Detailed information NTG0352715

Bioinformatically predicted

Overview

• Name: amiE
• Type: Regulator
• Locus tag: ES298_RS08865
• Genome accession: NZ_CP038253
• Coordinates: 1747773..1748840 (-)
• Length: 355 a.a.
• NCBI ID: WP_000159554.1
• Uniprot ID: A0A062WMA1
• Organism: Streptococcus pneumoniae strain TVO_1901929
• Function: internalize XIP (predicted from homology) Competence regulation

Genomic Context

Location: 1742773..1753840

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ES298_RS08840 (ES298_09340)	treR	1742960..1743670 (+)	711	WP_000760673.1	trehalose operon repressor	Regulator
ES298_RS08845 (ES298_09345)	-	1743703..1744506 (-)	804	WP_000157672.1	ABC transporter ATP-binding protein	-
ES298_RS08850 (ES298_09350)	-	1744519..1745396 (-)	878	Protein_1773	ABC transporter permease	-
ES298_RS08855 (ES298_09355)	-	1745408..1746217 (-)	810	Protein_1774	ABC transporter substrate-binding protein	-
ES298_RS08860 (ES298_09360)	amiF	1746836..1747762 (-)	927	WP_001291294.1	ATP-binding cassette domain-containing protein	Regulator
ES298_RS08865 (ES298_09365)	amiE	1747773..1748840 (-)	1068	WP_000159554.1	ABC transporter ATP-binding protein	Regulator
ES298_RS08870 (ES298_09370)	amiD	1748849..1749775 (-)	927	WP_000103700.1	oligopeptide ABC transporter permease OppC	Regulator
ES298_RS08875 (ES298_09375)	amiC	1749775..1751271 (-)	1497	WP_000759905.1	ABC transporter permease	Regulator
ES298_RS08880 (ES298_09380)	amiA3	1751338..1753317 (-)	1980	WP_000742236.1	peptide ABC transporter substrate-binding protein	Regulator

Sequence

Protein

• Length: 355 a.a.
• Molecular weight: 39490.09 Da
• Isoelectric Point: 4.8727

>NTDB_id=352715 ES298_RS08865 WP_000159554.1 1747773..1748840(-) (amiE) [Streptococcus pneumoniae strain TVO_1901929]
MTKEKNVILTARDIVVEFDVRDKVLTAIRGVSLELVEGEVLALVGESGSGKSVLTKTFTGMLEENGRIAQGSIDYRGQDL
TALSSHKDWEQIRGAKIATIFQDPMTSLDPIKTIGSQITEVIVKHQGKTAKEAKELAIDYMNKVGIPDADRRFNEYPFQY
SGGMRQRIVIAIALACRPDVLICDEPTTALDVTIQAQIIDLLKSLQNEYHFTTIFITHDLGVVASIADKVAVMYAGEIVE
YGTVEEVFYDPRHPYTWSLLSSLPQLADDKGDLYSIPGTPPSLYTDLKGDAFALRSDYAMQIDFEQKAPQFSVSETHWAK
TWLLHEDAPKVEKPAVIANLHDKIREKMGFAHLAD

Nucleotide

• Length: 1068 bp

>NTDB_id=352715 ES298_RS08865 WP_000159554.1 1747773..1748840(-) (amiE) [Streptococcus pneumoniae strain TVO_1901929]
ATGACAAAAGAAAAAAATGTAATTTTGACTGCTCGCGATATTGTCGTGGAATTTGACGTTCGTGACAAAGTATTGACAGC
CATTCGCGGCGTTTCCCTTGAACTAGTTGAAGGAGAAGTATTAGCCTTGGTAGGTGAGTCAGGATCAGGTAAATCTGTTT
TGACAAAGACCTTCACAGGTATGCTCGAAGAAAATGGTCGTATTGCCCAAGGTAGTATTGACTACCGTGGTCAGGACTTG
ACAGCTTTATCTTCTCACAAGGATTGGGAACAAATTCGTGGTGCTAAGATTGCGACTATCTTCCAGGACCCAATGACTAG
TTTGGACCCCATTAAAACAATTGGTAGTCAGATTACAGAAGTTATTGTAAAACACCAAGGAAAAACAGCTAAAGAAGCGA
AAGAATTGGCCATTGACTACATGAATAAGGTTGGCATTCCAGACGCAGATAGACGTTTTAATGAATACCCATTCCAATAT
TCTGGAGGAATGCGTCAACGTATCGTTATTGCGATTGCCCTTGCCTGCCGACCTGATGTCTTGATCTGTGATGAGCCAAC
AACTGCCTTGGATGTAACTATTCAAGCTCAGATTATTGATTTGCTAAAATCTTTACAAAACGAGTATCATTTCACAACAA
TCTTTATTACCCACGACCTTGGTGTGGTGGCAAGTATTGCGGATAAGGTAGCGGTTATGTATGCAGGAGAAATCGTTGAG
TATGGAACGGTTGAGGAAGTCTTCTATGACCCTCGCCATCCATATACATGGAGTCTCTTGTCTAGCTTGCCTCAGCTTGC
TGATGATAAAGGGGATCTTTACTCAATCCCAGGAACACCTCCGTCACTTTATACTGACCTGAAAGGGGATGCTTTTGCCT
TGCGTTCTGACTACGCAATGCAGATTGACTTCGAACAAAAAGCTCCTCAATTCTCAGTATCAGAGACACATTGGGCTAAA
ACTTGGCTTCTTCATGAGGATGCTCCAAAAGTAGAAAAACCAGCTGTGATTGCAAATCTCCATGATAAGATCCGTGAAAA
AATGGGATTTGCCCATCTGGCTGACTAG

Domains

Predicted by InterproScan.

• Oligopeptide/dipeptide transporter, C-terminal region (oligo_HPY) (239-301)

• ABC transporter (ABC_tran) (29-187)

3D structure

• AlphaFold DB: A0A062WMA1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
amiE	Streptococcus salivarius strain HSISS4	88.169	100	0.882
amiE	Streptococcus thermophilus LMG 18311	86.479	100	0.865
amiE	Streptococcus thermophilus LMD-9	86.479	100	0.865
oppD	Streptococcus mutans UA159	54.545	99.155	0.541