVEKNQNYRFAHLKVLCFDENRLQLESITNGL
GHWGIQCTTVNAFDKLAKALEHNKNCDFAFINVKQGYEAQIAELLKAHPNKTYILVSKWPIADVKSFGAQAFLYQPISIQ
KLHDIIESLMHQPSVPPSLVPQEVENLREQLRFSHPDILIAEDNPVNRMLLNSLLGENANMESVSDGEQAVVVCNEKRFQ
VILLDLQMPKLNGLEAAKKIRHESLLNRHTPILLLSASSTDINRDKLKNAGIDHCLHKPVEEKQLISHLLRLMDKAQHAA
IDWSLCVQKLSGNQKLAEDFLARFVEELKKDRLELIQLMRDKNIRGLASAAHKLHGACSFCGVPMLQKKVREFEIMTQQV
KNSEDLRSLFAELVQRIDAVIDEYENYYSES

Nucleotide

• Length: 2736 bp

>NTDB_id=352762 E3983_RS03625 WP_135059906.1 813506..816241(-) (letS) [Legionella israelensis strain HL-0427-4011]
TTGAAAAGCCTTGGTATTAAATACCAGCTCAGGATTACAACACTTATTCCTGTGCTTCTCGTCGCTTTATTGTTTGCCTT
ATTTTATAACGGTCAATTCAGCAAAGATTTAAAACAACACATGTCGCGTCTCGGCGAAGCTTACATTCGCCAATTAATGC
CAGCTGCTCAGTATGCCTTACAGCAGGATAACCATCGGACTCTGCAAGGGCTCATTAACGCTTCTACCATCAATCAGGAA
GTGAAAGCCGTTGCTTTCTACGATGCCAATGGACGTCTGCTCGCTTATCGCGGAGGAAAACATTCTCTGAAAAAACCCTT
TACTCCTCCAGCCTTTACCGGTGATTTTATAGAAAGCAAGCAACTGAATTCCACCACCATTAATTTTTTCGCCCCCATCA
CTATCCCAAAATATAACTTATATTCCACGGATATACTGAGACCTTCAACCCAGAATTTTATTTTACAGCCAGATGATATT
TTGGGATGGCTGTCTATCAATATTGATACCCAATCCATGTTGATCAAGCGCTATCAAATGATGATTGTTACGATTTTTAT
TACGCTGTTTGGATTACTGATTGGCTTGGCCACGCATTATTTTTTGTCAAAACGCATTTATATGCCTATCAGCCGATTAC
GCAGGAGCATGAAACAGATTTTAAGGAATGAATTTGAGACAGAAATTCGCGTTTCAAGCGCAGGGGAGCTGGGTGTTATT
GAGGAGGGCTGTGCCCATTTGCAGAAACAATATCTCGACACCATACGTGATCTGAATCATCATATTGAAGTGGCCACGGC
TGACCTGCAACAAAGCCTTGAATTGCTGGAAGAAAAAAACATCGAATTATCGATGGAGAAGAAAAAATCAGAAGAAAAAA
ACCGGCAAAAATCAGAATTCATTGCCAACATGAGCCATGAAATCCGTACCCCTATGAATGGGGTGATTGGTTTTACTAAC
GTATTGCTGGAAAGTAAACTGGATCCCTTACAGCTCGATTATGTTAAAACGATCAAAACTTCTGCTCAGGATCTATTACA
AATCATCAACGACATTCTTGATTATTCAAAAATGGATGCCGGTAAACTCCATCTCGACTGTATACCTCTTGACATACGGG
CCTGCATTGATGAGGTTCTTGTTCTCTCTGCTCCCAATGCTCACAAAAAAGGCATTGACTTGATTCCAATTACCTCTCTC
GAGGTTCCAAGAACGGTTCTCGGTGATCCATTACGCATTAAACAAATCATATCCAATCTGGTGAACAATGCCATAAAATT
TACCGATAAAGGATACGTTCTTATCCGAACCGAGGTTGAGCAGGAGATGGCAAATGATTACCTGCTTCGCATCTCTGTAT
CCGATACCGGCATAGGGATTTCAAAAGAGGATCAGAGTAAATTATTTACAGCATTCAATCAGGCCGATACCAGCATTACC
CGTCGCTACGGCGGCTCCGGCCTTGGCCTTGTCATTTGCAAGAAACTGGCTGAAGAAATGAAAGGACGCATCAGCCTGAG
TAGCGATTTACATAAGGGTTCAACCTTCTCCGTTCATATTCGTGTGGAGAAACTCTCATCCTATGAAGTTGAAAAAAATC
AGAATTATCGTTTTGCTCATCTTAAAGTGTTATGCTTTGACGAAAACAGACTGCAACTGGAATCCATTACCAATGGCTTA
GGCCACTGGGGCATACAGTGCACTACTGTCAATGCCTTTGACAAATTAGCCAAAGCCTTAGAGCATAATAAAAACTGCGA
TTTCGCCTTTATTAACGTCAAACAAGGATATGAAGCGCAGATTGCCGAGCTTCTCAAAGCTCACCCGAATAAAACTTACA
TTCTTGTTTCAAAATGGCCAATTGCGGATGTCAAATCCTTCGGCGCACAAGCTTTTTTATACCAACCCATTAGCATCCAG
AAACTTCATGACATTATTGAATCCTTAATGCATCAACCATCAGTCCCCCCTTCACTTGTGCCTCAGGAAGTTGAAAATTT
GAGAGAACAACTGAGATTTTCTCATCCTGATATCCTGATAGCGGAAGATAATCCGGTCAACCGTATGTTGTTAAACTCCC
TGCTCGGTGAAAATGCAAATATGGAATCAGTAAGTGATGGTGAGCAAGCAGTCGTAGTCTGTAATGAAAAACGTTTCCAG
GTCATACTCCTCGATCTGCAAATGCCAAAGCTCAACGGACTCGAAGCTGCCAAAAAAATTCGACATGAATCTTTACTCAA
TCGTCATACGCCTATTCTTTTATTAAGCGCCAGCAGTACCGATATTAATCGCGATAAATTAAAAAACGCCGGTATTGATC
ATTGCCTGCATAAGCCTGTTGAGGAAAAACAACTCATCAGTCATTTACTTCGTTTGATGGACAAGGCTCAACACGCAGCC
ATCGACTGGTCCTTATGTGTGCAGAAACTGTCCGGTAACCAGAAGCTCGCTGAAGATTTTCTCGCCCGTTTTGTAGAAGA
ATTAAAAAAAGACAGGCTTGAATTGATTCAGTTGATGCGCGACAAAAACATTCGTGGTCTTGCCAGTGCCGCACACAAAT
TACATGGGGCCTGCAGTTTCTGTGGCGTTCCTATGTTGCAGAAAAAAGTAAGAGAATTTGAAATCATGACCCAGCAGGTC
AAAAATTCAGAAGATTTACGCTCACTTTTCGCTGAATTAGTCCAGCGTATTGACGCCGTTATTGATGAATATGAAAATTA
TTACAGCGAATCTTAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (297-361)

• Single cache domain 4 (sCache_4) (35-179)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (408-523)

• Hpt domain (Hpt) (820-900)

• Response regulator receiver domain (Response_reg) (678-788)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
letS	Legionella pneumophila strain ERS1305867	71.099	99.89	0.71